Hotels near Palmdale Regional Medical Center

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Our top choices for Palmdale Regional Medical Center hotels

Outdoor pool
DoubleTree by Hilton Palmdale, CA

DoubleTree by Hilton Palmdale, CA

DoubleTree by Hilton Palmdale, CA
4.0 star property
1.1 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (779)
"The hotel was very nice. So clean and the staff was welcoming. "
United States
Crystal
The price is P5,013
P5,625 total
includes taxes & fees
Jan 9 - Jan 10, 2026
DoubleTree by Hilton Palmdale, CA
Lobby
Element Palmdale

Element Palmdale

Element Palmdale
3.0 star property
1.5 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (634)
"Stay was amazing! Our room was amazing and the staff was so friendly!"
United States
Caitlin
The price is P5,600
P6,283 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Element Palmdale
View from property
Fairfield Inn & Suites by Marriott Palmdale West

Fairfield Inn & Suites by Marriott Palmdale West

Fairfield Inn & Suites by Marriott Palmdale West
2.5 star property
3 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (498)
"The hotel was very nice and clean I appreciate it the friendly staff. "
United States
Alejandro
The price is P5,952
P6,678 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Fairfield Inn & Suites by Marriott Palmdale West
Sports facility
Home2 Suites by Hilton Palmdale, CA

Home2 Suites by Hilton Palmdale, CA

Home2 Suites by Hilton Palmdale, CA
3.0 star property
0.8 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (391)
"The breakfast was great!"
United States
Wendy
The price is P4,711
P5,285 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Home2 Suites by Hilton Palmdale, CA
Reception
Embassy Suites Palmdale

Embassy Suites Palmdale

Embassy Suites Palmdale
3.5 star property
1.6 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (1116)
"Great location"
United States
Juan
The price is P7,793
P8,743 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Embassy Suites Palmdale
Property amenity
Residence Inn Palmdale Lancaster

Residence Inn Palmdale Lancaster

Residence Inn Palmdale Lancaster
3.0 star property
2.3 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (388)
"Everything was good. Staff was very nice. "
United States
Niquisha
The price is P7,097
P7,949 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Residence Inn Palmdale Lancaster
Interior
Holiday Inn Palmdale-Lancaster by IHG

Holiday Inn Palmdale-Lancaster by IHG

Holiday Inn Palmdale-Lancaster by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1012)
"Nice place to stay at !!"
United States
GAUDENCIO
The price is P5,471
P6,138 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Palmdale-Lancaster by IHG
Property amenity
Courtyard Palmdale

Courtyard Palmdale

Courtyard Palmdale
3.0 star property
2.3 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (937)
"The hotel was very clean and the staff was courteous. "
United States
Kenley
The price is P5,941
P6,654 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Courtyard Palmdale
Restaurant
Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale
3.0 star property
2.3 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1000)
"Room was clean, staff was great!!"
United States
Cecilia
The price is P6,073
P6,802 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hilton Garden Inn Palmdale
Free continental breakfast
Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites
2.5 star property
0.5 km from Palmdale Regional Medical Center
8.6 out of 10, Excellent, (1002)
"Always a great place to stay. "
United States
Julio
The price is P5,242
P5,871 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Best Western Plus John Jay Inn & Suites
Exterior
Staybridge Suites Palmdale by IHG

Staybridge Suites Palmdale by IHG

Staybridge Suites Palmdale by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.4 out of 10, Very Good, (588)
"The staff is very friendly the room was cozy and the breakfast was delicious "
United States
Julio
The price is P6,118
P6,864 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Staybridge Suites Palmdale by IHG
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Hampton Inn & Suites Palmdale

Hampton Inn & Suites Palmdale

Hampton Inn & Suites Palmdale
2.5 star property
2 km from Palmdale Regional Medical Center
8.4 out of 10, Very Good, (1000)
"Clean room and courteous staff. Complimentary breakfast is always delicious. "
United States
Tamera
The price is P4,484
P5,142 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn & Suites Palmdale
Laptop workspace, blackout drapes, bed sheets
Woodspring Suites Palmdale - Lancaster

Woodspring Suites Palmdale - Lancaster

Woodspring Suites Palmdale - Lancaster
2.5 star property
3 km from Palmdale Regional Medical Center
8.4 out of 10, Very Good, (181)
"This is one of the best places to stay away from home."
United States
Terenia
The price is P4,355
P4,886 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Woodspring Suites Palmdale - Lancaster
Outdoor pool
Palms Inn & Suites

