Hotels near Santee National Wildlife Refuge

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Dec 24 - Dec 25
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Dec 25 - Dec 26
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Dec 26 - Dec 28
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Our top choices for Santee National Wildlife Refuge hotels

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
7 km from Santee National Wildlife Refuge
9.8 out of 10, Exceptional, (1001)
"Staff very friendly, room super clean"
United States
Karine
The price is P7,105
P7,887 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Fairfield Inn & Suites by Marriott Santee
Free breakfast
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
7 km from Santee National Wildlife Refuge
9.6 out of 10, Exceptional, (1002)
"Rooms are clean, friendly staff and easy to get off and back on the highway. "
United States
Michelle
The price is P7,904
P8,774 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn Santee-I-95
Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
7.2 km from Santee National Wildlife Refuge
9.2 out of 10, Wonderful, (649)
"Nice place to stay"
Canada
Tanya
The price is P6,061
P6,727 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru By Hilton Santee
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
7 km from Santee National Wildlife Refuge
8.8 out of 10, Excellent, (1000)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is P6,953
P7,717 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Plus Santee Inn
Exterior
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
7.2 km from Santee National Wildlife Refuge
8.2 out of 10, Very Good, (977)
"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is P6,355
P7,054 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Santee by IHG
Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
7.2 km from Santee National Wildlife Refuge
8.0 out of 10, Very Good, (1410)
"Very friendly staff. "
United States
Ramil
The price is P4,707
P5,225 total
includes taxes & fees
Dec 25 - Dec 26
Baymont by Wyndham Santee
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
7.2 km from Santee National Wildlife Refuge
8.0 out of 10, Very Good, (1003)
"Staff was pleasant and helpful with restaurant information, room clean. "
United States
Mark
The price is P6,040
P6,704 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, free WiFi, bed sheets
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
7.1 km from Santee National Wildlife Refuge
7.0 out of 10, Good, (678)
"The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. "
United States
Alice
The price is P3,590
P3,984 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Travelodge by Wyndham Santee
Lobby
Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
7 km from Santee National Wildlife Refuge
6.8 out of 10, (441)
"The staff was very friendly and helpful. Room was clean and beds were so comfortable. "
United States
Kathy
The price is P4,413
P4,899 total
includes taxes & fees
Dec 25 - Dec 26
Super 8 by Wyndham Santee
Exterior
Red Roof Inn Santee

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
7 km from Santee National Wildlife Refuge
6.6 out of 10, (638)
"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is P4,119
P4,572 total
includes taxes & fees
Dec 25 - Dec 26
Red Roof Inn Santee
Free daily full breakfast
Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
6.9 km from Santee National Wildlife Refuge
6.0 out of 10, (456)
"exellent service"
United States
Mirjana
The price is P3,201
P3,879 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn & Suites Santee I-95
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Santee

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
7.1 km from Santee National Wildlife Refuge
6.4 out of 10, (309)
"Last minute arrangements stay was quiet and peaceful "
United States
Iasia
The price is P3,724
P4,133 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Econo Lodge Santee
Lake view
Bells Marina & Resort

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
19.5 km from Santee National Wildlife Refuge
8.6 out of 10, Excellent, (80)
"Room was clean with a beautiful view of the Lake."
United States
Melanie
The price is P3,879
P4,306 total
includes taxes & fees
Dec 25 - Dec 26
Bells Marina & Resort
1 bedroom
Starlight Stays

Starlight Stays

Starlight Stays
2.5 star property
19.8 km from Santee National Wildlife Refuge
7.0 out of 10, Good, (7)
"It was nice for the area "
United States
Kendrell
The price is P3,623
P4,022 total
includes taxes & fees
Dec 28 - Dec 29
Starlight Stays
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee National Wildlife Refuge Hotel Reviews

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Great gene was awesome "
Robert 1-night trip
Posted 7 days ago
Hampton Inn Santee-I-95

Hotels near other Santee National Wildlife Refuge attractions

Pine Island

Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks.
See properties

Santee Indian Mound and Fort Watson Site

You can enjoy some culture when you stop by Santee Indian Mound and Fort Watson Site in Summerton. While you're in the area, wander around the parks.
See properties

Frequently asked questions

What's the area like around Santee National Wildlife Refuge?
Santee National Wildlife Refuge is located in a welcoming area of Summerton known for its array of dining options and golfing. You'll find 132 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Santee National Wildlife Refuge?
Tru By Hilton Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 4.4 mi (7.2 km) from Santee National Wildlife Refuge. Other good choices within a few miles include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee.
How many hotels will I be able to find near Santee National Wildlife Refuge?
Expedia has 132 hotels and other accommodations a few miles from Santee National Wildlife Refuge.
If I need to cancel the hotel reservation for my stay near Santee National Wildlife Refuge, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review the best deals available near Santee National Wildlife Refuge.