Hotels with Spa, Uptown Cincinnati

A historic building with ornate architecture and a modern brick structure in the foreground.

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Our top choices for Uptown hotels with a spa

A modern hotel room with a bathroom, a sofa, and a bed.

A spiral staircase with a black metal railing and a white wall.

A hotel room with a wooden headboard, a bedside lamp, a laptop, and a framed picture on the wall.

A table with a glass of orange juice on a balcony overlooking a cityscape with buildings and a tower.

1. 21c Museum Hotel Cincinnati

Downtown Cincinnati

Luxuriate in rejuvenating spa treatments and facials at this boutique hotel with 3 dedicated wellness rooms.

P9,568

P11,729 total

includes taxes & fees

Nov 5 - Nov 6

A reception area with a reception desk, two armchairs, and a round table.

A modern bar area with a circular seating arrangement, a central bar counter, and a decorative light fixture.

A large brick building with a prominent entrance and a sign reading "The Lyole Hotel."

2. The Lytle Park Hotel, Autograph Collection

Downtown Cincinnati

P21,947

P26,183 total

includes taxes & fees

Oct 18 - Oct 19

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Choose what matters most at spa hotels in Uptown

Pool

Breakfast included

Hot tub

4 stars

5 stars

Top Uptown Hotel Reviews

Country Inn & Suites by Radisson, Cincinnati Airport, KY

10/10 Excellent

"They picked us up from airport very quickly. Breakfast was great!"

Hyatt Regency Cincinnati

10/10 Excellent

"V"

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