Hotels near Penn Center

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Our top choices for Penn Center hotels

City Loft Hotel

City Loft Hotel
3.5 star property
9.9 km from Penn Center
9.4 out of 10, Exceptional, (759)
"Great place to stay in city center Beaufort. Easy free parking, friendly staff, comfy mattresses, nice bathroom and shower. Location was perfect for walking to shops and restaurants."
United States
Laura
The price is P8,383
P9,222 total
includes taxes & fees
Dec 28 - Dec 29
City Loft Hotel

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
10.2 km from Penn Center
9.4 out of 10, Exceptional, (1000)
"Perfect spot!"
United States
Tricia
The price is P8,739
P9,613 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Sea Island Inn

Beaufort Inn

Beaufort Inn
3.5 star property
10 km from Penn Center
9.0 out of 10, Wonderful, (1000)
"The staff were friendly and the cottage room was clean and comfortable. "
United States
Samantha
Beaufort Inn

The Emerald Boutique Stays

The Emerald Boutique Stays
2.5 star property
10 km from Penn Center
9.2 out of 10, Wonderful, (221)
"Close to downtown shopping and restaurants. Nice room and helpful staff."
United States
Jeffrey
The price is P7,576
P8,334 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Emerald Boutique Stays

607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort
2.5 star property
9.8 km from Penn Center
9.6 out of 10, Exceptional, (90)
"Great Inn! Location, view, cleanliness, friendly staff!"
United States
Nicole
607 Bay Inn Downtown Beaufort

Circa 1785

Circa 1785
4.0 star property
10.3 km from Penn Center
9.6 out of 10, Exceptional, (137)
"Our room (#4) was FABULOUS. Huge with great bathroom and comfy bed and linens. Did not want to leave. 😫"
United States
Jill
The price is P7,559
P8,315 total
includes taxes & fees
Dec 28 - Dec 29
Circa 1785

Rhett House Inn

Rhett House Inn
4.0 star property
10.3 km from Penn Center
9.2 out of 10, Wonderful, (643)
"What a lovely stay. Beautiful, clean and friendly staff made this stay wonderful. Will stay again while in Beaufort."
United States
REBECCA
The price is P8,557
P11,295 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Rhett House Inn

Anchorage 1770

Anchorage 1770
5.0 star property
10.3 km from Penn Center
9.2 out of 10, Wonderful, (219)
"Great property at a wonderful location."
United States
Dave
Anchorage 1770

Cuthbert House

Cuthbert House
4.5 star property
10.4 km from Penn Center
9.2 out of 10, Wonderful, (951)
"Excellent accommodations. Staff was very friendly & helpful. Will definitely come back. The Inn is beautiful. "
United States
Melanie
The price is P22,121
P24,334 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Cuthbert House

Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort
2.0 star property
10.2 km from Penn Center
6.0 out of 10, (907)
"The room could have been a little cleaner but all and all it was Great! "
United States
Gina
The price is P3,502
P3,852 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Super 8 by Wyndham Port Royal/Beaufort

Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort
3.0 star property
12 km from Penn Center
8.4 out of 10, Very Good, (1000)
"Good hotel"
United States
joshua
The price is P5,002
P5,502 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hilton Garden Inn Beaufort

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
3.0 star property
12.7 km from Penn Center
8.2 out of 10, Very Good, (1002)
"Beautiful hotel, love the breakfast, wonderful staff"
United States
Jaye
The price is P5,227
P5,750 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Hampton Inn Beaufort

Hampton Inn Beaufort
2.5 star property
13 km from Penn Center
8.4 out of 10, Very Good, (1000)
"Room was spotless and staff very courtesy."
United States
Griselda
The price is P5,591
P6,150 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hampton Inn Beaufort

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
14.9 km from Penn Center
9.0 out of 10, Wonderful, (712)
"Awesome stay!!!"
United States
Michael
The price is P5,501
P6,051 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Tru by Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC
3.0 star property
15 km from Penn Center
9.2 out of 10, Wonderful, (722)
"Room was spotless and beds comfortable"
United States
Judy
The price is P6,570
P7,227 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Home2 Suites BY Hilton Beaufort, SC

Newly Updated Poolside Studio Steps From Beach, Sandbar, & Tennis

Newly Updated Poolside Studio Steps From Beach, Sandbar, & Tennis
2.5 star property
11 km from Penn Center
8.8 out of 10, Excellent, (3)
"Great stay with the family, great location"
United States
Troy
The price is P8,450
P18,819 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Newly Updated Poolside Studio Steps From Beach, Sandbar, & Tennis

Howard Johnson by Wyndham Beaufort/Parris Island

Howard Johnson by Wyndham Beaufort/Parris Island
2.0 star property
15.1 km from Penn Center
6.0 out of 10, (896)
"Room was good "
United States
INDIRA
The price is P4,631
P5,094 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Howard Johnson by Wyndham Beaufort/Parris Island

Oasis Inn

Oasis Inn
2.5 star property
12.8 km from Penn Center
7.4 out of 10, Good, (596)
"Fantastic stay. The staff was very friendly and helpful and the rooms were what I needed. Thank you "
United States
Chris
The price is P5,296
P5,825 total
includes taxes & fees
Dec 26 - Dec 27
Oasis Inn

Country Inn & Suites by Radisson, Beaufort West, SC

Country Inn & Suites by Radisson, Beaufort West, SC
2.5 star property
13.4 km from Penn Center
7.2 out of 10, Good, (1003)
"I enjoyed everything. Parking, breakfast, staff, and parking was good. "
United States
Deaven
The price is P5,434
P5,977 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Country Inn & Suites by Radisson, Beaufort West, SC

Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS
2.5 star property
13.7 km from Penn Center
7.4 out of 10, Good, (1000)
"Overall i would stay here again."
United States
Joshua
The price is P4,942
P5,437 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Sleep Inn Beaufort near MCAS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Penn Center Hotel Reviews

Hotels near other Penn Center attractions

Frequently asked questions

What's the area like around Penn Center?
Penn Center is located in a historic area of Saint Helena Island known for its beautiful island views. You'll find 63 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Penn Center?
Beaufort Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and private balconies. You'll find it 6.2 mi (10 km) from Penn Center. Other good choices around the area include Best Western Sea Island Inn and Rhett House Inn.
How many hotels should I expect to find close to Penn Center?
Expedia has 63 hotels and other accommodations a few miles from Penn Center.
If I need to cancel the hotel reservation for my stay near Penn Center, will I receive a refund?
Yes, most hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the top deals on offer near Penn Center.
What can I see and do near Penn Center?
Attractions like York W. Bailey Museum and Red Piano Too Gallery highlight the local culture. You can enjoy nature at Horse Island, Cherry Hill Knoll Island, or Sheep Island. You might plan a visit to Cat Island Driving Range or Sanctuary Golf Club while you're in the area.