Santa Cruz Trips (flight + hotel)

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
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Historical Center

7 out of top 10 points of interest in this area

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Top hotels in Santa Cruz

Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is P14,575 per night from Sep 5 to Sep 6
P14,575
P16,033 total
Sep 5 - Sep 6
includes taxes & fees
9.4/10 Exceptional! (1,033 reviews)
"Fantastic location with great walkable places all over"

Reviewed on Aug 4, 2025

Hotel Rey Alfonso X
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is P8,217 per night from Aug 19 to Aug 20
P8,217
P9,039 total
Aug 19 - Aug 20
includes taxes & fees
9.6/10 Exceptional! (1,007 reviews)
"Our stay at Hotel Amadeus was wonderful The air-conditioning worked beautifully after hot days outside. It was wonderful to be able to cool down in our room. The rooftop is amazing. It just keeps on going. The service was outstanding. They were so helpful and kind and lovely people to deal with. ..."

Reviewed on Aug 8, 2025

Hotel Amadeus Sevilla
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is P13,913 per night from Sep 5 to Sep 6
P13,913
P15,304 total
Sep 5 - Sep 6
includes taxes & fees
9.6/10 Exceptional! (1,523 reviews)
Great
"Always fantastic at Fernando III, but strange they dont take Amarican Express and least of 15 sunbeds at the poolarea was broken."

Reviewed on Aug 10, 2025

Hotel Fernando III
See all 414 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or traveling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz vacation?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our vacation packages today.
Can I choose my airline with a Santa Cruz Expedia vacation package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organizing your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Popular places to visit

Giralda Tower which includes a castle and heritage architecture

Giralda Tower

This ornate belfry has an interesting past; before being one of the Cathedral's towers, it was a minaret.

Giralda Tower

Things to do

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

P2,171
per adult
92% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
a narrow dirt road leading to a town in Spain

White Villages & Ronda Day Trip from Seville

P5,197
per adult
92% of travellers recommend
White Villages & Ronda Day Trip from Seville
Boat Trip "Los Rincones del Guadalquivir"

Boat Trip "Los Rincones del Guadalquivir"

P1,645
per adult
82% of travellers recommend
Boat Trip "Los Rincones del Guadalquivir"
See all activities in Seville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.