Photo by Mike McClain

Puxico Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 4 - Aug 5
Tomorrow
Aug 5 - Aug 6
This weekend
Aug 8 - Aug 10
Next weekend
Aug 15 - Aug 17

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Puxico hotels

Holiday Inn Poplar Bluff by IHG
Enjoy a drink at the bar, where a variety of beverages are available for service.

Holiday Inn Poplar Bluff by IHG

3.0 star property
8.8 out of 10, Excellent, (667)
"Very clean and comfortable property close to dining options. Would definitely stay again "
The price is P6,023
P6,805 total
includes taxes & fees
Sep 4 - Sep 5
Holiday Inn Poplar Bluff by IHG
Dexter Inn
Situated alongside a commercial building, this location offers easy access to local shops and restaurants.

Dexter Inn

2.5 star property
6.8 out of 10, (307)
"I always stay here when I’m in town. Great place"
The price is P3,729
P4,187 total
includes taxes & fees
Sep 4 - Sep 5
Dexter Inn
Fairfield Inn & Suites by Marriott Poplar Bluff
Relax in the spacious lobby with a stone fireplace, comfortable seating, and a large window.

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (784)
"Excellent choice for a stopping point for group of friends traveling through poplar bluff."
The price is P5,679
P6,416 total
includes taxes & fees
Sep 4 - Sep 5
Fairfield Inn & Suites by Marriott Poplar Bluff
Super 8 by Wyndham Poplar Bluff Missouri
Relax in a spacious room with a large bed, a framed historic landmark print, and convenient bedside amenities.

Super 8 by Wyndham Poplar Bluff Missouri

2.0 star property
6.6 out of 10, (590)
"It was a great stay"
The price is P3,462
P3,911 total
includes taxes & fees
Aug 10 - Aug 11
Super 8 by Wyndham Poplar Bluff Missouri
Hampton Inn Poplar Bluff
Relax in the serene patio area surrounded by lush greenery and a charming gazebo.

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (748)
"Excellent property, great location. "
The price is P5,636
P6,311 total
includes taxes & fees
Aug 17 - Aug 18
Hampton Inn Poplar Bluff
Drury Inn & Suites Poplar Bluff
Relax in the spacious lobby with a reception desk, seating area, and large windows.

Drury Inn & Suites Poplar Bluff

3.0 star property
9.2 out of 10, Wonderful, (890)
"The staff at this property was EXCELLENT!! "
The price is P5,467
P6,175 total
includes taxes & fees
Aug 17 - Aug 18
Drury Inn & Suites Poplar Bluff
Econo Lodge Dexter
Cozy retreat with a comfortable bed, dining table, and sofa, featuring a traditional layout and a beautiful painting above the bed.

Econo Lodge Dexter

2.0 star property
6.8 out of 10, (238)
"Rough parking lot, sparse lobby, ok for one night on a trip, not a vacation spot"
The price is P3,169
P3,558 total
includes taxes & fees
Sep 4 - Sep 5
Econo Lodge Dexter
Comfort Inn Poplar Bluff North
Welcome to our hotel lobby, featuring a reception desk, comfortable seating area, fireplace, and staircase.

Comfort Inn Poplar Bluff North

2.5 star property
7.8 out of 10, Good, (376)
"Comfortable beds, very clean"
The price is P5,243
P5,923 total
includes taxes & fees
Sep 4 - Sep 5
Comfort Inn Poplar Bluff North
Motel 6 Poplar Bluff, MO
Relax in a stylish space with a seating area, kitchenette, and reception desk, offering a view of the outdoors.

Motel 6 Poplar Bluff, MO

2.0 star property
7.8 out of 10, Good, (1012)
"Great place for what we needed."
The price is P4,532
P4,780 total
includes taxes & fees
Aug 7 - Aug 8
Motel 6 Poplar Bluff, MO
Travelodge by Wyndham Dexter
Classic diner interior with checkered floor, booths, and counter area.

Travelodge by Wyndham Dexter

2.0 star property
7.4 out of 10, Good, (365)
"A nice property just off the beaten path. "
The price is P6,165
P6,923 total
includes taxes & fees
Aug 7 - Aug 8
Travelodge by Wyndham Dexter
OYO Hickory House Inn
1 bedroom, desk, iron/ironing board, free WiFi

OYO Hickory House Inn

2.5 star property
5.4 out of 10, (121)
"It was affordable and clean"
The price is P2,545
P3,235 total
includes taxes & fees
Sep 2 - Sep 3
OYO Hickory House Inn
EC Reed's Mercantile and Hotel
Relax in a serene bedroom with a large bed, flat-screen TV, and stylish bedside tables.

EC Reed's Mercantile and Hotel

3.0 star property
9.6 out of 10, Exceptional, (75)
"Great, clean room and the restaurant attached was delicious- best breakfast! "
EC Reed's Mercantile and Hotel
Lake Wappapello
Situated in a secluded forest, this cabin offers a simple, functional space with a metal roof and a single window.

Lake Wappapello

2.0 star property
The price is P7,917
P8,350 total
includes taxes & fees
Sep 4 - Sep 5
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"We always try to stay at Hampton Inn when we travel. Staff always kind and professional, rooms alway nice and clean, and breakfast always good."
Dolores 1-night trip
Posted 3 days ago
Hampton Inn Poplar Bluff

Frequently asked questions

What's the best place for a stay in Puxico?

Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.

If I need to cancel my hotel reservation in Puxico, will I receive a refund?

Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.

Where can I learn more about changing or cancelling my trip to Puxico?

To find more details about picking new dates or cancelling your trip to Puxico, click here.

What are some hotels with pools in Puxico?

Drury Inn & Suites Poplar Bluff: Features an indoor pool, an outdoor pool, and free buffet breakfast. Hampton Inn Poplar Bluff Mo and Holiday Inn Poplar Bluff, an IHG Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Puxico.

What is staying in Puxico like?

Travelers to Puxico will find plenty to explore and enjoy. There are 48 hotels and other accommodations in the surrounding area. Find out more about Puxico.

What is there to see in Puxico?

A couple of favorite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Check out what more to see and do in Expedia's Puxico guide.

What's the seasonal weather like in Puxico?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Puxico is 59 inches.