A pier extending into calm waters with a small boat docked at the end.

Panacea Hotels

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Check prices for these dates

Tonight
Aug 20 - Aug 21
Tomorrow
Aug 21 - Aug 22
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

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Our top choices for Panacea hotels

Reserve now, pay later
Hotel
Pet friendly
Breakfast included
Public Beach Access

1. The Panacea Motel

The Panacea Motel
Panacea
United States
Michelle
P7,361
P8,208 total
includes taxes & fees
Aug 23 - Aug 24
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
United States
Lydia
P6,377
P7,110 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
Crawfordville
United States
Megan
P7,206
P8,282 total
includes taxes & fees
Sep 8 - Sep 9
Wildwood Inn

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
United States
Sherry
P6,985
P7,789 total
includes taxes & fees
Aug 23 - Aug 24
The Lodge at Wakulla Springs

5. Franklin Inn

Franklin Inn
Carrabelle
United States
Melynda
P5,285
P5,840 total
includes taxes & fees
Aug 23 - Aug 24
Franklin Inn

6. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
United States
Mike
P8,355
P11,583 total
includes taxes & fees
Aug 21 - Aug 22
St James Bay Golf & Pickleball Resort

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
United States
David
P6,510
P7,193 total
includes taxes & fees
Sep 1 - Sep 2
The Old Carrabelle Hotel

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
United States
Tina
P11,158
P12,329 total
includes taxes & fees
Aug 24 - Aug 25
The Moorings Hotel and Marina
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Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
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Bald Point State Park

8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
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Mashes Sand Beach

8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
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Wilson Beach

Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
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Panacea Springs

Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
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Public Beach Access

Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
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Gulf Specimen Public Aquarum

Take the kids to visit the sea life you'll find at Gulf Specimen Public Aquarum during your trip to Panacea. Stroll along the beaches in this relaxing area, or seek out the fishing spots.
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Panacea Park

After visiting Panacea Park, make a plan to see the other sights and activities in Panacea. Stroll along this relaxing area's beaches, or simply enjoy its seafood restaurants.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Top Panacea Hotel Reviews

The Panacea Motel

The Panacea Motel

10/10 Excellent
"I loved the retro feel of the place."
Michelle 1-night trip
Posted 7 days ago
The Panacea Motel

More cheap stays in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
P5,285
P5,840 total
Aug 23 - Aug 24
includes taxes & fees
7.8/10 Good! (504 reviews)
Franklin Inn
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL
P6,377
P7,110 total
Sep 6 - Sep 7
includes taxes & fees
Best Western Wakulla Inn & Suites
The Old Carrabelle Hotel

The Old Carrabelle Hotel

201 Tallahassee St Carrabelle FL
P6,510
P7,193 total
Sep 1 - Sep 2
includes taxes & fees
9.6/10 Exceptional! (43 reviews)
The Old Carrabelle Hotel
The Panacea Motel

The Panacea Motel

1545 Coastal Hwy Panacea FL
P7,361
P8,208 total
Aug 23 - Aug 24
includes taxes & fees
9/10 Wonderful! (188 reviews)
The Panacea Motel
The Moorings Hotel and Marina

The Moorings Hotel and Marina

1000 Hwy 98 Carrabelle FL
P11,158
P12,329 total
Aug 24 - Aug 25
includes taxes & fees
The Moorings Hotel and Marina
Cozy Waterfront 'island House' on Live Oak Island!

Cozy Waterfront 'island House' on Live Oak Island!

Crawfordville FL
Get ratesCozy Waterfront 'island House' on Live Oak Island!

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 231 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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