San Francisco Trips (flight + hotel)

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    Better together

    Save up to P 3,118 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco

Top hotels in San Francisco

Oro Verde Guayaquil
Oro Verde Guayaquil
5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is P5,073 per night from Aug 1 to Aug 2
P5,073
P5,721 total
Aug 1 - Aug 2
9.4/10 Exceptional! (1,005 reviews)
"I love the hotel it’s so clean it smells delicious in all places even the pool, great staff and excellent environment super recommended"

Reviewed on Jul 6, 2025

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana
Wyndham Guayaquil Puerto Santa Ana
4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is P6,899 per night from Jul 18 to Jul 19
P6,899
P7,730 total
Jul 18 - Jul 19
9.2/10 Wonderful! (1,005 reviews)
"Great service and attention."

Reviewed on Jul 6, 2025

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG
Holiday Inn Guayaquil Airport by IHG
3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
Fully refundable
The price is P4,689 per night from Jul 18 to Jul 19
P4,689
P5,299 total
Jul 18 - Jul 19
9.2/10 Wonderful! (1,002 reviews)
"I recommend"

Reviewed on Jul 6, 2025

Holiday Inn Guayaquil Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Francisco vacation package cost?
From as little as . Yes, you read that right. Our San Francisco vacation packages are a simple way to make your dollars go much further. Bundle your hotels, flights and car rentals and discover this popular destination.
How do I get a cheap travel package to San Francisco?
Browse and lock in everything all in one place with our San Francisco vacation packages. We have deals on hotels, flights, tours and more that'll keep your wallet happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 properties globally to select from, you'll have endless opportunities to mix and match as you please.
How far in advance should I book my San Francisco vacation?
Search Expedia to compare airfares as soon as you know your travel dates. In many cases, you can purchase a ticket up to a year before departure. If you don't see your preferred carrier, or you have to book last minute, don't worry. The lowest prices to San Francisco occasionally appear within weeks of departure.
What does an Expedia San Francisco travel package include?
That depends on what sort of getaway you're contemplating. San Francisco travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that works for you! You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a San Francisco travel package?
So many places to travel to, so many things to see. With a package, you'll be able to cross more of them off your list. Combine your hotels, rental cars and flights and see how much you save.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, you can. We have more than 550 partner airlines worldwide, so fly with the carrier that best suits your travel preferences.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Certainly, and we're here to help. You may be able to cancel and rebook your San Francisco vacation package at no cost if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, browse our Customer Service Portal for more information.

Popular places to visit

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.