Zona 21 Trips (flight + hotel)

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Where to stay in Zona 21

Find the best Zona 21 areas and neighborhoods for the activities you enjoy most. Learn more about Zona 21
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Zona 10

4 out of top 10 points of interest in this area

Zona 10 is known for its ample dining options, and you can make a stop by Oakland Mall and Plaza Fontabella Shopping Center while in the area.

Find hotels in Zona 10

Top hotels in Zona 21

Barceló Guatemala City
Barceló Guatemala City
4.5 out of 5
7 Avenida 15-45, Zona 9, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is P3,954 per night from Aug 3 to Aug 4
P3,954
P4,824 total
Aug 3 - Aug 4
includes taxes & fees
9/10 Wonderful! (2,892 reviews)
"Staff is friendly. They let us check in early and also let us check out late. Unheard of in most hotel chains. Everything is close. I will come back!"

Reviewed on Jul 3, 2025

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,006 reviews)
"Possibly the most incredible hotel we’ve ever stayed at. Ever."

Reviewed on Jul 4, 2025

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Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City
Wyndham Garden Guatemala City
4 out of 5
1a Avenida 12-46 Zona 10, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is P5,417 per night from Jul 13 to Jul 14
P5,417
P6,609 total
Jul 13 - Jul 14
includes taxes & fees
9/10 Wonderful! (1,449 reviews)
"This hotel is super nice, the staff are very helpful and professional. The breakfast is top notch. Comfortable bed, very spacious room."

Reviewed on Jul 3, 2025

Wyndham Garden Guatemala City
See all 1,128 properties in Zona 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Zona 21 vacation package cost?
Live it up in Zona 21 from as low as . Choose from a great selection of hotels, flights and rental cars to suit every budget. Land even better deals when you add a couple of experiences or tours to your vacation package.
How do I get a cheap travel package to Zona 21?
Bundle your bookings with Expedia to save big bucks on your next big adventure. With more than 550 airlines and 1,000,000 hotels worldwide, your Zona 21 vacation package can be customized exactly to suit your budget. With all that extra money, why not include a few interesting experiences and tours? It's an easy way to unlock even more discounts. The vacation you've always dreamed of in Zona 21 is much closer than you thought!
Where should I stay in Zona 21?
With so much to discover in Zona 21, it'd be convenient for you to secure a room in a hotel close to its attractions. Mundo Petapa, Universidad del San Carlos de Guatemala and Embassy of El Salvador are some fascinating ones to add to your itinerary.
What are the top hotels in Zona 21?
House 23 and Beautiful House 20 Minutes From The Airport And 5 Minutes From Mundo Petapa Park are two of the most well-known hotels in Zona 21. Why not look up the amenities and facilities at each and then make a decision?
How far in advance should I book my Zona 21 vacation?
Browse Expedia to compare international flights ASAP. You can generally purchase a ticket up to 12 months in advance. If you can't see your preferred carrier, or you've left things to the last minute, don't worry. The lowest prices to Zona 21 sometimes emerge just weeks before the date of departure.
What does an Expedia Zona 21 travel package include?
Hotels, rental cars and flights, or any combination of them --- you decide! Whether you're headed to Zona 21 with the kids or adventuring solo, there's a bundle to suit your budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Zona 21 travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and unlock exciting discounts. Hotels aren't your only choice, though. Book with us and take your pick of beachside villas, rural cottages and just about everything in between!
Can I choose my airline with a Zona 21 Expedia vacation package?
Yes --- and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our vacation packages give you the freedom to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Zona 21 vacation package?
Your situation can change unexpectedly, so yes, you can. You may be able to cancel or amend your Zona 21 vacation package for free within 24 hours of booking. For bookings older than that, you can still cancel or make changes, but your hotel, car rental company or airline may charge additional fees. Want more information? Take a look at our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.

Popular places to visit

Paseo Cayala

During your trip to Guatemala City, you can browse for the perfect souvenirs at Paseo Cayala. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Paseo Cayala

Avenida La Reforma

You can learn about the history of Guatemala City with a stop at Avenida La Reforma. While in this family-friendly area, you can savor the top-notch restaurants.

Avenida La Reforma

Kaminaljuyu

Learn about the local history of Guatemala City with a stop at Kaminaljuyu. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

Kaminaljuyu

Things to do

Antigua Guatemala , Full-Day Shared Tour from Guatemala City

Antigua Guatemala , Full-Day Shared Tour from Guatemala City

P4,228
per adult
Antigua Guatemala , Full-Day Shared Tour from Guatemala City
From Lanquin: Semuc Champey Park and Kanba Cave Guided Tour

From Lanquin: Semuc Champey Park and Kanba Cave Guided Tour

P1,973
per adult
From Lanquin: Semuc Champey Park and Kanba Cave Guided Tour
See all activities in Guatemala City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.