A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Luxury Hotels in St. Charles, St. Louis

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Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,008 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is P9,093
P11,650 total
includes taxes & fees
Aug 3 - Aug 4
Ameristar Casino Resort and Spa

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (154 reviews)
The price is P7,957
P9,060 total
includes taxes & fees
Jul 23 - Jul 24
The Inn at Elijah McLeans

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.2 out of 10, Wonderful, (1,659 reviews)
The price is P5,915
P7,782 total
includes taxes & fees
Aug 2 - Aug 3
River City Casino & Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,009 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is P8,585
P10,210 total
includes taxes & fees
Jul 12 - Jul 13
Moonrise Hotel

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,012 reviews)
The price is P8,918
P10,583 total
includes taxes & fees
Jul 23 - Jul 24
Drury Plaza Hotel St. Louis Brentwood

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,004 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is P23,064
P26,969 total
includes taxes & fees
Jul 23 - Jul 24
Four Seasons Hotel St Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,204 reviews)
The price is P8,596
P10,138 total
includes taxes & fees
Jul 17 - Jul 18
Hyatt Regency St. Louis at The Arch

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,006 reviews)
The price is P10,183
P12,091 total
includes taxes & fees
Aug 2 - Aug 3
The Cheshire

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Opulent downtown retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
The price is P8,622
P10,082 total
includes taxes & fees
Aug 6 - Aug 7
The Westin St. Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,236 reviews)
The price is P9,798
P11,653 total
includes taxes & fees
Jul 17 - Jul 18
Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Frontier Park, and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.

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