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Business Hotels in Southern Illinois, Illinois

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Check availability on Southern Illinois Business Hotels

Tonight
Oct 21 - Oct 22
Tomorrow
Oct 22 - Oct 23
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Southern Illinois business-friendly hotels

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.
A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.
A hotel room with two beds, a large window, and a wall-mounted lamp.
An outdoor patio area with tables and chairs, large windows, and a stone wall.

1. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
Doug
P7,191
P8,107 total
includes taxes & fees
Oct 31 - Nov 1
Holiday Inn Express & Suites Mount Vernon by IHG
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

2. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
P7,001
P7,896 total
includes taxes & fees
Oct 26 - Oct 27
Drury Plaza Hotel Mt. Vernon
A hotel lobby with a reception desk, seating area, and a large screen TV.
A Comfort Suites hotel with a spacious parking lot and a modern brick facade.
A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.
A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

3. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
Mount Vernon
United States
Bruce and Robin
P7,490
P8,439 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Suites Mount Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.
A Fairfield Inn & Suites by Marriott hotel with a parking lot and a clear sky.
A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

4. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
United States
Susan
P6,326
P7,147 total
includes taxes & fees
Nov 6 - Nov 7
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.
A modern living area with a sectional sofa, a fireplace, and a flat-screen TV.
A treats section with a variety of snacks and beverages, including a refrigerated display and shelves stocked with items like Welch's and Bonde.
A hotel lobby with a large indoor pool, a reception desk, and a seating area.

5. Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
Effingham
United States
Claire
P7,989
P8,867 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Effingham
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.
A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.
A modern kitchen area with a counter, various appliances, and food display items.
An indoor swimming pool with lounge chairs and a clear view of the pool area.

6. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Steve
P6,810
P7,626 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Effingham
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.
An outdoor patio area with tables and chairs, large windows, and red umbrellas.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

7. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Kenneth
P7,487
P8,435 total
includes taxes & fees
Oct 30 - Oct 31
DoubleTree by Hilton Mt. Vernon
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.
An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.
A Country Inn & Suites building with a covered entrance and a parking lot.
A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.

8. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
Marion
United States
Lisa
P5,576
P6,691 total
includes taxes & fees
Nov 8 - Nov 9
Country Inn & Suites by Radisson, Marion, IL
A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.
A modern kitchen with a coffee station, fruit display, and a waffle advertisement.
A reception desk with a "Welcome to the Prairie State" sign, a receptionist, and a digital display.
A snack and treat section with shelves stocked with various snacks, a 'Welcome to our store' sign, and a 'Treats' sign.

9. Hampton Inn O'Fallon

Hampton Inn O'Fallon
O'Fallon
United States
Edmond
P7,185
P8,333 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn O'Fallon
A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.
A gym with treadmills, ellipticals, and weight machines.
A Best Western hotel with a parking lot and a covered entrance.
A spacious lobby with a sofa, chairs, a coffee table, and a dining area with tables and chairs.

10. Best Western Marion Hotel

Best Western Marion Hotel
Marion
United States
Cornell
P4,828
P5,793 total
includes taxes & fees
Oct 25 - Oct 26
Best Western Marion Hotel
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Top Southern Illinois Hotel Reviews

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

10/10 Excellent
"The front desk lady was helpful and nice. Room was clean and spacious. Breakfast runs low fast"
Emily 1-night trip
Posted less than an hour ago
Ramada by Wyndham Effingham
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"It was great like always"
Jason 1-night trip
Posted 19 hours ago
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

8/10 Good
"Had to leave 2 days early for medical issues and could not get any refund."
Charles 5-night trip
Posted 21 hours ago
Quality Inn & Suites Metropolis I-24
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"It was perfect for my son and I for SIUC homecoming"
Jeffrey 1-night trip
Posted 1 day ago
Drury Inn & Suites Marion
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"The only downfall was the indoor pool. I thought it would be heated. It wasn't. The kids still went in but we're shivering."
Michele 3-night trip
Posted 2 days ago
Quality Inn O'Fallon - St. Louis - Shiloh
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

10/10 Excellent
"Staff was amazing"
Ashtyn 1-night trip
Posted 2 days ago
Baymont by Wyndham Effingham
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Room was nice and clean, indoor pool little chilly. Breakfast choices were good. Parking good,"
brian 2-night trip
Posted 6 days ago
Holiday Inn Express Metropolis by IHG

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between P4,726 and P8,439 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travelers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travelers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 8.6.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at P4,726 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travelers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're traveling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travelers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favorite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're traveling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.

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