A pier extending into calm waters with a small boat docked at the end.

Panacea Hotels

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Our top choices for Panacea hotels

1. The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (186 reviews)
"Great stay! Would definitely stay again!!"
United States
Jacob
The price is P7,260
P8,094 total
includes taxes & fees
Aug 10 - Aug 11
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (1,004 reviews)
"Great stay! Nice property. Nice rooms. Friendly staff. "
United States
Lydia
The price is P8,190
P9,131 total
includes taxes & fees
Sep 2 - Sep 3
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,002 reviews)
"The hotel and room we nice and clean, but above all the staff was super kind and friendly!"
United States
Megan
The price is P7,788
P8,928 total
includes taxes & fees
Sep 1 - Sep 2
Wildwood Inn

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice place to stay. The hotel is beautiful, it looks like you went back in time when you arrive. Room is spacious and has a nice shower."
United States
Judith
The price is P6,917
P7,712 total
includes taxes & fees
Aug 12 - Aug 13
The Lodge at Wakulla Springs

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (411 reviews)
"Most certainly coming back!"
United States
Mike
The price is P9,728
P13,141 total
includes taxes & fees
Aug 7 - Aug 8
St James Bay Golf & Pickleball Resort

6. Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (501 reviews)
"We got in late and the keys were ready for us….for one night the accommodations were good! Very close to a beautiful beach near the hotel that we absolutely loved! Dolphins and calm bay waves. This was perfect for our trip! Thank you!"
United States
Melynda
The price is P5,754
P6,358 total
includes taxes & fees
Aug 9 - Aug 10
Franklin Inn

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.6 out of 10, Exceptional, (41 reviews)
"We enjoyed this lovely historic property! The bed and linens were comfortable. It was interesting greeting the other guest as we saw each other coming and going. There are no TVs on the property so that took some adjustment for an avid television watcher. We enjoyed learning about the small community and had some good meals at the small local restaurants. We really enjoyed our stay!"
United States
Gilbert
The price is P6,443
P7,119 total
includes taxes & fees
Aug 9 - Aug 10
The Old Carrabelle Hotel

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very Good, (51 reviews)
"Very clean room!"
United States
Heriberto
The price is P11,043
P12,203 total
includes taxes & fees
Aug 6 - Aug 7
The Moorings Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Top Panacea Hotel Reviews

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Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 231 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Gulf Specimen Public Aquarum. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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