Top 10 Hotels Near St. Louis Science Center in St. Louis for 2026

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Our top choices for St. Louis Science Center hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A snack and treat display with various products, including chips and beverages, in a store setting.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 1 km from St. Louis Science Center

Jennifer

P8,658

P10,210 total

includes taxes & fees

Oct 4 - Oct 5

A lobby with a reception desk, seating area, and a bicycle in the background.

A spacious dining area with multiple tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

2. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Robert

P9,308

P10,884 total

includes taxes & fees

Oct 4 - Oct 5

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

A bar area with a marble counter, bar stools, and a variety of liquor bottles.

A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

A grand lobby with a central seating area, a staircase, and a decorative ceiling.

3. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 1.8 km from St. Louis Science Center

Tosha

P9,309

P12,820 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

A modern kitchen with a marble backsplash, built-in bar with stools, and shelves stocked with bottles.

A modern living room with a fireplace, comfortable seating, and a large TV.

4. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Molly

P9,771

P11,523 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with seating, planters, and a grill.

A modern hotel lobby with grey sofas, a coffee table, and a reception desk.

A spacious lobby with a modern design, featuring a seating area with sofas and armchairs, a reception desk, and a large window providing a view of the interior.

A building with a sign that reads "element by Westin" on a brick wall.

5. Element by Marriott St. Louis Midtown

Midtown, 2.7 km from St. Louis Science Center

Heather

P8,247

P9,643 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A group of people sitting on a couch in a well-lit room with a large plant and a floor lamp.

A modern cafe interior with a bar area, seating, and a menu board.

A hotel with a covered outdoor seating area, a parking lot, and a sign for a restaurant.

6. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Lydia

P8,434

P10,631 total

includes taxes & fees

Oct 4 - Oct 5

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A spacious dining area with marble tables and chairs, a kitchen in the background, and a modern ceiling design.

A reception area with a Christmas tree, a neon sign, and a Santa Claus figure.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

7. The West End

Central West End, 2.3 km from St. Louis Science Center

Deborah

P4,941

P7,028 total

includes taxes & fees

Sep 29 - Sep 30

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

A modern hotel with a prominent 'aloft' sign, a 'WXYZ' sign, and a 'Coming Soon' advertisement on the side.

A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

A modern bar area with seating, a bar counter, and a view of the cityscape.

8. Aloft by Marriott St Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Jacob

P7,116

P8,321 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

A compact kitchen with a stainless steel microwave, a sink, and a coffee maker.

A hotel coffee shop with a coffee machine, mugs, and a buffet area.

9. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

paullita jeanne

P9,714

P11,358 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

10. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Kevin

P9,621

P11,346 total

includes taxes & fees

Oct 25 - Oct 26

A spacious foyer with a grand staircase, a piano, and a large rug.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

11. White House at Grand Central

3 km from St. Louis Science Center

Triman

P5,037

P8,077 total

includes taxes & fees

Sep 29 - Sep 30

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A modern bedroom with a large bed, a sitting area with a sofa and chairs, a vanity with a mirror, and a ceiling fan.

A bedroom with a bed, a mirror, a dresser, and a chandelier.

12. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

P10,285

P12,940 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with two beds, a chair, a desk, and a large window.

A bathroom with a bathtub, toilet, and sink.

A lobby with seating areas, a reception desk, and a view through glass doors.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

13. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

Janice

P4,824

P5,933 total

includes taxes & fees

Oct 27 - Oct 28

A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.

A wooden surface with a metal rod and a power outlet with a red plug-in sign.

A Red Roof Plus hotel lobby with two leather chairs, a coffee station, and a sign indicating free Wi-Fi in all rooms.

A reception area with a counter, a clock, and a sign indicating free Wi-Fi availability.

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

Sean

P4,748

P5,552 total

includes taxes & fees

Oct 25 - Oct 26

A room with a green armchair, a round table, a lamp, and a mirror on the wall.

A bar area with a neon sign, a lamp, and various food and drink items.

A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

A two-story building with a dark entrance, large windows, and a brick facade.

15. Truitt Hotel

Lafayette Square, 4.9 km from St. Louis Science Center

Gabrielle

P10,496

P12,741 total

includes taxes & fees

Sep 29 - Sep 30

A rooftop terrace with wicker furniture, offering a city view.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

16. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.1 km from St. Louis Science Center

Salvatore

P8,434

P9,861 total

includes taxes & fees

Oct 3 - Oct 4

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A spa bath with a sign indicating a capacity of 8 persons.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

17. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

Janell

P8,496

P10,087 total

includes taxes & fees

Oct 4 - Oct 5

A log cabin with a stone chimney, wooden deck, and a staircase leading to the entrance.

