A coastal town with a pier, boats, and a hillside with buildings.

Hotels with Spa in Pythagorio, Samos

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Check availability on Pythagorio Hotels with Spa

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Pythagorio hotels with a spa

A pool area with steps leading into the water, a bench, and a stone wall.

1. Casa Cook Samos

Casa Cook Samos
5.0 star property
Samos
9.4 out of 10, Exceptional, (151 reviews)
  • cleanliness
    Immerse in a beachfront boutique escape with 4 specialized treatment rooms and daily aromatherapy spa services for complete renewal.
The price is P14,655
P17,123 total
includes taxes & fees
Oct 28 - Oct 29
Casa Cook Samos
A modern outdoor terrace with a pool, seating, and a view of a coastal town.

2. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
5.0 star property
Samos
The price is P9,950
P11,968 total
includes taxes & fees
Oct 30 - Oct 31
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
A spacious lobby with a marble floor, white sofas, and potted plants.

3. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
4.0 star property
Samos
9.2 out of 10, Wonderful, (37 reviews)
  • cleanliness
    Serene beachfront escape with two outdoor pools and an on-site spa offering rejuvenating treatments in scenic surroundings.
The price is P5,493
P6,730 total
includes taxes & fees
Oct 29 - Oct 30
Samian Mare Hotel Suites & Spa
A reception area with two curved reception desks, a laptop, potted plants, and a wooden cabinet in the background.

4. Erato by Samian Mare

Erato by Samian Mare
4.0 star property
Samos
9.0 out of 10, Wonderful, (20 reviews)
  • cleanliness
    Discover tranquil waterfront wellness at this eco-certified spa retreat, featuring couples' treatment rooms and traditional Turkish baths.
The price is P7,843
P8,806 total
includes taxes & fees
Nov 10 - Nov 11
Erato by Samian Mare
A hotel reception area with a large wall clock, a television, and a reception desk.

5. Aegeon

Aegeon
3.0 star property
Samos
8.0 out of 10, Very good, (33 reviews)
  • cleanliness
    Unwind at this island hotel with tranquil spa treatments, including massage services in 2 treatment rooms and a relaxing Turkish bath.
The price is P4,032
P4,773 total
includes taxes & fees
Oct 28 - Oct 29
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Pythagorio

Pool
Breakfast included

Top Pythagorio Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Check out the historical sites and museums in Pythagorio—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort.
How many spa hotels are there in Pythagorio?
Among Expedia's 74 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion, and Glicorisa Beach. If you have extra time while you're in the area, you might want to stop by Tunnel of Eupalinos and Potakaki beach.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.