Boutique Hotels in Santo Domingo, Santo Domingo

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santo Domingo Boutique Hotels

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Santo Domingo boutique hotels

Exterior
Casas del XVI

Casas del XVI

Casas del XVI
5.0 star property
Zona Colonial
9.4 out of 10, Exceptional, (230)
"Everything was amazing "
United States
Lesterlin
The price is P18,505
P23,687 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Casas del XVI
Outdoor pool, sun loungers
Billini Hotel, Historic Luxury

Billini Hotel, Historic Luxury

Billini Hotel, Historic Luxury
4.5 star property
Zona Colonial
9.2 out of 10, Wonderful, (806)
"Great "
United States
Steven
The price is P12,161
P15,566 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Billini Hotel, Historic Luxury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santo Domingo Hotel Reviews

Hodelpa Caribe Colonial

Hodelpa Caribe Colonial

10/10 Excellent
"Staff were wonderful "
Wanda 1-night trip
Posted 5 days ago
Hodelpa Caribe Colonial

Frequently asked questions

What's the best boutique accommodation in Santo Domingo?
Casas del XVI is a favorite hotel with our travelers looking for a stylish accommodation, and features 20 guestrooms, free parking, and massages. Billini Hotel, Historic Luxury and Casa Conde Hotel Boutique are other boutique-style choices.
What's there to see and do in Santo Domingo?
Visitors speak positively about this destination's breathtaking beach views, interesting historical sites, and major shopping area. Experience the cultural highlights around Santo Domingo with a visit to Museum of History and Geography, Alcazar de Colon, and Larimar Museum. While you're here, you might also want to consider exploring Calle El Conde, Santa Maria la Menor Cathedral, and Calle Las Damas.
What kind of weather should I plan for when I travel to Santo Domingo?
Getting an idea of what to expect from the weather in Santo Domingo will help you enjoy your stay to the fullest. The hottest months are usually September and August with an average temp of 80°F, while the coldest months are February and January with an average of 75°F. Average annual precipitation for Santo Domingo is 42 inches.
What's the best way to get to my boutique hotel in Santo Domingo?
You have a few options for traveling to and around Santo Domingo. The closest major airport is Santo Domingo (JBQ-La Isabela Intl.), which is located 8.6 mi (13.9 km) away, but Las Americas Intl. Airport (SDQ) may also be an option. Take advantage of metro transit at Coronel Rafael Tomas Fernandez Station, Mauricio Baez Station, and Casandra Damiron Station.