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Santo Domingo Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Santo Domingo vacation rentals

A covered seating area with two white plastic chairs and a small table, surrounded by neatly trimmed hedges and a palm tree.

1. Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
The price is P4,568
P5,025 total
includes taxes & fees
Oct 11 - Oct 12
Casa Little Italy
A kitchen with a marble island, wooden stools, a white door, and a window with curtains.

2. la casa de Matias

la casa de Matias
2.0 star property
Volcán
The price is P2,509
P2,760 total
includes taxes & fees
Oct 3 - Oct 4
la casa de Matias
A view from a room with a glass door to a patio area. The patio has a tiled floor and a white chair. Palm trees and a building with a red roof are visible in the background.

3. Perla Pacifico

Perla Pacifico
3.5 star property
Puerto Armuelles
The price is P3,113
P3,425 total
includes taxes & fees
Oct 2 - Oct 3
Perla Pacifico
A room with a dark-colored sofa set, a matching armchair, and a door with a light blue frame.

4. Urban Loft Nueva California

Urban Loft Nueva California
2.0 star property
Nueva California
The price is P2,807
P3,088 total
includes taxes & fees
Oct 7 - Oct 8
Urban Loft Nueva California
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Hotel Reviews

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

10/10 Excellent
"Una buena propiedad para alejarse de todo y encontrarse con la naturaleza. Muy buen ambiente y hospitalidad. El personal se portó de maravillas, y fueron muy servicial. Tomé la opción de desayuno incluidos, y muy sabrosos. Me quedé 2 noches en Septiembre 2026. Regresaría de nuevo."
John 2-night trip
Posted 8 days ago
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Find out more about Santo Domingo

Search for holiday rentals in Santo Domingo on Expedia! You can easily find your home rentals, villas, holiday apartments in Santo Domingo using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santo Domingo!

Frequently asked questions

Are there vacation rentals in Santo Domingo?

Yes, we offer vacation rentals near popular local attractions in Santo Domingo, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals in Santo Domingo?

La casa de Matias: This vacation home rental outside of Santo Domingo offers a garden and free WiFi to help you feel comfortable in your new surroundings.

What can I see and do in Santo Domingo?

While you're exploring the area, Las Cavernas de Corredores and Canyon Macho de Monte are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll also find Arte Cruz Volcán.

What are vacation rentals like in Santo Domingo?

Vacation rentals are private accommodations you can reserve for a short or long stay in Santo Domingo. Vacation rentals offer extras such as laundry facilities and kitchens so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for family trips.