A calm lake with a wooden pier extending into the water, surrounded by tall grasses.

Panacea Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Panacea hotels

A pink door with a window, set in a corrugated metal exterior with wooden trim.

1. The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (200 reviews)
"Other than everything close perfect spot"
United States
Dashawn
The price is P7,563
P8,432 total
includes taxes & fees
Nov 8 - Nov 9
The Panacea Motel
A wooden boardwalk leading to a beach with green vegetation and a clear sky.

2. Breezy Home w/ Grills, Pool & Beach Access!

Breezy Home w/ Grills, Pool & Beach Access!
3.0 star property
Panacea
The price is P17,346
P36,344 total
includes taxes & fees
Nov 24 - Nov 25
Breezy Home w/ Grills, Pool & Beach Access!
A spacious indoor area with tiled flooring, multiple tables and chairs, a stone fireplace, and a glass door entrance.

3. Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,002 reviews)
"beautiful hotel"
United States
Donna
The price is P7,457
P8,569 total
includes taxes & fees
Nov 30 - Dec 1
Wildwood Inn
A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.

4. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (1,000 reviews)
"Great Stay and amazing staff!"
United States
Alexus
The price is P6,862
P7,651 total
includes taxes & fees
Nov 19 - Nov 20
Best Western Wakulla Inn & Suites
A spacious lobby with leather sofas, a coffee table, and a large window with arched frames.

5. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.6 out of 10, Exceptional, (1,002 reviews)
"Great stay!"
United States
Joy
The price is P6,798
P7,580 total
includes taxes & fees
Nov 9 - Nov 10
The Lodge at Wakulla Springs
A kitchen with white cabinets, a microwave, a coffee maker, and a dishwasher.

6. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (433 reviews)
"Very nice resort."
United States
Eboni
The price is P6,061
P9,002 total
includes taxes & fees
Nov 6 - Nov 7
St James Bay Golf & Pickleball Resort
A marina with boats docked, a small building, and a clear sky.

7. The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very good, (55 reviews)
"Nice area, close to lots of places. Nice being on the water. Seagulls were fun to watch. Staff was great and attentive."
United States
Tina
The price is P8,760
P9,680 total
includes taxes & fees
Nov 9 - Nov 10
The Moorings Hotel and Marina
A covered patio with a table and chairs, a wooden ceiling fan, and a view of the surrounding greenery.

8. The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.6 out of 10, Exceptional, (55 reviews)
"It’s a very nice place, very nice owner. Very accommodating."
United States
Jeffrey
The price is P6,347
P7,014 total
includes taxes & fees
Nov 19 - Nov 20
The Old Carrabelle Hotel
A hotel room with two beds, a nightstand, a lamp, and a bathroom visible through an open door.

9. Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (513 reviews)
"Was a good place for a cost effective one night stay."
United States
Nathan
The price is P5,427
P5,997 total
includes taxes & fees
Nov 15 - Nov 16
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
See properties

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

See all hotels in Panacea
A coastal resort with beachfront villas and a clear blue sky.

Top Panacea Hotel Reviews

More cheap stays in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
The price is P5,427 per night from Nov 15 to Nov 16
P5,427
P5,997 total
Nov 15 - Nov 16
includes taxes & fees

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 228 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

Explore a world of travel with Expedia