Hotels near Sister James Care Center

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Our top choices for Sister James Care Center hotels

Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton
2.5 star property
2.9 km from Sister James Care Center
9.4 out of 10, Exceptional, (156)
"Great place to stay "
United States
Elizabeth
The price is P7,003
P7,730 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Fairfield Inn & Suites by Marriott Yankton

Comfort Inn Yankton SD

Comfort Inn Yankton SD
2.5 star property
2.8 km from Sister James Care Center
8.8 out of 10, Excellent, (673)
"Affordable with very clean, comfortable rooms, super friendly staff and a nice breakfast. "
United States
Roberta
The price is P5,202
P5,772 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Comfort Inn Yankton SD

Holiday Inn Express & Suites Yankton by IHG

Holiday Inn Express & Suites Yankton by IHG
2.5 star property
3.6 km from Sister James Care Center
9.2 out of 10, Wonderful, (416)
"Yes, clean room "
United States
Evyonne
The price is P5,943
P6,872 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Holiday Inn Express & Suites Yankton by IHG

Best Western Kelly Inn

Best Western Kelly Inn
2.5 star property
5.2 km from Sister James Care Center
8.0 out of 10, Very Good, (651)
"Will stay there again."
United States
Terrence
The price is P5,766
P6,385 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Best Western Kelly Inn

Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
7.7 km from Sister James Care Center
8.8 out of 10, Excellent, (284)
"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
United States
Jessica
The price is P5,534
P5,850 total
includes taxes & fees
Dec 28 - Dec 29
Lewis and Clark Resort

Yankton Inn

Yankton Inn
2.0 star property
5.1 km from Sister James Care Center
7.6 out of 10, Good, (273)
"Clean room, low pet fee, quiet."
United States
Joseph
The price is P5,002
P5,555 total
includes taxes & fees
Dec 28 - Dec 29
Yankton Inn

Econo Lodge Inn & Suites Yankton

Econo Lodge Inn & Suites Yankton
2.0 star property
3.4 km from Sister James Care Center
7.2 out of 10, Good, (709)
"Yes the room was clean staff was great"
United States
John
The price is P4,502
P5,011 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Econo Lodge Inn & Suites Yankton

The Historic Argo Hotel

The Historic Argo Hotel
3.0 star property
17.2 km from Sister James Care Center
The price is P11,122
P12,457 total
includes taxes & fees
Dec 26 - Dec 27
The Historic Argo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Sister James Care Center Hotel Reviews

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Frequently asked questions

What's the area like around Sister James Care Center?
Sister James Care Center is located in Yankton. You'll find 51 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Sister James Care Center?
Comfort Inn Yankton SD is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 1.7 mi (2.8 km) from Sister James Care Center. Other good choices within a few miles include Fairfield Inn & Suites by Marriott Yankton and Econo Lodge Inn & Suites Yankton.
How many hotels will I find close to Sister James Care Center?
Expedia has 51 hotels and other accommodations a few miles from Sister James Care Center.
If I need to cancel the hotel reservation for my stay near Sister James Care Center, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Sister James Care Center.
What can I see and do near Sister James Care Center?
Spend some time wandering around Lewis and Clark Recreation Area, Fantle Memorial Park, and Crockett Park. For cultural attractions near Sister James Care Center, head to Dakota Territorial Museum, G.A.R. Hall, and Riverside Park Amphitheatre. Enjoy nature at Lake Yankton, Westside Park, or Tripp Park.