Palms Inn & Suites

Palms Inn & Suites
2.5 star property
0.8 km from Palmdale Regional Medical Center
6.8 out of 10, (1140)
"I really enjoyed my stay."
United States
Anna
Palms Inn & Suites
Lobby
Red Roof Inn Palmdale - Lancaster

Red Roof Inn Palmdale - Lancaster

Red Roof Inn Palmdale - Lancaster
2.0 star property
1.4 km from Palmdale Regional Medical Center
5.0 out of 10, (1005)
"Very nice at check in"
United States
Christina
The price is P3,882
P4,348 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Red Roof Inn Palmdale - Lancaster
Microwave
Motel 6 Palmdale, CA

Motel 6 Palmdale, CA

Motel 6 Palmdale, CA
2.0 star property
0.9 km from Palmdale Regional Medical Center
7.0 out of 10, Good, (400)
"A good place to stay."
United States
Edith
The price is P9,768
P10,949 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Motel 6 Palmdale, CA
Property amenity
Fairfield Inn & Suites by Marriott Lancaster Palmdale

Fairfield Inn & Suites by Marriott Lancaster Palmdale

Fairfield Inn & Suites by Marriott Lancaster Palmdale
2.5 star property
11.1 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (676)
"Have stayed here for the 2nd time and it has been great! "
United States
Maria
The price is P6,297
P6,970 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Fairfield Inn & Suites by Marriott Lancaster Palmdale
Property amenity
Residence Inn by Marriott Lancaster Palmdale

Residence Inn by Marriott Lancaster Palmdale

Residence Inn by Marriott Lancaster Palmdale
3.0 star property
12.8 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (282)
"Clean room, great staff! "
United States
Janet
The price is P8,454
P9,375 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Residence Inn by Marriott Lancaster Palmdale
Terrace/patio
TownePlace Suites by Marriott Lancaster, CA

TownePlace Suites by Marriott Lancaster, CA

TownePlace Suites by Marriott Lancaster, CA
3.0 star property
11.3 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (356)
"I absolutely love seeing at this place. It is so convenient clean and the staff is absolutely amazing and helpful."
United States
Sandra
The price is P7,453
P8,250 total
includes taxes & fees
Jan 8 - Jan 9, 2026
TownePlace Suites by Marriott Lancaster, CA
Balcony view
Oxnard Inn Lancaster

Oxnard Inn Lancaster

Oxnard Inn Lancaster
3.0 star property
10.4 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1000)
"Great customer service and delicious breakfast. "
United States
Noe
The price is P5,598
P6,186 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Oxnard Inn Lancaster
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Palmdale Regional Medical Center Hotel Reviews

Santa Clarita Motel

Santa Clarita Motel

10/10 Excellent
"All good - parking, quoet,large,clean."
Barbara 1-night trip
Posted 2 days ago
Santa Clarita Motel

Hotels near other Palmdale Regional Medical Center attractions

I <3 this place! I hope I can find w place like this back in WA!
Photo by Christine Buggs
Open Photo by Christine Buggs

Antelope Valley Mall

4.1/5 (133 reviews)
You can search for that perfect souvenir at Antelope Valley Mall during your trip to Palmdale. Check out the shops and top-notch restaurants in this family-friendly area.
See properties
Panoramic image looking east of Palmdale in Los Angeles county showing the California aqueduct in the foreground.

Lake Palmdale

4.1/5 (36 reviews)
Commune with nature and explore the great outdoors at Lake Palmdale during your travels in Palmdale. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Frequently asked questions

What's the area like around Palmdale Regional Medical Center?
Palmdale Regional Medical Center is located in a welcoming area of Palmdale known for its array of dining options. If you're looking for a convenient place to stay, check out the 29 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Palmdale Regional Medical Center?
DoubleTree by Hilton Palmdale, CA is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.7 mi (1.1 km) from Palmdale Regional Medical Center. Another good choice is Embassy Suites Palmdale, located 1 mi (1.6 km) away.
How many hotels will I find close to Palmdale Regional Medical Center?
Expedia has 29 hotels and other accommodations within a mile from Palmdale Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Palmdale Regional Medical Center, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Palmdale Regional Medical Center.
What can I see and do near Palmdale Regional Medical Center?
You can enjoy live performances at Palmdale Playhouse and Palmdale Amphitheater. If you have some time to wander around the area, you might stop by Antelope Valley Country Club, Rancho Vista Golf Club, or Cinemark Antelope Valley Mall. If you want to see more of the surrounding area, you can plan a visit to Antelope Valley Mall and Palmdale City Hall.

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