San Luis Vacation Rentals

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Check prices for these dates

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for San Luis vacation rentals

Front of property
La trinidad

Houseboat in Guatapé

La trinidad
3.5 star property
9.4 out of 10, Exceptional, (30)
"Great place to stay and real reasonable for a glamping trip as a couple!"
United States
George
La trinidad
Living area
KABINE

Chalet in El Peñol

KABINE
3.0 star property
10.0 out of 10, Exceptional, (2)
"Genial"
Colombia
Daniel
The price is P9,600
P9,600 total
Jan 14 - Jan 15, 2026
KABINE
Exterior
Ecoedén Glamping

Cabin in Guatapé

Ecoedén Glamping
3.0 star property
10.0 out of 10, Exceptional, (11)
"The host and staff were friendly and attentive. The view was incredible "
United States
Williiam
Ecoedén Glamping
Minibar, individually furnished, free WiFi, bed sheets
Cardinal Glamping

Cabin in Guatapé

Cardinal Glamping
3.5 star property
Cardinal Glamping
Bathroom
Nativa Ecohotel - Laguna de San Diego

Cabin in Samaná

Nativa Ecohotel - Laguna de San Diego
2.0 star property
The price is P6,743
P6,743 total
Jan 1 - Jan 2, 2026
Nativa Ecohotel - Laguna de San Diego
43-inch flat-screen TV with digital channels, streaming services
GRETEL CHALETS SUIZO

Cabin in Guatapé

GRETEL CHALETS SUIZO
3.5 star property
10.0 out of 10, Exceptional, (7)
"Beautiful place and ideal for a unforgettable moment!! Great service!!"
United States
Azaias
The price is P8,995
P8,995 total
Jan 18 - Jan 19, 2026
GRETEL CHALETS SUIZO
Heated floors
Finca hotel Sendero del rio

Aparthotel in San Rafael

Finca hotel Sendero del rio
2.5 star property
8.8 out of 10, Excellent, (3)
"The family who runs this former finca turned hotel is so kind, responsive and accommodating. I had a perfect visit!"
United States
Mary
The price is P30,558
P30,558 total
Jan 12 - Jan 13, 2026
Finca hotel Sendero del rio
Private kitchen
Casa García Rent Home

Apartment in Guatapé

Casa García Rent Home
3.5 star property
7.2 out of 10, Good, (7)
"Besides the lovely family hosting a more beautiful location with the vistas would be hard to imagine the only challenges to drive based on weather conditions, and the host is more gracious to also meet us on the main street and have a follow him"
United States
Stephen
Casa García Rent Home
Private kitchen
Jardines del Lago

Apartment in Guatapé

Jardines del Lago
2.0 star property
The price is P1,933
P2,946 total
Jan 12 - Jan 13, 2026
Jardines del Lago
Front of property
Hotel Mito Guatapé

Cabin in Guatapé

Hotel Mito Guatapé
3.0 star property
The price is P4,600
P4,600 total
Jan 31 - Feb 1, 2026
Hotel Mito Guatapé
Terrace/patio
Luum Glamping by Roots Rentals

Cabin in Marinilla

Luum Glamping by Roots Rentals
2.5 star property
8.0 out of 10, Very Good, (2)
Luum Glamping by Roots Rentals
Free WiFi
Samadhi Glamping

Chalet in El Penol

Samadhi Glamping
2.0 star property
The price is P3,458
P3,458 total
Jan 12 - Jan 13, 2026
Samadhi Glamping
Exterior
MONTECIELO HOSTING GUATAPE

Apartment in El Peñol

MONTECIELO HOSTING GUATAPE
4.0 star property
8.6 out of 10, Excellent, (10)
"Bad internet- no TV or phones for 3 of 4 days. 50 stairs to climb to get to apartment. The best view in Penol"
United States
Joe
The price is P4,584
P4,584 total
Jan 28 - Jan 29, 2026
MONTECIELO HOSTING GUATAPE
Minibar, laptop workspace, free WiFi
Sotavento Cabañas

Cabin in Guatapé

Sotavento Cabañas
3.0 star property
9.8 out of 10, Exceptional, (52)
"Food great,very accommodating, great massages and the luxury cabin was beautiful "
Canada
Derrick
The price is P10,858
P10,858 total
Jan 4 - Jan 5, 2026
Sotavento Cabañas
Porch
La Martinera Malecón

Apartment in Guatapé

La Martinera Malecón
3.0 star property
7.4 out of 10, Good, (10)
"The property has a nice view of the lake and it is conveniently located in front of the large "GUATAPE" letters for pictures. The staff is extremely courteous and helpful. There is no lobby at this particular location."
United States
Marco
The price is P1,740
P2,762 total
Jan 12 - Jan 13, 2026
La Martinera Malecón
Living area
Villa Mediterranea

Aparthotel in Puerto Triunfo

Villa Mediterranea
2.0 star property
8.0 out of 10, Very Good, (5)
"New apartment, everything was clean and bed was super comfortable, I’ll recommend staying here"
United States
Mayra
The price is P3,364
P3,835 total
Jan 23 - Jan 24, 2026
Villa Mediterranea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Hotel Reviews

EL NIDO HOTEL GUATAPE

EL NIDO HOTEL GUATAPE

10/10 Excellent
"This hotel is a gem! Beautiful views the cabin was very clean and the staff very helpful and friendly. Will definitely go back to this place totally love it."
Henry 1-night trip
Posted 1 day ago
EL NIDO HOTEL GUATAPE

Find out more about San Luis

Search for holiday rentals in San Luis on Expedia! You can easily find your home rentals, villas, holiday apartments in San Luis using one of the methods below:

  • View our selection of featured holiday rentals in San Luis
  • Use the map to find apartments and other holiday homes in the San Luis neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in San Luis while they last

Look no further and take a look at our great range of rental properties in San Luis!

Frequently asked questions

Can I find vacation rentals in San Luis?

Yes, we have vacation rentals close to top points of interest in San Luis, or you can choose a more remote option if you want a relaxing place to stay.

What are some of the best vacation rentals in San Luis?

Finca San Fernando El peñol-Guatape: This vacation home rental near San Luis has a Smart TV and WiFi to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms and a kitchen with a fridge.

What’s there to see and do in San Luis?

While exploring the area, visit family-friendly sights like Parque Comfama, or get outside and enjoy nature at La Planta Waterfall. In the larger area, you’ll find El Balseadero Nature Park and Rock of Guatapé.

What’s a vacation rental in San Luis like?

A vacation rental is a private property you can book for a few weeks or just a few days in San Luis. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family gatherings.