Santa Cruz Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 2 - Aug 3
Tomorrow
Aug 3 - Aug 4
Next weekend
Aug 8 - Aug 10
In two weeks
Aug 15 - Aug 17

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

La Casita de mi Abuela
Exterior

La Casita de mi Abuela

3.0 star property
6.8 out of 10, (3)
"Excelente lugar para disfrutar la naturaleza, la atención es súper y las vistas geniales. Súper recomendado "
La Casita de mi Abuela
Oro Andino Lodge
1 bedroom, free WiFi

Oro Andino Lodge

2.5 star property
The price is P8,926
P8,926 total
Aug 10 - Aug 11
Oro Andino Lodge
GRAN HOTEL
Exterior

GRAN HOTEL

2.0 star property
The price is P1,534
P1,534 total
Aug 4 - Aug 5
GRAN HOTEL
hostal kactus
Bathroom

hostal kactus

1.0 star property
The price is P730
P730 total
Aug 4 - Aug 5
hostal kactus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Cruz

Venture to sights like Huascaren National Park and Punta Union as you discover Santa Cruz.

See all hotels in Santa Cruz
Photo by nevin xavier
Open Photo by nevin xavier

Top Santa Cruz Hotel Reviews

Frequently asked questions

What's the best place to stay in Santa Cruz?

Santa Cruz Eco Lodge is one of the top choices for your stay based on our traveler data. This lodge offers free breakfast and free parking. Two other choices for your visit to the area are Oro Andino Lodge and La Casita de mi Abuela. See all available top hotels, or vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To access more information about rescheduling or cancelling your trip to Santa Cruz, head over to our customer service page.

What is the favorite LGBTQ-friendly place to stay in Santa Cruz?

Santa Cruz Eco Lodge is a top LGBTQ-friendly lodge that features free breakfast and free parking. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

How is it to stay in Santa Cruz?

Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 14 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.

What should I see while I'm in Santa Cruz?

A couple of favorite places to visit are Huascaren National Park and Punta Union. You'll also find Lake Paron and Cañón del Pato in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually August and July with an average temp of 53°F, while the coldest months are July and August with an average of 53°F. The rainiest months in Santa Cruz are March, January, December, and February, with each month seeing an average of 10 inches of rainfall.