All hotels in De Soto, Illinois
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in De Soto, Illinois
We have found 233 De Soto Hotels
- Drury Inn & Suites Marion
- Baymont by Wyndham Marion
- Quality Inn Carbondale University area
- Super 8 by Wyndham Carbondale
- Motel 6 Marion, IL
- Holiday Inn Carbondale-Conference Center, an IHG Hotel
- Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
- Super 8 by Wyndham Du Quoin
- Fairfield Inn and Suites by Marriott Marion
- Hampton Inn Marion
- Comfort Inn & Suites Carbondale University Area
Let Expedia take you to the best Hotels in De Soto. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.