Photo by Serendipity Trip

Southeastern Indiana 4 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana 4 Star Hotels

Our top choices for Southeastern Indiana 4-star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3,967 reviews)
"Great stay"
United States
Carlos
The price is P7,899
P9,294 total
includes taxes & fees
Jan 28 - Jan 29
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,758 reviews)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is P9,897
P11,645 total
includes taxes & fees
Jan 19 - Jan 20
Omni Louisville Hotel

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,148 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is P7,246
P8,526 total
includes taxes & fees
Jan 18 - Jan 19
Embassy Suites Louisville Downtown

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,171 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,026 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is P6,880
P8,095 total
includes taxes & fees
Jan 12 - Jan 13
Hotel Genevieve part of JdV by Hyatt

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent place. "
United States
Anatole
The price is P7,483
P9,101 total
includes taxes & fees
Feb 1 - Feb 2
21c Museum Hotel Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,002 reviews)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
The price is P8,760
P10,307 total
includes taxes & fees
Jan 19 - Jan 20
Hyatt Regency Louisville

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,000 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is P8,577
P10,091 total
includes taxes & fees
Jan 16 - Jan 17
The Grady

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is P10,651
P12,532 total
includes taxes & fees
Feb 1 - Feb 2
Louisville Marriott Downtown

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (432 reviews)
"Clean, well appointed, convenient to restaurants and downtown Louisville."
United States
Chris
The price is P10,378
P12,211 total
includes taxes & fees
Feb 8 - Feb 9
Hotel Distil, Autograph Collection

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (62 reviews)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is P9,964
P11,724 total
includes taxes & fees
Jan 21 - Jan 22
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,001 reviews)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is P8,440
P9,931 total
includes taxes & fees
Jan 18 - Jan 19
Seelbach Hilton Louisville Downtown

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is P6,984
P11,198 total
includes taxes & fees
Feb 9 - Feb 10
Stellar Suites

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (651 reviews)
"This is our second visit this year. Lovely and comfortable rooms. Breakfast was wonderful "
United States
douglas f
The price is P5,263
P5,948 total
includes taxes & fees
Jan 13 - Jan 14
The Pepin Mansion Historic B&B

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very Good, (26 reviews)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is P4,089
P11,624 total
includes taxes & fees
Jan 27 - Jan 28
CozySuites at Nulu

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (46 reviews)
"room very good i love hotel ❤️"
United States
Kartar
The price is P8,819
P9,966 total
includes taxes & fees
Jan 12 - Jan 13
stayAPT Suites Louisville North-Clarksville

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1 review)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is P9,766
P14,296 total
includes taxes & fees
Jan 14 - Jan 15
The Reserve on Main

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
TWO Stunning Nulu CozySuites

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944 reviews)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.
Photo by Serendipity Trip
Open Photo by Serendipity Trip

Top Southeastern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favorite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travelers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your vacation in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from P5,948

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.

Explore a world of travel with Expedia