Panacea Hotels

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Our top choices for Panacea hotels

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (139)
"A v nice place to stay "
United States
Harry
The Panacea Motel

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
10.0 out of 10, Exceptional, (1)
The price is P7,986
P8,825 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Old Carrabelle Hotel

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1000)
"Great stay. Boat tour was enjoyable. Quiet relaxing place"
United States
PATRICIA
The Lodge at Wakulla Springs

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (370)
"Very clean update villas"
United States
Jack
The price is P8,280
P9,149 total
includes taxes & fees
Jan 1 - Jan 2, 2026
St James Bay Golf & Pickleball Resort

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (946)
"Great hotel. Very good customer service and very clean"
United States
claudina
The price is P6,530
P7,281 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Wakulla Inn & Suites

Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (456)
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is P5,020
P5,547 total
includes taxes & fees
Dec 22 - Dec 23
Franklin Inn

The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very Good, (39)
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is P8,104
P8,955 total
includes taxes & fees
Dec 22 - Dec 23
The Moorings Hotel and Marina

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1001)
"Enjoyed our stay and would definitely stay again!"
United States
Corey
The price is P6,742
P7,752 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Wildwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

More cheap stays in Panacea

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 213 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Alligator Harbor Aquatic Preserve. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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