Santo Tomé Hotels

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Check prices for these dates

Tonight
Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Santo Tomé hotels

Minibar, in-room safe, blackout drapes, rollaway beds
Hotel Puerto Amarras

Hotel Puerto Amarras

Hotel Puerto Amarras
3.5 star property
Santa Fe
8.0 out of 10, Very Good, (75)
"Good location and recommended spot in the city. Surrounded by water is a beautiful location to stay. The room was a very nice surprise: is huge!! It was a perfect stop over in the road trip!"
United States
Emilio
The price is P5,459
P5,459 total
Dec 28 - Dec 29
Hotel Puerto Amarras
Front of property
Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.2 out of 10, Wonderful, (31)
"Great location and friendly, accommodating staff. "
United States
Michael
The price is P6,064
P6,064 total
Jan 4 - Jan 5, 2026
Maran Suites & Towers - Hotel & Spa
Lobby sitting area
InterTower Hotel

InterTower Hotel

InterTower Hotel
4.0 star property
Santa Fe
8.8 out of 10, Excellent, (213)
"Excelent place to stay."
United States
Angel
The price is P5,629
P5,629 total
Dec 28 - Dec 29
InterTower Hotel
Front of property
Castelar Hotel Santa Fe

Castelar Hotel Santa Fe

Castelar Hotel Santa Fe
3.0 star property
Santa Fe
7.4 out of 10, Good, (92)
"Great area for walking and dining. Friendly and helpful staff. "
Canada
Claude
The price is P3,751
P3,751 total
Dec 25 - Dec 26
Castelar Hotel Santa Fe
Private kitchen
Agustín 1 Apart

Agustín 1 Apart

Agustín 1 Apart
4.0 star property
Parana
9.0 out of 10, Wonderful, (4)
"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."
Brazil
Jose rodrigo kallas
The price is P3,171
P3,171 total
Dec 25 - Dec 26
Agustín 1 Apart
Outdoor pool
Los Silos Hotel

Los Silos Hotel

Los Silos Hotel
4.0 star property
Santa Fe
9.2 out of 10, Wonderful, (28)
"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"
United States
Russell
The price is P6,352
P6,352 total
Dec 28 - Dec 29
Los Silos Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santo Tomé attractions

El Museo Etnografico y Colonial Juan de Garay

You can spend time exploring the galleries in El Museo Etnografico y Colonial Juan de Garay during your travels in Santo Tomé. Experience the area's live music and museums.
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Museo De Arte Contemporaneo

You can spend time studying the exhibits at Museo De Arte Contemporaneo during your travels in Santo Tomé. Experience the area's live music and museums.
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Top Santo Tomé Hotel Reviews

More cheap stays in Santo Tomé

Hostal Santa Fe de la Veracruz

Hostal Santa Fe de la Veracruz

San Martin 2954 Santa Fe Santa Fe
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Frequently asked questions

What's the best place to stay in Santo Tomé?
Hotel de Campo Colon is one of the top choices for your stay based on our traveler data. This hotel offers a full-service spa and free breakfast. Two other choices for your stay in the area are InterTower Hotel and Los Silos Hotel. See all available top hotels, or vacation rentals in Santo Tomé.
If I need to cancel my hotel reservation in Santo Tomé, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santo Tomé.
What's it like to stay in Santo Tomé?
Visitors can enjoy all that Santo Tomé has to offer including its museums. There are 64 hotels and other accommodations in the surrounding area. Find out more about Santo Tomé.
What is there to see in Santo Tomé?
A couple of favorite places to visit are El Museo Etnografico y Colonial Juan de Garay and Museo De Arte Contemporaneo. You'll also find Brigadier General Estanislao Lopez Stadium and Plaza 25 de Mayo in the area. Check out what more to see and do in Expedia's Santo Tomé guide.
What's the weather like in Santo Tomé?
The hottest months are usually January and December with an average temp of 77°F, while the coldest months are July and June with an average of 57°F. Average annual precipitation for Santo Tomé is 48 inches.

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