Santa Lucia Vacation Rentals

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Check prices for these dates

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Santa Lucia vacation rentals

Memory foam beds, in-room safe, individually decorated
Aenea Superior Inn

Townhouse in Rome City Centre

Aenea Superior Inn
9.6 out of 10, Exceptional, (1005)
"Excellent and convenient stay"
United States
Giulia
The price is P8,487
P10,166 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Aenea Superior Inn
Memory foam beds, minibar, in-room safe, desk
Excellence Suite

Townhouse in Rome City Centre

Excellence Suite
8.4 out of 10, Very Good, (1045)
"Great location, Affordable, clean, nice staff. We had a very convenient stay. "
United States
Pourandokht
The price is P4,637
P5,930 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Excellence Suite
Exterior detail
hu Roma Camping In Town

Camping in Gianicolense Suburb

hu Roma Camping In Town
8.2 out of 10, Very Good, (2404)
"Friendly staff."
United States
Alondra
The price is P3,037
P3,755 total
includes taxes & fees
Jan 9 - Jan 10, 2026
hu Roma Camping In Town
Property entrance
San Pietro Boutique Rooms

Townhouse in Rome City Centre

San Pietro Boutique Rooms
10.0 out of 10, Exceptional, (915)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
San Pietro Boutique Rooms
Private kitchen
Tritone Top House

Townhouse in Rome City Centre

Tritone Top House
8.4 out of 10, Very Good, (628)
"Great location , room was a good size "
Australia
Rachel
The price is P5,319
P6,542 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Tritone Top House
Minibar, in-room safe, individually decorated, individually furnished
Palazzetto Trevi

Townhouse in Rome City Centre

Palazzetto Trevi
9.4 out of 10, Exceptional, (224)
"The room was super clean and the TV had Netflix and Amazon, which was fab!"
United Kingdom
Natasha
Palazzetto Trevi
Free minibar, in-room safe, blackout drapes, soundproofing
Villa della Fonte - Trastevere

Townhouse in Rome City Centre

Villa della Fonte - Trastevere
9.8 out of 10, Exceptional, (159)
"The staff was the best great loacation would definitely stay again"
United States
andrew
Villa della Fonte - Trastevere
Rooftop terrace
Giuditta in Trastevere

Townhouse in Rome City Centre

Giuditta in Trastevere
9.6 out of 10, Exceptional, (267)
"Clean room, good location and fantastic staff "
United States
alberto
Giuditta in Trastevere
Living area
Ara di Marte Suites

Townhouse in Rome City Centre

Ara di Marte Suites
9.2 out of 10, Wonderful, (104)
"Loved the location and great staff"
United States
Earnell
The price is P7,638
P9,232 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Ara di Marte Suites
In-room safe, blackout drapes, soundproofing, free WiFi
Camere IV Miglio

Townhouse in Cinecitta

Camere IV Miglio
9.6 out of 10, Exceptional, (12)
"Yes was very nice and quiet."
Canada
Ali Hassan
The price is P8,770
P10,339 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Camere IV Miglio
Interior
Lungotevere Suite

Residence in Portuense

Lungotevere Suite
8.8 out of 10, Excellent, (326)
"Laundry was excellent ! Everything was great "
Canada
Andreina Maria
The price is P4,682
P5,980 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Lungotevere Suite
Front of property
Tullia e Prisca Relais

Townhouse in Rome City Centre

Tullia e Prisca Relais
9.2 out of 10, Wonderful, (575)
"Really nice staff and great room. We really enjoyed our stay!"
United States
Hannah
The price is P6,733
P8,236 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Tullia e Prisca Relais
Exterior
Numa Rome Trastevere

Aparthotel in Gianicolense

Numa Rome Trastevere
9.2 out of 10, Wonderful, (60)
"Clean room, great amenities, good location"
Germany
Efthimios-Enias
The price is P5,303
P6,663 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Numa Rome Trastevere
Bar (on property)
Relais Orso

Townhouse in Rome City Centre

Relais Orso
8.6 out of 10, Excellent, (451)
" Cute area. Enjoyed staying there for a few days "
United States
Rebecca
Relais Orso
1 bedroom, premium bedding, in-room safe, desk
Capricci Romani

Townhouse in Rome City Centre

Capricci Romani
9.4 out of 10, Exceptional, (361)
"Really enjoyed the location and staff. Breakfast was amazing. "
United States
Raquel
Capricci Romani
View from property
Colosseo Panoramic Rooms

Townhouse in Rome City Centre

Colosseo Panoramic Rooms
9.4 out of 10, Exceptional, (476)
"Loved the amazing location and the friendly staff "
United States
Melissa
Colosseo Panoramic Rooms
Egyptian cotton sheets, premium bedding, minibar, in-room safe
Navona Central Suites

Townhouse in Rome City Centre

Navona Central Suites
9.0 out of 10, Wonderful, (273)
"We had a great stay!"
United States
Christopher
Navona Central Suites
Down comforters, minibar, in-room safe, laptop workspace
Cavour LR Collection

Townhouse in Rome City Centre

Cavour LR Collection
8.8 out of 10, Excellent, (103)
"Cute room, love the balcony. Would come back again"
United States
Rebecca
The price is P6,012
P7,443 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Cavour LR Collection
Staircase
Piazza di Spagna Prestige

Townhouse in Rome City Centre

Piazza di Spagna Prestige
9.0 out of 10, Wonderful, (932)
"Perfecto! Great location and decor! "
Canada
Deborah
Piazza di Spagna Prestige
Frette Italian sheets, premium bedding, memory foam beds, minibar
Star Vatican Rooms

Townhouse in Rome City Centre

Star Vatican Rooms
8.0 out of 10, Very Good, (594)
"Great place , clean and close to main attractions "
United States
Leonel
Star Vatican Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Lucia Hotel Reviews

UNA Hotels Decò Roma

UNA Hotels Decò Roma

10/10 Excellent
"We had a very good stay and the hotel is very conveniently located."
Fernando 2-night trip
Posted 1 day ago
UNA Hotels Decò Roma

Find out more about Santa Lucia

Search for holiday rentals in Santa Lucia on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Lucia using one of the methods below:

  • View our selection of featured holiday rentals in Santa Lucia
  • Use the map to find apartments and other holiday homes in the Santa Lucia neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Lucia while they last

Look no further and take a look at our great range of rental properties in Santa Lucia!

Frequently asked questions

Can I find a vacation rental in Santa Lucia?

Yes, there are vacation rentals near popular sights in Santa Lucia, or you can choose a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santa Lucia has to offer?

Oriana Homèl Roma: This vacation home rental outside of Santa Lucia is in the city center and equipped with air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Santa Lucia?

Explore the area and family-friendly sights such as Bioparco di Roma, or get out into nature at a spot like Villa Borghese. While in the area, you can also visit popular places like Trevi Fountain and Colosseum.

What’s a vacation rental in Santa Lucia like?

Vacation rentals are private properties where you can stay for a few weeks or just a few days in Santa Lucia. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so you'll have all the comforts of home. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great option for families.