A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

South San Diego Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for South San Diego vacation rentals

1. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,259 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
The price is P9,161
P10,621 total
includes taxes & fees
Nov 17 - Nov 18
Marriott Vacation Club®, San Diego

2. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (840 reviews)
"Amazing location, amenities, staff"
United States
Javier
The price is P10,448
P11,493 total
includes taxes & fees
Nov 30 - Dec 1
Coronado Beach Resort

3. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (239 reviews)
"Friendly staff!"
United States
Donavin
The price is P7,381
P10,481 total
includes taxes & fees
Dec 2 - Dec 3
City24 Hotel Little Italy Mission Hills

4. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (400 reviews)
"Great stay nice staff"
United States
Olivia
The price is P6,220
P7,199 total
includes taxes & fees
Nov 9 - Nov 10
Little Italy Inn - Limited Service Apart Hotel

5. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (511 reviews)
"Front desk service was amazing and love the central location to all the LGBTQ bars and restaurants."
United States
Victor
The price is P5,935
P6,692 total
includes taxes & fees
Nov 8 - Nov 9
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

6. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (560 reviews)
"Super nice amenities - would stay again. Great location"
United States
Nirmeen
The price is P12,697
P19,355 total
includes taxes & fees
Nov 15 - Nov 16
Kasa Little Italy San Diego

7. Stroll to Shore + Mission Blvd: Dog-friendly Home

Stroll to Shore + Mission Blvd: Dog-friendly Home
3.0 star property
Mission Beach
The price is P14,219
P37,920 total
includes taxes & fees
Nov 18 - Nov 19
Stroll to Shore + Mission Blvd: Dog-friendly Home

8. 2 Bedroom Townhome 2 Mins. to the Beach

2 Bedroom Townhome 2 Mins. to the Beach
3.5 star property
Mission Beach
5.8 out of 10, (7 reviews)
"The owner of property cancelled my stay and I can not get anyone to give me a refund. I would appreciate someone getting back to me for this. I will not let it go unsettled. "
United States
Randy
2 Bedroom Townhome 2 Mins. to the Beach

9. Large Group Wellness Retreat w Spa & Gym

Large Group Wellness Retreat w Spa & Gym
3.0 star property
University City
The price is P54,463
P97,121 total
includes taxes & fees
Nov 13 - Nov 14
Large Group Wellness Retreat w Spa & Gym

10. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (240 reviews)
"Wonderful place!"
Canada
Eric
The price is P7,443
P8,481 total
includes taxes & fees
Nov 23 - Nov 24
Kasa Gaslamp Quarter San Diego

11. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is P20,440
P47,123 total
includes taxes & fees
Nov 18 - Nov 19
< 2 Mi to Pacific Beach! Sunny San Diego Escape

12. Rooftop w/ Views: Modern Little Italy Townhome

Rooftop w/ Views: Modern Little Italy Townhome
3.5 star property
Downtown San Diego
10.0 out of 10, Exceptional, (1 review)
Rooftop w/ Views: Modern Little Italy Townhome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top South San Diego Hotel Reviews

Find out more about South San Diego

Search for holiday rentals in South San Diego on Expedia! You can easily find your home rentals, villas, holiday apartments in South San Diego using one of the methods below:

  • View our selection of featured holiday rentals in South San Diego
  • Use the map to find apartments and other holiday homes in the South San Diego neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in South San Diego while they last

Look no further and take a look at our great range of rental properties in South San Diego!