Downtown South San Francisco

San Francisco

Photo by Catherine Edejer-McCormick

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
The price is P8,051 per night from Sep 21 to Sep 22
P8,051
P11,820 total
Sep 21 - Sep 22
includes taxes & fees
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (6,819 reviews)
"I liked its location."

Reviewed on Sep 16, 2025

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is P7,257 per night from Sep 21 to Sep 22
P7,257
P8,541 total
Sep 21 - Sep 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
8.8/10 Excellent! (4,567 reviews)
"The booking was a quick and easy process and the hotel was easily accessible, has good parking and everything is nearby! The room was clean and updated and the view was amazing! Will stay again!"

Reviewed on Sep 16, 2025

Holiday Inn Golden Gateway by IHG
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
The price is P10,706 per night from Sep 25 to Sep 26
P10,706
P15,275 total
Sep 25 - Sep 26
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,876 reviews)
Great hotel, but expensive and added costs
"This is one of my favorite hotels. Although the parking prices are absolutely ridiculous and for my two nights stay there was an extra fee of $94 charged by the hotel for destination fees."

Reviewed on Sep 15, 2025

Hyatt Regency San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
The price is P7,692 per night from Oct 5 to Oct 6
P7,692
P9,053 total
Oct 5 - Oct 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,766 reviews)
"Everything was super nice"

Reviewed on Sep 15, 2025

Hilton San Francisco Financial District
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
The price is P5,748 per night from Sep 21 to Sep 22
P5,748
P6,536 total
Sep 21 - Sep 22
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (2,179 reviews)
"Clean"

Reviewed on Sep 16, 2025

Crowne Plaza San Francisco Airport by IHG
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
The price is P7,435 per night from Sep 21 to Sep 22
P7,435
P8,751 total
Sep 21 - Sep 22
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,589 reviews)
"A block or two away from the Transamerica building. Walkable distance to Chinatown, Little Italy, and the Ferry Terminal. They do not validate parking at 1 Embarcadero like their messaging system says. Rooms are kind of small, but not too terrible. Beds are super comfortable. Staff is amazing and ..."

Reviewed on Sep 15, 2025

Club Quarters Hotel in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

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Excelsior

While Excelsior isn't home to many top sights, Cow Palace and San Bruno Mountain State Park are some notable places to visit nearby.

Excelsior
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Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
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Mission District

Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like San Francisco Public Library.

Mission District
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Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Letterform Archive are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
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Sunset District

Travelers choose Sunset District for its pristine beaches. Hop aboard the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop and check out top sights like Ocean Beach.

Sunset District
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Mission Bay

While you're in Mission Bay, take in top sights like Chase Center or Lefty O'Doul Bridge, and hop on the metro to see more the city at Mission Rock Station or UCSF/Chase Center Stop.

Mission Bay


Downtown South San Francisco