Hotels near St Mary's Medical Center

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for St Mary's Medical Center hotels

Fireplace
Castle Creek B&B

Castle Creek B&B

Castle Creek B&B
3.5 star property
0.8 km from St Mary's Medical Center
9.8 out of 10, Exceptional, (207)
"Very pleasant stay…Incredible breakfast"
United States
Michele
Castle Creek B&B
Terrace/patio
Hotel Maverick

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.2 km from St Mary's Medical Center
9.6 out of 10, Exceptional, (1002)
"Excellent place to stay in Grand Junction. "
United States
Steve
Hotel Maverick
Restaurant
Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 2.7 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (991)
"Very nice hotel and would choose it again"
United States
Billy
The price is P4,797
P5,500 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Tru by Hilton Grand Junction Downtown
View from property
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
3.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
9.0 out of 10, Wonderful, (1003)
"Very nice family hotel with good breakfast."
United States
Margarita
The price is P6,812
P7,850 total
includes taxes & fees
Dec 28 - Dec 29
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
Interior detail
The Hotel Melrose

The Hotel Melrose

The Hotel Melrose
2.0 star property
Historic Grand Junction, 2.7 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (133)
"Love this little hotel!"
United States
Gregory
The price is P11,891
P13,634 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Hotel Melrose
Restaurant
Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
8.8 out of 10, Excellent, (1002)
"Very clean, well managed, and a nice overall stay"
United States
Jeff
The price is P5,345
P6,128 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn Grand Junction Downtown/Historic Main Street
View from property
Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown
2.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
8.8 out of 10, Excellent, (688)
"Steve was super friendly and accommodating at both check in and check out. "
United States
Morey
The price is P6,666
P7,643 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Grand Junction Downtown
Lobby
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 2.8 km from St Mary's Medical Center
8.6 out of 10, Excellent, (1001)
"Great staff."
United States
Manford
The price is P3,277
P3,757 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn Grand Junction near University
Lobby
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction
4.0 star property
Horizon Drive District, 3 km from St Mary's Medical Center
8.2 out of 10, Very Good, (1003)
"Nice looking hotel."
United States
Richard
The price is P5,200
P5,963 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Doubletree Hotel Grand Junction
Lobby
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
2.0 star property
Horizon Drive District, 2.8 km from St Mary's Medical Center
7.4 out of 10, Good, (1002)
"Great staff"
United States
Theresa
The price is P3,095
P3,548 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Super 8 by Wyndham Grand Junction Colorado
Desk, blackout drapes, iron/ironing board, free WiFi
Ville 718

Ville 718

Ville 718
2.5 star property
Horizon Drive District, 2.7 km from St Mary's Medical Center
6.8 out of 10, (352)
"Very nice quiet place while traveling through town. "
United States
Shane
The price is P3,465
P3,973 total
includes taxes & fees
Dec 23 - Dec 24
Ville 718
Exterior
Days Inn by Wyndham Grand Junction

Days Inn by Wyndham Grand Junction

Days Inn by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 2.5 km from St Mary's Medical Center
5.4 out of 10, (1003)
"Very nice and clean "
United States
Ashley
The price is P2,986
P3,424 total
includes taxes & fees
Dec 29 - Dec 30
Days Inn by Wyndham Grand Junction
Exterior
Vintage Parlor 2 Bedroom Home

Vintage Parlor 2 Bedroom Home

Vintage Parlor 2 Bedroom Home
3.0 star property
Hawthorne Park, 1.6 km from St Mary's Medical Center
The price is P6,959
P23,978 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Vintage Parlor 2 Bedroom Home
Exterior
Home Away From Home 1 Bedroom Home

Home Away From Home 1 Bedroom Home

Home Away From Home 1 Bedroom Home
3.0 star property
Hawthorne Park, 1.7 km from St Mary's Medical Center
The price is P7,320
P24,503 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Home Away From Home 1 Bedroom Home
Living area
The Maverick Haus 3 Bedroom Townhouse

