Penrose Hotels near St. Louis

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Our top choices for Penrose hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 7.3 km from Penrose
8.4 out of 10, Very Good, (4017)
"Everything was great!"
United States
Kathryn
The price is P4,971
P5,862 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 6.7 km from Penrose
8.8 out of 10, Excellent, (1154)
"Really nice hotel!"
United States
DARIN
The price is P5,130
P6,101 total
includes taxes & fees
Dec 21 - Dec 22
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 7.3 km from Penrose
9.4 out of 10, Exceptional, (3285)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is P7,932
P9,275 total
includes taxes & fees
Dec 23 - Dec 24
Drury Plaza Hotel St. Louis at the Arch

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
26.7 km from Penrose
7.4 out of 10, Good, (1004)
"Bed was comfortable, room was quiet, breakfast had limited options and bathroom was tiny. Overall great value for the price! "
United States
Alison
The price is P2,705
P3,111 total
includes taxes & fees
Dec 21 - Dec 22
Quality Inn O'Fallon IL - St. Louis

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 6.3 km from Penrose
7.6 out of 10, Good, (591)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is P4,795
P5,607 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru By Hilton St. Louis Downtown

The Principal Hotel

The Principal Hotel
3.5 star property
26.5 km from Penrose
9.8 out of 10, Exceptional, (191)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is P6,629
P7,357 total
includes taxes & fees
Dec 18 - Dec 19
The Principal Hotel

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
30.5 km from Penrose
8.0 out of 10, Very Good, (1010)
"Great staff, clean room. "
United States
Amanda
The price is P5,280
P6,068 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn St. Charles St. Peters

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 6.7 km from Penrose
8.8 out of 10, Excellent, (1244)
"Great hospitality"
United States
Alejandro
The price is P6,457
P7,679 total
includes taxes & fees
Dec 23 - Dec 24
Embassy Suites by Hilton St. Louis Downtown

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.1 km from Penrose
8.8 out of 10, Excellent, (3034)
"Clean room, good breakfast and good location "
United States
Martin
The price is P5,312
P6,201 total
includes taxes & fees
Dec 21 - Dec 22
Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
13.3 km from Penrose
9.4 out of 10, Exceptional, (2745)
"Friendly staff.. airport shuttle service excellent!!"
United States
Nancy and Ron
The price is P5,288
P6,225 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Pear Tree Inn St. Louis Airport

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
16.6 km from Penrose
9.0 out of 10, Wonderful, (1449)
"Awesome place to stay!!"
United States
Kaitlyn
The price is P5,198
P6,908 total
includes taxes & fees
Dec 23 - Dec 24
River City Casino & Hotel

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 7.1 km from Penrose
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is P6,064
P7,151 total
includes taxes & fees
Dec 24 - Dec 25
Hilton Pennywell St. Louis at the Arch

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
16.7 km from Penrose
8.4 out of 10, Very Good, (1618)
"great stay."
United States
Allison
The price is P3,361
P4,108 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Motel 6 Hazelwood, MO

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
28.9 km from Penrose
9.4 out of 10, Exceptional, (703)
"Great breakfast ! "
United States
Jeanette
The price is P5,494
P6,097 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express Troy by IHG

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
21.1 km from Penrose
7.4 out of 10, Good, (1003)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is P3,785
P4,390 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 6.6 km from Penrose
9.0 out of 10, Wonderful, (1010)
"Was a great stay. "
United States
Lorilyn
The price is P5,944
P7,069 total
includes taxes & fees
Dec 24 - Dec 25
Courtyard by Marriott St. Louis Downtown/Convention Center

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 7 km from Penrose
8.6 out of 10, Excellent, (1174)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
The price is P5,734
P6,705 total
includes taxes & fees
Dec 23 - Dec 24
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
12 km from Penrose
9.2 out of 10, Wonderful, (1002)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
Best Western Plus St. Louis Airport Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
5.8 km from Penrose
9.0 out of 10, Wonderful, (1917)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is P6,971
P8,290 total
includes taxes & fees
Dec 28 - Dec 29
Moonrise Hotel

Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
18.3 km from Penrose
8.0 out of 10, Very Good, (1033)
"The room was great and the bed was very comfortable "
United States
Joyce
The price is P4,945
P5,735 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Best Western Plus St. Louis West-Westport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Penrose

Find the best Penrose areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Penrose Hotel Reviews

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Frequently asked questions

What's it like in Penrose?
Travelers are sure to enjoy a stay in St. Louis's Penrose neighborhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.
If I need to cancel my hotel reservation in Penrose, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the top deals on offer in Penrose.
What is there to do around this St. Louis neighborhood?
Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.