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Business Hotels in Southern Illinois, Illinois

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Check availability on Southern Illinois Business Hotels

Our top choices for Southern Illinois business-friendly hotels

Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,747 reviews)
"Great hotel with outstanding staff. Looking forward to staying there on our way home."
United States
Candy
The price is P7,162
P8,072 total
includes taxes & fees
Aug 3 - Aug 4
Drury Plaza Hotel Mt. Vernon
Exterior

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,000 reviews)
"Front desk ladies were great, as well as hotel"
United States
Cecil
The price is P6,564
P7,408 total
includes taxes & fees
Aug 9 - Aug 10
Holiday Inn Express & Suites Mount Vernon by IHG
Lobby

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,000 reviews)
"Great place for an overnight stay!! Clean, comfy beds and cold AC!"
United States
Lori
The price is P4,996
P5,545 total
includes taxes & fees
Jul 28 - Jul 29
SureStay Hotel by Best Western Whittington Rend Lake
Lobby

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,065 reviews)
"I love this place especially for traveling with children and pets. Easy access from the highway, close by restaurant options, pool for the kids, fenced pet walk area, great breakfast options, rooms are clean and well maintained with plenty of options for everyone to plug in devices."
United States
Denise
The price is P7,326
P8,253 total
includes taxes & fees
Aug 16 - Aug 17
Comfort Suites Mount Vernon
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,009 reviews)
"The staff at this location go above and beyond to ensure a wonderful stay"
United States
Tracie
The price is P6,174
P7,408 total
includes taxes & fees
Aug 9 - Aug 10
Drury Inn & Suites Marion
Desk, blackout drapes, iron/ironing board, WiFi (free)

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,005 reviews)
"Great price clean room friendly staff great breakfast"
United States
Matthew W,
The price is P4,275
P4,868 total
includes taxes & fees
Aug 9 - Aug 10
Super 8 by Wyndham Mt. Vernon IL
Indoor pool, sun loungers

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very Good, (870 reviews)
"Very nice hotel and service are great"
United States
Samuel
The price is P7,889
P8,879 total
includes taxes & fees
Aug 13 - Aug 14
DoubleTree by Hilton Mt. Vernon
Outdoor pool

Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
2.0 star property
Mount Vernon
6.6 out of 10, (1,001 reviews)
"Great stay and affordable"
United States
Norberto
The price is P4,457
P5,070 total
includes taxes & fees
Jul 30 - Jul 31
Days Inn by Wyndham Mount Vernon
Vending machine

Americas Best Value Inn Mount Vernon

Americas Best Value Inn Mount Vernon
2.5 star property
Mount Vernon
6.6 out of 10, (373 reviews)
"very friendly staff"
United States
Jim
The price is P4,442
P5,053 total
includes taxes & fees
Jul 25 - Jul 26
Americas Best Value Inn Mount Vernon
Terrace/patio

Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (790 reviews)
"The staff was very accommodating and friendly. The breakfast was great"
United States
Todd
The price is P5,936
P6,648 total
includes taxes & fees
Aug 9 - Aug 10
Holiday Inn Express & Suites Salem by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Lovely!!! Easy check-in. Right off the highway and you can see McAlister’s, Panera & Starbucks right next door. Room was super clean such a peaceful evening, great sleep"
Jessica 1-night trip
Posted 3 hours ago
Drury Plaza Hotel Mt. Vernon

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between P4,868 and P8,879 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travelers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travelers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 8.8.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at P4,868 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travelers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're traveling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travelers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favorite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're traveling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.

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