The Maverick Haus 3 Bedroom Townhouse

The Maverick Haus 3 Bedroom Townhouse
3.0 star property
Grandview, 1.5 km from St Mary's Medical Center
The Maverick Haus 3 Bedroom Townhouse
Exterior
My Home Is Your Home 2 Bedroom Home

My Home Is Your Home 2 Bedroom Home

My Home Is Your Home 2 Bedroom Home
3.0 star property
Hawthorne Park, 1.7 km from St Mary's Medical Center
The price is P7,536
P24,818 total
includes taxes & fees
Jan 11 - Jan 12, 2026
My Home Is Your Home 2 Bedroom Home
Dining
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 3.3 km from St Mary's Medical Center
8.8 out of 10, Excellent, (2737)
"Easy to check-in was a great quick stay"
United States
Stephanie
The price is P4,407
P5,053 total
includes taxes & fees
Dec 28 - Dec 29
La Quinta Inn & Suites by Wyndham Grand Junction
Exterior
Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG
3.0 star property
Horizon Drive District, 3.3 km from St Mary's Medical Center
8.6 out of 10, Excellent, (1004)
"Room was clean, front office staff was nice. "
United States
Patricia
The price is P5,226
P5,992 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn & Suites Grand Junction by IHG
Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi
Econo Lodge Grand Junction North

Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
2.0 star property
Horizon Drive District, 3.2 km from St Mary's Medical Center
8.4 out of 10, Very Good, (1000)
"Hotel was easy to find and worked quite well for a good night sleep after driving 13 hours. "
United States
Peter
The price is P3,504
P4,018 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Econo Lodge Grand Junction North
Indoor pool, open 7:00 AM to 10:00 PM, sun loungers
Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 3.8 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (881)
"Clean room, great breakfast, good service!"
United States
Sue
The price is P8,590
P9,849 total
includes taxes & fees
Dec 25 - Dec 26
Home2 Suites by Hilton Grand Junction Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St Mary's Medical Center Hotel Reviews

Clarion Inn Grand Junction

Clarion Inn Grand Junction

10/10 Excellent
"Verry nive stay"
justin 2-night trip
Posted 5 days ago
Clarion Inn Grand Junction

Hotels near other St Mary's Medical Center attractions

Western Colorado Center for the Arts

3.7/5 (46 reviews)
You can spend time exploring the galleries in Western Colorado Center for the Arts in Grand Junction. Check out the notable monuments and top-notch restaurants in this family-friendly area.
See properties

Elliott Tennis Center

Catch an event at Elliott Tennis Center during your trip to Grand Junction.
See properties

Frequently asked questions

What's the area like around St Mary's Medical Center?
St Mary's Medical Center is located in Grand Junction. This scenic area is known for its selection of wineries and hiking. If you're looking for a convenient place to stay, check out the 38 hotels and other accommodations you'll find within a mile.
What's the best place to stay near St Mary's Medical Center?
Hotel Maverick is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a fitness center. It's located just a short 0.7 mi (1.2 km) from St Mary's Medical Center. Another good choice is Castle Creek B&B, located just 0.5 mi (0.8 km) away.
How many hotels will I find near St Mary's Medical Center?
Expedia has 38 hotels and other accommodations within a mile from St Mary's Medical Center.
If I need to cancel the hotel reservation for my stay near St Mary's Medical Center, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review top deals close to St Mary's Medical Center.
What can I see and do near St Mary's Medical Center?
You'll want to browse the exhibits at Cross Orchards Historic Site and John McConnell Math and Science Center. You might spend a leisurely day outdoors at Western Colorado Botanical Gardens and Canyon View Park. Create some family memories at Bananas Fun Park, Grand Junction Motor Speedway, and Mesa County Fairgrounds while you're exploring the area around St Mary's Medical Center.