Seneca Hotels

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Seneca hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
9.6 out of 10, Exceptional, (40)
"Lovely stay! Highly recommend!!!"
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (1006)
"Very beautiful place to stay"
The price is P6,317
P7,841 total
includes taxes & fees
Oct 10 - Oct 11
Lakeside Lodge Clemson

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (645)
"Staff was friendly very clean "
The price is P4,381
P5,385 total
includes taxes & fees
Oct 19 - Oct 20
Quality Inn Seneca Clemson Area US-123

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (775)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
The price is P6,130
P6,743 total
includes taxes & fees
Oct 19 - Oct 20
Tru by Hilton Seneca Clemson

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (702)
"Friendly staff easy check-in. "
The price is P4,138
P4,551 total
includes taxes & fees
Oct 12 - Oct 13
Days Inn by Wyndham Seneca / Clemson Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (194)
"Nice hotel by the lake"
The price is P7,476
P8,224 total
includes taxes & fees
Oct 12 - Oct 13
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (643)
"Great location to downtown Seneca. Very quiet with great workout facility"
The price is P7,165
P7,882 total
includes taxes & fees
Oct 12 - Oct 13
Hampton Inn & Suites Seneca-Clemson Area

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (620)
"Convenient for Clemson visits."
The price is P5,172
P5,689 total
includes taxes & fees
Oct 19 - Oct 20
Best Western Seneca-Clemson

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very Good, (1010)
"Great value and great hotel. We would stay there again. "
The price is P5,616
P6,234 total
includes taxes & fees
Oct 12 - Oct 13
Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very Good, (1002)
"Awesome place to stay"
The price is P5,615
P6,233 total
includes taxes & fees
Oct 16 - Oct 17
Comfort Inn & Suites Clemson - University Area

Days Inn by Wyndham Anderson

2.0 star property
7.6 out of 10, Good, (1009)
"Rooms were clean and staff was very accommodating!"
The price is P3,409
P3,784 total
includes taxes & fees
Oct 12 - Oct 13
Days Inn by Wyndham Anderson

Woodspring Suites Anderson North I-85

2.5 star property
7.2 out of 10, Good, (34)
"This was a new clean facility with nice staff. "
The price is P4,882
P5,419 total
includes taxes & fees
Oct 10 - Oct 11
Woodspring Suites Anderson North I-85

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1004)
"Very nice staff and great place to stay"
Inn @ Clemson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.0 out of 10, Wonderful, (570)
"Good breakfast, clean "
The price is P5,980
P6,638 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (820)
"Clean room | Staff | Parking | Family-friendly"
The price is P4,172
P4,631 total
includes taxes & fees
Oct 12 - Oct 13
Baymont by Wyndham Anderson Clemson

Hilton Garden Inn Anderson

3.0 star property
9.0 out of 10, Wonderful, (650)
"When I got there to check in the front desk worker was very nice and helpful room was nice and clean "
The price is P5,434
P6,032 total
includes taxes & fees
Oct 20 - Oct 21
Hilton Garden Inn Anderson

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (708)
"Room is clean. Bed was comfortable."
The price is P3,923
P4,355 total
includes taxes & fees
Oct 14 - Oct 15
Baymont by Wyndham Easley/Greenville

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (698)
"Great staff, location, comfortable and well maintained property."
The price is P10,953
P12,157 total
includes taxes & fees
Oct 19 - Oct 20
The Shepherd Hotel Downtown Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very Good, (1002)
"Great stay"
The price is P4,693
P5,209 total
includes taxes & fees
Oct 12 - Oct 13
Microtel Inn & Suites by Wyndham Anderson/Clemson

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (880)
"Shopping is good nears around "
The price is P3,483
P3,866 total
includes taxes & fees
Oct 30 - Oct 31
Quality Inn Clemson near University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Keowee Reservoir and Oconee County Library Seneca Branch.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Keowee Reservoir and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Photo by Cindy Keese
Open Photo by Cindy Keese

Top Seneca Hotel Reviews

More cheap stays in Seneca

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Quality Inn Seneca Clemson Area US-123: Features daily, a seasonal outdoor pool, and free self parking. Lakeside Lodge Clemson and Best Western Seneca-Clemson are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 288 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

Explore a world of travel with Expedia

Explore a world of travel with Expedia