Santa Isabel Hotels

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Isabel hotels

Hotel Araiza Mexicali

4.0 star property
8.6 out of 10, Excellent, (1601)
"Great place to vacay "
The price is P6,136
P6,934 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Araiza Mexicali

Real Inn Mexicali

4.0 star property
8.2 out of 10, Very Good, (1460)
"Great place "
The price is P4,550
P5,141 total
includes taxes & fees
Oct 13 - Oct 14
Real Inn Mexicali

One Mexicali

3.0 star property
7.8 out of 10, Good, (1002)
"Todo excelente "
The price is P4,071
P4,600 total
includes taxes & fees
Oct 7 - Oct 8
One Mexicali

Hotel Siesta Real

3.0 star property
8.2 out of 10, Very Good, (841)
"Nice and friendly place "
The price is P4,322
P4,884 total
includes taxes & fees
Oct 5 - Oct 6
Hotel Siesta Real

City Express Plus by Marriott Mexicali

3.5 star property
8.6 out of 10, Excellent, (884)
"Good location"
The price is P4,244
P4,796 total
includes taxes & fees
Oct 5 - Oct 6
City Express Plus by Marriott Mexicali

Sleep Inn Mexicali

3.0 star property
8.2 out of 10, Very Good, (1002)
"They have good breakfast "
The price is P3,831
P4,636 total
includes taxes & fees
Oct 17 - Oct 18
Sleep Inn Mexicali

Hotel Lucerna Mexicali

4.0 star property
9.2 out of 10, Wonderful, (1377)
"Great stay! "
The price is P5,556
P6,278 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Lucerna Mexicali

Azteca de Oro Mexicali

3.0 star property
7.6 out of 10, Good, (403)
"Exelente"
The price is P2,024
P2,287 total
includes taxes & fees
Oct 6 - Oct 7
Azteca de Oro Mexicali

Holiday Inn Express & Suites Mexicali by IHG

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Great hotel, location and service"
The price is P7,140
P8,069 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express & Suites Mexicali by IHG

Extended Suites Mexicali Cataviña

3.0 star property
8.0 out of 10, Very Good, (2096)
"Love the location, very clean rooms and very safe "
Extended Suites Mexicali Cataviña

Fairfield Inn & Suites by Marriott Mexicali

2.5 star property
9.4 out of 10, Exceptional, (1000)
"The room was clean, lots of restaurants and breakfast was delicious. "
The price is P6,106
P6,900 total
includes taxes & fees
Oct 19 - Oct 20
Fairfield Inn & Suites by Marriott Mexicali

Calafia Hotel

3.5 star property
8.2 out of 10, Very Good, (1000)
"Love the area, the staff were super friendly, the rooms were great!"
The price is P4,681
P5,289 total
includes taxes & fees
Nov 2 - Nov 3
Calafia Hotel

City Express by Marriott Mexicali

3.0 star property
8.2 out of 10, Very Good, (1001)
"Out stay was Great!!!"
The price is P4,614
P5,213 total
includes taxes & fees
Oct 5 - Oct 6
City Express by Marriott Mexicali

Fiesta Inn Mexicali

3.5 star property
8.2 out of 10, Very Good, (1003)
"Great Hotel "
The price is P4,648
P5,252 total
includes taxes & fees
Oct 12 - Oct 13
Fiesta Inn Mexicali

City Express Junior by Marriott Mexicali

3.0 star property
7.8 out of 10, Good, (1001)
"- staff accommodated my needs friendly friendly and place was quiet enough to relax "
The price is P3,950
P4,463 total
includes taxes & fees
Oct 5 - Oct 6
City Express Junior by Marriott Mexicali

Hotel Colonial Mexicali

3.5 star property
7.8 out of 10, Good, (1018)
"It was affordable, the room was clean and in great condition"
The price is P4,688
P5,297 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Colonial Mexicali

Courtyard by Marriott Mexicali

3.0 star property
9.4 out of 10, Exceptional, (753)
"Very clean and new hotel "
The price is P6,043
P6,829 total
includes taxes & fees
Oct 17 - Oct 18
Courtyard by Marriott Mexicali

Motel Cies

3.0 star property
9.2 out of 10, Wonderful, (47)
"Great place to stay awesome service "
The price is P3,120
P3,588 total
includes taxes & fees
Nov 3 - Nov 4
Motel Cies

Hotel Cosmos Don Carlos

3.0 star property
8.0 out of 10, Very Good, (471)
"Great stay!"
Hotel Cosmos Don Carlos

Hotel Hacienda del Indio

3.0 star property
7.2 out of 10, Good, (123)
"The room was clean and the parking was safe"
The price is P1,873
P2,267 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Hacienda del Indio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Near an Attraction

Palenque Fex

Palenque Fex

Learn about the events happening at Palenque Fex during your trip to Mexicali. While in this family-friendly area, you can savor the top-notch restaurants.

Hospital de la Familia

Hospital de la Familia

Though Hospital de la Familia might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

Top Santa Isabel Hotel Reviews

More cheap stays in Santa Isabel

More cheap stays in Santa Isabel

Frequently asked questions

What's the best place for a stay in Santa Isabel?

Hotel Lucerna Mexicali, located 7.5 mi (12.1 km) from the heart of Santa Isabel, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Hotel Araiza Mexicali and Real Inn Mexicali. See all available top hotels, or vacation rentals in Santa Isabel.

If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.

Where can I learn more about changing or cancelling my trip to Santa Isabel?

To access more information about changing or cancelling your trip to Santa Isabel, click here.

What is staying in Santa Isabel like?

Visitors to Santa Isabel are sure to find plenty to explore and enjoy. There are 71 hotels and other accommodations in the surrounding area. Find out more about Santa Isabel.

What is there to see in Santa Isabel?

Places to visit in the wider area include Gran Plaza Outlets, Mexicali Border Port I, and Plaza Comercial La Cachanilla. You'll also find Eagles Nest Stadium and Imperial Valley Mall in the area. Check out what more to see and do in Expedia's Santa Isabel guide.

What's the seasonal weather like in Santa Isabel?

The hottest months are usually July and August with an average temp of 93°F, while the coldest months are December and January with an average of 61°F. Average annual precipitation for Santa Isabel is 3 inches.

Explore a world of travel with Expedia

Explore a world of travel with Expedia