Luxury Hotels in Southern Illinois, Illinois

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Luxury Hotels

Our top choices for Southern Illinois luxury hotels

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very Good, (805 reviews)
  • cleanliness
    Plush beds and serene pool define luxury at Mt. Vernon retreat where spa awaits after exploration.
The price is P7,671
P8,634 total
includes taxes & fees
Apr 18 - Apr 19
DoubleTree by Hilton Mt. Vernon

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (429 reviews)
  • cleanliness
    Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
The price is P7,796
P8,652 total
includes taxes & fees
Apr 15 - Apr 16
Walker's Bluff Casino Resort

DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
4.0 star property
Eastport
8.2 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Upscale St. Louis hotel offers steakhouse, indoor pool, and 24-hour fitness center.
The price is P8,223
P9,455 total
includes taxes & fees
May 14 - May 15
DoubleTree by Hilton Collinsville - St. Louis

Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
4.0 star property
Charleston
10.0 out of 10, Exceptional, (3 reviews)
The price is P7,008
P7,777 total
includes taxes & fees
Apr 20 - Apr 21
Charleston House Bed & Breakfast Inn

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is P9,550
P12,157 total
includes taxes & fees
Apr 28 - Apr 29
Ameristar Casino Resort and Spa

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is P28,195
P32,968 total
includes taxes & fees
Apr 15 - Apr 16
Four Seasons Hotel St Louis

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,019 reviews)
  • cleanliness
    Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
The price is P11,338
P15,140 total
includes taxes & fees
Apr 19 - Apr 20
The Royal Sonesta Chase Park Plaza St. Louis

Terre Haute Casino Resort

Terre Haute Casino Resort
4.0 star property
Terre Haute
9.2 out of 10, Wonderful, (851 reviews)
The price is P7,240
P8,326 total
includes taxes & fees
Apr 19 - Apr 20
Terre Haute Casino Resort

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,923 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is P8,314
P9,888 total
includes taxes & fees
Apr 20 - Apr 21
Moonrise Hotel

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,106 reviews)
The price is P10,281
P12,227 total
includes taxes & fees
May 8 - May 9
Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southern Illinois Hotel Reviews

Explore a world of travel with Expedia