San Domino Trips (flight + hotel)

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    Save up to P 3,118 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Top hotels in San Domino

Eden

Eden

3 out of 5
Via Garibaldi 1 - Isolotto Di San Domino, Tremiti Islands, FG
Fully refundableReserve now, pay when you stay
The price is P8,245 per night from Aug 31 to Sep 1
P8,245
P9,069 total
Aug 31 - Sep 1
includes taxes & fees
8.2/10 Very Good! (219 reviews)
"Friendly staff, great location. Katia at Reception was amazing"

Reviewed on Aug 2, 2025

Eden
Hotel Kyrie Isole Tremiti

Hotel Kyrie Isole Tremiti

3 out of 5
Isole Tremiti, San Domino, Tremiti Islands, FG
Fully refundableReserve now, pay when you stay
8/10 Very Good! (127 reviews)
"The hotel is in a very good location, walking distance (10-15mins) from the main square with shops, restaurants and a grocery shop. The hotel is in a beautiful scenery, up on the top of the island, with complimentary (free for guests of the hotel) frequent and very convenient shuttle transport from ..."

Reviewed on Jul 13, 2024

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Hotel Kyrie Isole Tremiti
L'ISOLA DEI SAPORI BOUTIQUE HOTEL

L'ISOLA DEI SAPORI BOUTIQUE HOTEL

STRADA PROVINCIALE 41 KM 34,00, Cagnano Varano, FG
9.2/10 Wonderful! (15 reviews)
"The owner was so kind and friendly."

Reviewed on Jul 26, 2025

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L'ISOLA DEI SAPORI BOUTIQUE HOTEL
See all 25 properties in San Domino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cala Matano

If a restful vacation is part of your travel plans, Cala Matano might be the perfect place to seek out during your trip to Tremiti Islands. Wander the waterfront and parks while you're in the area.

Cala Matano

Violet Cave

Explore the great outdoors at Violet Cave, a lovely green space in Tremiti Islands. Wander the beaches and waterfront while you're in the area.

Violet Cave

Frequently asked questions

How much does a San Domino vacation package cost?
Browse and book everything in one place with our San Domino vacation packages, which start from just . Handpick the hotels and flights that suit your plans. Then, add on a couple of sightseeing activities to cap off your unique adventure.
How do I get a cheap travel package to San Domino?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a few dollars too. A San Domino vacation package makes it a cinch to organize the perfect trip. With more than 550 airlines throughout the world to select from, finding flights that fit your busy schedule won't be a hassle. On top of that, we have over 1,000,000 hotel options globally to select from. Now that's choice! Whatever your budget, Expedia will help show you the world.
How far in advance should I book my San Domino vacation?
While prices change from time to time, we generally advise booking your seats as early as possible. Most international fares are available on Expedia up to a year in advance. If circumstances have left you booking last minute, you may still get lucky. Low prices to San Domino sometimes occur just weeks before departure.
What does an Expedia San Domino travel package include?
It comes down to what you want. If you're traveling by yourself, you might decide to bundle hotels and flights. Bringing the entire family to San Domino? A travel package including flights, hotels and rental cars might be a better fit. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking a San Domino travel package?
You'll score terrific savings when you combine your hotels, flights and rental cars into a travel package. Plus, booking everything together just makes things easier. So why waste time or money? Whether you're putting together a luxury city stay with your love or a budget family adventure, browse our package deals today.
Can I choose my airline with a San Domino Expedia vacation package?
Yes, of course. We have more than 550 airline partners worldwide, so opt for the carrier that matches your budget needs.
If I'm not able to travel, can I cancel my San Domino vacation package?
Don't worry if you're rethinking your San Domino vacation package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that happens. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.