Hotels in Santana from P3,242 for 2026 - Fully Refundable Options

A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

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Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

Santana

"Very friendly and every time smiling service. They are well trained, but also hard treated by the boss. For example he never smiled or said hello. You feel this like a guest, too. We had a room on poolside. They rooms are very modern and comfy, but in the 3 rooms we went in had big mold patches everywhere. Everyday we had to pay our bills, like the ones for dinner. We asked for paying at checkout, they said it’s impossible etc. At the same moment our friends who sit next to us and can speak...

Daniel

P7,564

P14,462 total

includes taxes & fees

Aug 22 - Aug 23

2. Residencial Aeroporto

São Tomé

P3,962

P4,556 total

includes taxes & fees

Aug 22 - Aug 23

3. Casa de Ferias

São Tomé

Lars Roland

P1,173

P4,533 total

includes taxes & fees

Sep 20 - Sep 21

4. Agua Leve

São Tomé

P3,101

P3,566 total

includes taxes & fees

Aug 22 - Aug 23

5. Guest House Quinta Natural

Trindade

P2,283

P3,620 total

includes taxes & fees

Aug 22 - Aug 23

6. SH Boutique Hotel

São Tomé

Simon Peter

P3,665

P4,214 total

includes taxes & fees

Sep 4 - Sep 5

7. Hotel Kenito

São Tomé

Ada

P5,018

P5,770 total

includes taxes & fees

Aug 24 - Aug 25

8. Pestana São Tomé

Vila Maria

alexander

P18,041

P20,747 total

includes taxes & fees

Aug 24 - Aug 25

9. Welfare Agroturismo

Trindade

P4,313

P4,960 total

includes taxes & fees

Sep 21 - Sep 22

10. Residêncial Tamarindos

Guadalupe

Maria

P2,819

P3,242 total

includes taxes & fees

Aug 22 - Aug 23

11. Omali São Tomé – Principe Collection

São Tomé

Kysha

P11,863

P13,945 total

includes taxes & fees

Sep 7 - Sep 8

12. Hotel Central

São Tomé

Mohammad

P3,115

P3,582 total

includes taxes & fees

Aug 28 - Aug 29

13. Hotel Praia

São Tomé

Jonathan

P10,698

P12,302 total

includes taxes & fees

Sep 15 - Sep 16

14. Alojamento Santos Silva

São Tomé

P19,733

P22,692 total

includes taxes & fees

Aug 22 - Aug 23

15. CAMPISMO PRAIA GRANDE

Malanza

John

P3,045

P3,501 total

includes taxes & fees

Sep 12 - Sep 13

16. Emoyeni Gardens Hotel

Vila Maria

P9,563

P10,998 total

includes taxes & fees

Aug 31 - Sep 1

17. Praia Accommodation

São Tomé

Daniel

P7,116

P8,184 total

includes taxes & fees

Aug 23 - Aug 24

18. Miramar São Tomé

São Tomé

sandra

P10,649

P12,246 total

includes taxes & fees

Aug 24 - Aug 25

19. Hotel Vitória

São Tomé

Anonymous traveler

P3,759

P4,322 total

includes taxes & fees

Sep 19 - Sep 20

20. Nour Apartments

São Tomé

P3,045

P3,501 total

includes taxes & fees

Aug 22 - Aug 23

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Learn more about Santana

Venture to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana

A wooden bench overlooking a calm sea with a small island in the distance and lush greenery on the right.

Top Santana Hotel Reviews

More cheap stays in Santana

Nour Apartments

Rua 3 de Fevereiro São Tomé

P3,045

P3,501 total

Aug 22 - Aug 23

includes taxes & fees

Hotel Kenito

Campo de Milho São Tomé

P5,018

P5,770 total

Aug 24 - Aug 25

includes taxes & fees

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza

P5,787

P6,655 total

Sep 3 - Sep 4

includes taxes & fees

8.8/10 Excellent! (27 reviews)

Sweet Guest House

Vila Dolores n. 087 São Tomé

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Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé

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Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome

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Frequently asked questions

Where is the best place to stay in Santana?

Based on our traveler data, Roça Santo António Ecolodge Hotel is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Pool and Beach Villa in Santana is another good choice for your stay. See all available top hotels, or vacation rentals in Santana.

What are some of the best vacation rentals that Santana has to offer?

Alojamento Santos Silva: This vacation home rental outside of Santana offers an outdoor pool, a garden, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave, and kitchenware. See all vacation rentals in Santana.

If I need to cancel my hotel reservation in Santana, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.

What's the best hotel for families in Santana?

Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Attractions in the area like Cloçon Téla Chocolate Factory are also fun for the whole family. Find more child-friendly accommodations in Santana.

What are some accommodations with pools in Santana?

Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. View all hotels with pools in Santana.

What's it like to stay in Santana?

Those traveling to Santana are sure to enjoy the sights to see and things to do. In Santana, there are 4 hotels and other accommodations to choose from. Find out more about Santana.

What are the top places to visit in Santana?

Places to visit in the wider area include Estadio Nacional 12 de Julho, São Sebastião Museum, and Pico São Tomé. You'll also find Paroquia da Santissima Trindade and Palácio dos Congressos in the area. Check out what more to see and do in Expedia's Santana guide.

What's the weather like in Santana?

The hottest months are usually March and April with an average temp of 82°F, while the coldest months are July and August with an average of 77°F. The rainiest months in Santana are November, October, December, and April, with each month seeing an average of 10 inches of rainfall.

Santana Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santana

Check prices for these dates

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Star rating

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Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

2. Residencial Aeroporto

3. Casa de Ferias

4. Agua Leve

5. Guest House Quinta Natural

6. SH Boutique Hotel

7. Hotel Kenito

8. Pestana São Tomé

9. Welfare Agroturismo

10. Residêncial Tamarindos

11. Omali São Tomé – Principe Collection

12. Hotel Central

13. Hotel Praia

14. Alojamento Santos Silva

15. CAMPISMO PRAIA GRANDE

16. Emoyeni Gardens Hotel

17. Praia Accommodation

18. Miramar São Tomé

19. Hotel Vitória

20. Nour Apartments

Learn more about Santana

Top Santana Hotel Reviews

More cheap stays in Santana

Nour Apartments

Hotel Kenito

Praia Inhame Eco-Lodge

Sweet Guest House

Inviting 10 Bed Apartment in Sao Tome

Pousada Roça São João dos Angolares

Frequently asked questions

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