Hotels in Puxico from P3,629 for 2026 - Fully Refundable Options

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

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Our top choices for Puxico hotels

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

1. Hampton Inn By Hilton Dexter

Dexter

Bryan

P6,130

P6,945 total

includes taxes & fees

Oct 25 - Oct 26

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Nancy

P6,087

P6,877 total

includes taxes & fees

Oct 18 - Oct 19

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

3. Hampton Inn Poplar Bluff

Poplar Bluff

Rhonda

P5,714

P6,398 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

An indoor swimming pool with a clear view of the outside through large windows.

4. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Dean

P5,905

P6,671 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

5. Econo Lodge Dexter

Dexter

Herman

P3,203

P3,629 total

includes taxes & fees

Nov 11 - Nov 12

A diner with booth seating, a checkered floor, and a counter with a cash register.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

6. Travelodge by Wyndham Dexter

Dexter

Steven

P5,428

P6,150 total

includes taxes & fees

Nov 1 - Nov 2

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

7. Dexter Inn

Dexter

Edward

P4,335

P4,911 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

8. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

Nathan

P5,277

P5,962 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

A motel with a prominent '66' sign, large windows, and a flat roof.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

9. Motel 6 Poplar Bluff, MO

Poplar Bluff

Cindy

P4,467

P5,001 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

A bathroom with a bathtub, toilet, and a shower curtain.

10. OYO Hickory House Inn

Dexter

DIEGO

P3,463

P4,269 total

includes taxes & fees

Oct 25 - Oct 26

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel lobby with a coffee station, seating area, and a television screen.

11. Comfort Inn Poplar Bluff North

Poplar Bluff

Muhammad

P4,651

P5,255 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A two-story motel with a covered parking area and a bench outside.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

12. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

Diana

P4,218

P4,766 total

includes taxes & fees

Oct 18 - Oct 19

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A calm lake with a wooden dock and a forested island in the distance.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

13. Lake Wappapello

Williamsville

Tonya

P5,654

P5,963 total

includes taxes & fees

Oct 13 - Oct 14

A living room with a blue wall, a fireplace, a sofa, and a chair.

A brick building with a sign reading "Mercantile & Hotel".

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A bar area with stools and a counter where a bartender is serving drinks.

14. EC Reed's Mercantile and Hotel

Marble Hill

Miranda

P6,605

P7,189 total

includes taxes & fees

Oct 13 - Oct 14

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A room with wooden paneling, a ceiling fan, a dining table with chairs, and a sofa.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

A two-story house with a deck and a covered porch.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

Anonymous traveler

P7,539

P18,651 total

includes taxes & fees

Oct 21 - Oct 22

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Hotels recommended for families in Puxico

Hampton Inn By Hilton Dexter

Dexter

P6,130

P6,945 total

includes taxes & fees

Oct 25 - Oct 26

Dexter Inn

Dexter

P4,335

P4,911 total

includes taxes & fees

Oct 13 - Oct 14

Drury Inn & Suites Poplar Bluff

Poplar Bluff

P5,905

P6,671 total

includes taxes & fees

Oct 29 - Oct 30

Hampton Inn Poplar Bluff

Poplar Bluff

P5,714

P6,398 total

includes taxes & fees

Oct 18 - Oct 19

Travelodge by Wyndham Dexter

Dexter

P5,428

P6,150 total

includes taxes & fees

Nov 1 - Nov 2

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

P6,087

P6,877 total

includes taxes & fees

Oct 18 - Oct 19

Motel 6 Poplar Bluff, MO

Poplar Bluff

P4,467

P5,001 total

includes taxes & fees

Oct 26 - Oct 27

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

P5,277

P5,962 total

includes taxes & fees

Oct 18 - Oct 19

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Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

10/10 Excellent

"Hotel has been recently remodeled. Room was very clean. Staff was so helpful especially Sue who checked us in!"

EC Reed's Mercantile and Hotel

10/10 Excellent

"On street parking, quiet little town, absolutely beautiful little hotel, diner, and general store. Very unique! It’s a whole experience staying here. I would love an opportunity to stop here again if I’m ever going through this area again."