A mural of Red Wing with a steamship, houses, and a bridge.

Southeast Minnesota hotel rooms a the Independent

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 1 - Sep 2
Tomorrow
Sep 2 - Sep 3
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13
Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Minnesota Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"We stayed here prior to appt at Mayo just 5 minutes away. Great location north of the Clinic. Hotel offers shuttle service to Gonda Bldg and St. Mary’s., very helpful either construction, Easy walk to dwtn area. Fresh breakfast and friendly checkin."
Meg 1-night trip
Posted less than an hour ago
Hyatt House Rochester/Mayo Clinic Area
Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City

10/10 Excellent
"Jo jo and the house keeping manager elsa is amazing! I love this place"
Curtis 1-night trip
Posted 2 hours ago
Birch Hill Suite Rochester – Med City
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"Awesome hot tub and pool. Great views and area. Definitely would stay here again"
Carew 2-night trip
Posted 10 hours ago
Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"The location is so convenient- literally right across the street from Mayo. The breakfast was nice and the staff were all friendly."
Steve 4-night trip
Posted 12 hours ago
Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"The experience here is wonderful as are all the staff. A special shout out to Q, as he really helped me with navigating the traffic at Mayo. I really liked it because I could walk to everything. While the decor could use a bit of freshening up, the staff, location, and amenities made up for it. I would definitely stay here again."
Stacy 1-night trip
Posted 12 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good
"Property was older. Doors didn’t shut from the humidity from the pool area. Not enough space in the breakfast area. Had to stand every morning."
Elizabeth 2-night trip
Posted 13 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Aspen Select

Aspen Select

10/10 Excellent
"Very good experience. Accommodating to our needs."
matthew 3-night trip
Posted 2 days ago
Aspen Select
Treasure Island Resort & Casino

Treasure Island Resort & Casino

8/10 Good
"Very enjoyable experience"
Maryjo 1-night trip
Posted 2 days ago
Treasure Island Resort & Casino
St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America

8/10 Good
"Vert cool and unique stay! Loved the history and staff was friendly. My only complaint was worrying about a $50 fee you pay if you “check out at 11:01 “. Checkout is 11:00. I did not appreciate having a stress after enjoying a night out not to mention a very expensive hotel room already."
Tressa 1-night trip
Posted 3 days ago
St James Hotel, a Historic Hotel of America

Explore a world of travel with Expedia