Santo Domingo Trips (flight + hotel)

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Top hotels in Santo Domingo

Hotel Santo Domingo

Hotel Santo Domingo

3 out of 5
1336 Cra. 16, Santo Domingo, Antioquia
The price is P913 per night from Aug 7 to Aug 8
P913
P913 total
Aug 7 - Aug 8
Hotel Santo Domingo
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

4 out of 5
El Peñol - Guatape Paraje, Vereda Los Naranjos, Guatapé, Antioquia
Fully refundableReserve now, pay when you stay
The price is P9,454 per night from Aug 10 to Aug 11
P9,454
P9,454 total
Aug 10 - Aug 11
9/10 Wonderful! (312 reviews)
"The hotel is very nice, cozy, clean, and the staff is incredible. The breakfast is good, sufficient, and delicious. The food in general is delicious, but we didn't like a couple of dishes we tried. The wings were very ugly, and the chicken tortilla soup was delicious, but I ordered it twice and it ..."

Reviewed on Jul 30, 2025

The Brown, Guatape, Autograph Collection
BubbleSky Glamping Guatapé

BubbleSky Glamping Guatapé

3 out of 5
Guatape - El Anillo 3 kms, Ingresando por la piedra, Guatapé, Colombian Peso
8.8/10 Excellent! (69 reviews)
"It was great just a few things were not quite as expected like it rained all night and it was cold but thats not the places fault. But just certain things"

Reviewed on Jul 26, 2025

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BubbleSky Glamping Guatapé
See all 560 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo vacation package cost?
You can grab a vacation package to this destination on Expedia. But how much your vacation to Santo Domingo costs will depend on the length of stay, hotel choice and season.
What are the cheapest months to go to Santo Domingo?
April, June and September are the best times to search for cheap Santo Domingo vacation packages. Opting to travel in quieter periods means you can typically find reduced prices on accommodations and flights.
How many days is enough for Santo Domingo?
Typically, a handful of days is enough to tick off the main attractions during your Santo Domingo vacation. However, if you prefer to have some time to relax or go on day trips, consider extending your trip.
How to find the best Santo Domingo package deals?
Landing a cheap Santo Domingo package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tweak your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santo Domingo vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking flights and hotels individually. Better still, you can personalize your Santo Domingo escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Santo Domingo?
If you're considering a spontaneous Santo Domingo getaway, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to Santo Domingo?

  1. Pick the ideal time to travel: Your schedule, favorite season and the type of weather you enjoy can all influence your decision on when to visit Santo Domingo.
  2. Figure out your budget: Ensure you have enough money to cover everything from transportation and dining out to flights and experiences. Your accommodations will likely be the largest expense during your trip to Santo Domingo.
  3. Determine how many days away: Start by listing all the activities and sights you'd like to get to in Santo Domingo. Then, estimate how long you'll need at each, as well as any travel time.
  4. Combine your accommodations and airfare: After you've nailed down your travel dates and duration, lock in the perfect Santo Domingo vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.