Photo by nevin xavier

Santa Cruz Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

Oro Andino Lodge
2.5 star property
6.0 out of 10, (2)
"Nos encantó nuestra estadía. Desde que llegamos, nos hicieron sentir como en casa. El lodge tiene una energía muy bonita, rodeado de naturaleza y con detalles cuidados en cada rincón. El personal es súper amable. Definitivamente queremos volver."
Mexico
YULI ARIELA
The price is P9,575
P9,575 total
Dec 3 - Dec 4
Oro Andino Lodge
GRAN HOTEL
2.0 star property
GRAN HOTEL
La Casita de mi Abuela
3.0 star property
6.8 out of 10, (3)
"Excelente lugar para disfrutar la naturaleza, la atención es súper y las vistas geniales. Súper recomendado "
Mexico
Cristian
La Casita de mi Abuela
TULLPA RUMY
3.0 star property
The price is P2,977
P2,977 total
Dec 3 - Dec 4
TULLPA RUMY
hostal kactus
1.0 star property
The price is P1,567
P1,567 total
Dec 3 - Dec 4
hostal kactus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Venture to sights like Huascaren National Park and Punta Union as you discover Santa Cruz.

Team posing for the epic shot in Punta union pass in the Peruvian Andes
Photo by nevin xavier
Open Photo by nevin xavier

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What's the best place to stay in Santa Cruz?
Santa Cruz Eco Lodge is one of the top choices for your stay based on our traveler data. This lodge offers free breakfast and free parking. Two other choices for your visit to the area are GRAN HOTEL and Oro Andino Lodge. See all available top hotels, or vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is the favorite LGBTQ-friendly place to stay in Santa Cruz?
Santa Cruz Eco Lodge is a top LGBTQ-friendly lodge that features free breakfast and free parking. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 14 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.
What should I see while I'm in Santa Cruz?
A couple of favorite places to visit are Huascaren National Park and Punta Union. You'll also find Lake Paron and Cañón del Pato in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually August and July with an average temp of 53°F, while the coldest months are July and August with an average of 53°F. The rainiest months in Santa Cruz are March, January, December, and February, with each month seeing an average of 10 inches of rainfall.