Sant'Onofrio Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 1 - Dec 2
Tomorrow
Dec 2 - Dec 3
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Vacation Rentals in Sant'Onofrio

In-room safe, laptop workspace, soundproofing, free WiFi
Nora's Suites

Nora's Suites

Politeama
10.0 out of 10, Exceptional, (12)
"Excellent location surrounded by many great restaurants , the breakfast was amazing at the café on the same street. The room was comfortable and well-maintained, the service and communication with the staff was excellent. Highly recommended. "
Canada
ALEXANDR
The price is P3,894
P4,828 total
includes taxes & fees
Dec 2 - Dec 3
Nora's Suites
Terrace/patio
Marbela Apartments & Suites

Marbela Apartments & Suites

3.0 star property
Libertà
8.6 out of 10, Excellent, (74)
"Locating the property was easy. There was a great sushi spot within walking distance called Mill, I believe. Checkin went well. The apartment spelled of cigarettes and odor remover. Lots of space. Flat bed and pillows. Overall it provided what we needed. "
United States
Koren
The price is P6,148
P7,307 total
includes taxes & fees
Dec 2 - Dec 3
Marbela Apartments & Suites
Front of property
Casta Diva Luxury Apartments

Casta Diva Luxury Apartments

Palermo Historical Center
8.8 out of 10, Excellent, (3)
"Really loved this apartment. It’s right on the main street, Via Maqueda, so it’s convenient for everything. The apartment is so spacious, very clean, and properly decorated with excellent amenities."
United States
Garry
The price is P6,792
P10,055 total
includes taxes & fees
Dec 4 - Dec 5
Casta Diva Luxury Apartments
Seasonal outdoor pool
Apartments Porta di Castro

Apartments Porta di Castro

Palermo Historical Center
10.0 out of 10, Exceptional, (2)
The price is P8,345
P9,724 total
includes taxes & fees
Dec 9 - Dec 10
Apartments Porta di Castro
Fridge
Residence Hotel Gloria

Residence Hotel Gloria

3.0 star property
Montegrappa-Santa Rosalia
7.8 out of 10, Good, (63)
" "
Italy
GABRIELLA
Residence Hotel Gloria
Lobby
Palermo Central Rooms

Palermo Central Rooms

Oreto - Stazione
10.0 out of 10, Exceptional, (1)
The price is P3,648
P4,556 total
includes taxes & fees
Dec 3 - Dec 4
Palermo Central Rooms
Exterior detail
Giulio Cesare 14

Giulio Cesare 14

Oreto - Stazione
8.6 out of 10, Excellent, (67)
"Fantastic staff - very helpful and great location."
Australia
ROBERT
The price is P3,486
P5,875 total
includes taxes & fees
Dec 3 - Dec 4
Giulio Cesare 14
Private kitchen
Casta Diva Fervore Apartments

Casta Diva Fervore Apartments

Politeama
10.0 out of 10, Exceptional, (7)
"Loved the location just off the Lolli train stop. Also very cute bars and restaurants and grocery store nearby. Was the perfect spot for my 2 day stay in Palermo. Appreciate that the place was clean and updated. "
United States
Ronda
The price is P5,218
P6,284 total
includes taxes & fees
Dec 3 - Dec 4
Casta Diva Fervore Apartments
Exterior
Real Umberto Apartments by WonderfuI Italy

Real Umberto Apartments by WonderfuI Italy

Palermo Historical Center
Real Umberto Apartments by WonderfuI Italy
Balcony
Appartamenti Pellegrino

Appartamenti Pellegrino

Palermo Historical Center
10.0 out of 10, Exceptional, (1)
"Very helpful team, clean and well appointed suite!"
Canada
Ginalee
Appartamenti Pellegrino
Individually decorated, laptop workspace, iron/ironing board
Palazzo Amazigh

Palazzo Amazigh

Palermo Historical Center
8.0 out of 10, Very Good, (4)
"Property was very nice. Large apartment with washer. Lift in the building. Walkable to all the sights, nice shopping and rest/bars. Would stay again."
United States
Shirley
The price is P7,477
P11,013 total
includes taxes & fees
Dec 28 - Dec 29
Palazzo Amazigh
View from room
Into Palermo Rooms al Massimo

Into Palermo Rooms al Massimo

Palermo Historical Center
The price is P7,109
P8,364 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Into Palermo Rooms al Massimo
Seasonal outdoor pool, pool umbrellas, sun loungers
Casette di Calzata

Casette di Calzata

Campofelice di Roccella
8.8 out of 10, Excellent, (20)
"Great stay"
United States
Georgy
Casette di Calzata
Exterior
Gattopardo Apartments by LAGO Design

Gattopardo Apartments by LAGO Design

Palermo Historical Center
9.6 out of 10, Exceptional, (5)
"Great experience. I would recommend this place. It is huge beautifully furnished apartment."
United States
Olga
Gattopardo Apartments by LAGO Design
Beach
Villa Scaduto Residence

Villa Scaduto Residence

3.0 star property
Bagheria
7.8 out of 10, Good, (59)
"Nice spot for the night. Beds were deceptively comfortably. Restaurants attached is very good. "
Canada
Kevin William
The price is P4,018
P4,719 total
includes taxes & fees
Dec 4 - Dec 5
Villa Scaduto Residence
City view from property
Palazzo Falcone Apartments

Palazzo Falcone Apartments

Politeama
The price is P6,232
P9,779 total
includes taxes & fees
Dec 2 - Dec 3
Palazzo Falcone Apartments
1 bedroom, free WiFi
Palazzo Gregorietti Boutique Apartments

Palazzo Gregorietti Boutique Apartments

Politeama
10.0 out of 10, Exceptional, (2)
"A great apartment, close to restaurants and sightseeing"
United Kingdom
Sarah
The price is P5,946
P12,525 total
includes taxes & fees
Dec 2 - Dec 3
Palazzo Gregorietti Boutique Apartments
Exterior
Sicily Bed' House

Sicily Bed' House

Palermo Historical Center
The price is P4,507
P5,501 total
includes taxes & fees
Dec 2 - Dec 3
Sicily Bed' House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Sant'Onofrio Hotel Reviews

Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro

10/10 Excellent
"Friendly and helpful staff, fantastic breakfast good to have a balcony "
Allessandra 2-night trip
Posted 2 days ago
Mercure Hotel Palermo Centro

Find out more about Sant'Onofrio

Search for holiday rentals in Sant'Onofrio on Expedia! You can easily find your home rentals, villas, holiday apartments in Sant'Onofrio using one of the methods below:

  • View our selection of featured holiday rentals in Sant'Onofrio
  • Use the map to find apartments and other holiday homes in the Sant'Onofrio neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Sant'Onofrio while they last

Look no further and take a look at our great range of rental properties in Sant'Onofrio!

Frequently asked questions

Are there vacation rentals in Sant'Onofrio?

Yes, there are vacation rentals near popular attractions in Sant'Onofrio, or you can select a more secluded option if you'd like a relaxing place to stay.

How many vacation rentals will I find in Sant'Onofrio?

With 5 Expedia vacation rentals, you're sure to find just the right place for your Sant'Onofrio stay.

What’s there to see and do in Sant'Onofrio?

Explore the area and family-friendly sights such as Madonna Annunciate, or get out into nature at a spot like Sant'Elia Beach. In the larger area, you’ll find Church and Convent of Saint Mary of Jesus and Church St. Nicholas of Bari.

What’s a vacation rental in Sant'Onofrio like?

Vacation rentals are privately owned properties you can stay in for a few weeks or just a few days in Sant'Onofrio. Vacation rentals feature extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.