A rustic wooden interior with a wooden bench displaying various animal carvings and a stone wall.

A rustic wooden bed with a quilt, a chair, and a view of the outdoors through a door.

A cozy bedroom with a stone fireplace, a bed with a patterned bedspread, and a television on a wooden stand.

18. The Lodge at Grant's Trail

10.1 km from St. Louis Science Center

Patricia

P11,808

P13,578 total

includes taxes & fees

Sep 29 - Sep 30

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

A modern living room with a sofa, coffee table, and bookshelves.

A modern bar area with a central fire feature, bar stools, and seating.

19. Live by Loews - St.Louis

Downtown St. Louis, 6.7 km from St. Louis Science Center

Frank

P9,934

P11,814 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel lobby with a glass facade, seating area, and a staircase.

A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

20. Four Seasons Hotel St Louis

7.5 km from St. Louis Science Center

Nicole

P23,428

P27,394 total

includes taxes & fees

Oct 4 - Oct 5

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Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,005 reviews	View
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,018 reviews	View
The Royal Sonesta Chase Park Plaza St. Louis	9.2 Wonderful 1,013 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 852 reviews	View
Element by Marriott St. Louis Midtown	8.8 Excellent 829 reviews	View

Top St. Louis Science Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"The parking garage wasn't as easy to find as I thought. I should have checked in first then gotten parking info. Clean, quiet and very safe. Walkable to restaurants. Staff was helpful and friendly."

Forest Park Hotel by MDR

8/10 Good

"I was only there to sleep and did not use any of the amenities. The noise from the highway and the trains was louder than at most hotels I have stayed at."

Hampton Inn & Suites St. Louis at Forest Park

10/10 Excellent

"The hotel is across the interstate from Forest Park, so it’s in a great location. The room was amazing and the front staff were so friendly and helpful."

The Cheshire

10/10 Excellent

"Very helpful staff, the breakfast fruit tray was amazing! Best cocktail I’ve had in forever at the Fox and Hound Pub, and great Starbucks too. Really enjoyed my stay!"

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Relaxing night unwinding on rooftop bar."

The West End

8/10 Good

"It was a comfortable quiet room. Didn't care for the shower. TV didn't allow access to many channels. Not sure why. But for the most part enjoyed our stay."

Element by Marriott St. Louis Midtown

8/10 Good

"We would appreciate for more light in the room. One of the lights at the headboard is not working. More rail on the wall in the bathroom to hang wet towels or when changing clothes inside. The hair blower has no warm or hot air so I had problem drying my hair and smooth out curls."

Drury Inn & Suites St. Louis Forest Park

10/10 Excellent

"Best hotel for the money that I have ever stayed at. And that is saying something. The breakfast is an outstanding selection of cooked food. The beds are super comfy for an old guy with a bad back. But what really stood out was the free dinner. They set out another selection of simple food, including very good pulled pork. We were not hungry enough to go out, so it was perfect. I will keep looking for Drury hotels in future traveling for sure!"

DoubleTree by Hilton St. Louis Forest Park

8/10 Good

"Safe surroundings and ambiance. Access to restaurant from Lobby convenient. The bathroom was not completely clean specifically the bathtub. The rest of the room was great"

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot.

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A theater stage with a variety of neon signs advertising different businesses.

The Muny Theater

8.6/10 (7 reviews)

You can enjoy a show at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

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Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game.

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Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 72 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good options within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.

How many hotels will I be able to find near St. Louis Science Center?

Expedia has 72 hotels and other accommodations within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum, and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box, and Sheldon Concert Hall are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater, and Powell Symphony Hall.

Hotels near St. Louis Science Center

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Treat yourself

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Our top choices for St. Louis Science Center hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Drury Inn & Suites St. Louis Forest Park

3. The Royal Sonesta Chase Park Plaza St. Louis

4. AC Hotel St. Louis Central West End

5. Element by Marriott St. Louis Midtown

6. Hotel Indigo St Louis - Central West End by IHG

7. The West End

8. Aloft by Marriott St Louis Central West End

9. Home2 Suites by Hilton St. Louis/Forest Park

10. DoubleTree by Hilton St. Louis Forest Park

11. White House at Grand Central

12. Central West End B&B

13. Forest Park Hotel by MDR

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

15. Truitt Hotel

16. Drury Plaza Hotel St. Louis at the Arch

17. Drury Plaza Hotel St. Louis Brentwood

18. The Lodge at Grant's Trail

19. Live by Loews - St.Louis

20. Four Seasons Hotel St Louis

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Forest Park Hotel by MDR

Hampton Inn & Suites St. Louis at Forest Park

The Cheshire

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

The West End

Element by Marriott St. Louis Midtown

Drury Inn & Suites St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions