San Isidro Trips (flight + hotel)

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to P 3,118 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
Ayala Center showing modern architecture

Cartagena Walled City

3 out of top 10 points of interest in this area

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Cartagena Cathedral while in the area.

Find hotels in Cartagena Walled City

Top hotels in San Isidro

Hilton Cartagena

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito, Cartagena
Fully refundableReserve now, pay when you stay
The price is P7,973 per night from Aug 9 to Aug 10
P7,973
P7,973 total
Aug 9 - Aug 10
9/10 Wonderful! (1,095 reviews)
"Great service Orlando and he’s bar crew was amazing we will recommend him and the hotel to our friends and family"

Reviewed on Jul 14, 2025

Hilton Cartagena
InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

4 out of 5
Bocagrande Carrera 1 No. 5-01, Cartagena, Bolivar
Fully refundable
The price is P11,454 per night from Aug 18 to Aug 19
P11,454
P11,454 total
Aug 18 - Aug 19
9.2/10 Wonderful! (1,107 reviews)
"One of the best hotels in Bocagrande. Friendly staff. Great views of the ocean"

Reviewed on Jul 16, 2025

InterContinental Cartagena De Indias by IHG
Hyatt Regency Cartagena

Hyatt Regency Cartagena

4.5 out of 5
Carrera 1 No 12-118, Cartagena, CO
Fully refundableReserve now, pay when you stay
The price is P10,675 per night from Jul 29 to Jul 30
P10,675
P10,675 total
Jul 29 - Jul 30
9.2/10 Wonderful! (1,331 reviews)
"Nice vacation, friendly staff"

Reviewed on Jul 17, 2025

Hyatt Regency Cartagena
See all 3,673 properties in San Isidro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Isidro vacation package cost?
Our San Isidro vacation packages, which begin at just , are the perfect way to save big. Select your favorite hotels, flights and more to create a personalized escape.
How do I get a cheap travel package to San Isidro?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you a pretty penny too. A San Isidro vacation package makes it a cinch to organize your ideal trip. With more than 550 airlines throughout the world to select from, finding flights that fit your busy schedule will be no sweat. Not only that, we've got over 1,000,000 hotels globally to pick from. Now that's what you call choice. No matter who you are, Expedia will help show you the world.
Where should I stay in San Isidro?
Most visitors who travel to San Isidro include San Felipe de Barajas Castle and San Pedro Claver Church and Convent on their bucket lists. Why not select a hotel right near these main attractions?
How far in advance should I book my San Isidro vacation?
Be rewarded with the widest variety at the lowest prices by booking your trip to San Isidro early. Air carriers typically release flight tickets anywhere up to 12 months in advance, so start locking things in as soon as you can. That being said, Expedia is constantly working to give you the best deals around, so it's always a good time to book your dream vacation!
What does an Expedia San Isidro travel package include?
It comes down to what sort of escape you have in the works. San Isidro vacation deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your style and budget. You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a San Isidro travel package?
A travel package can be tailored to your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Hotels, rental cars and flights — come up with a combination that suits your plans.
Can I choose my airline with a San Isidro Expedia vacation package?
With a vacation package, you're the boss. Whether you're hoping to fly to San Isidro in coach or first class, simply select from the available airline options. Expedia has access to more than 550 airline partners throughout the world.
If I'm not able to travel, can I cancel my San Isidro vacation package?
Whether it's your hotel or flight, yes, you can cancel or amend it. Locked in your San Isidro vacation package in the last 24 hours? You may be able to make changes or cancellations at no cost. For older bookings, you may be charged a fee by your airline, hotel or car rental company. For more details, take a look at our Customer Service Portal. We'll help you each step of the way.

Popular places to visit

Blanca Beach

Blanca Beach

If a restful vacation is part of your travel plans, Blanca Beach might be the perfect place to seek out during your trip to Cartagena.

Blanca Beach
Isla Grande Beach

Isla Grande Beach

Why not spend a carefree afternoon at Isla Grande Beach during your travels in Rosario Islands? You can seek out the snorkeling spots in this relaxing area.

Isla Grande Beach

Playa de Punta Arena

If a restful vacation is part of your travel plans, Playa de Punta Arena might be the perfect place to seek out during your trip to Cartagena.

Playa de Punta Arena

Things to do

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

P3,383
per adult
80% of travellers recommend
The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat
Picture 1 for Activity Cartagena: 5-Stop Rosario Islands Tour with Lunch & Entries

Cartagena: 5 Must-See Rosario Islands Highlights with Lunch

P3,665
per adult
76% of travellers recommend
Cartagena: 5 Must-See Rosario Islands Highlights with Lunch
Tour of the Rosario Islands, Cartagena

Tour of the Rosario Islands, Cartagena

P5,638
per adult
86% of travellers recommend
Tour of the Rosario Islands, Cartagena
See all activities in Cartagena
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.