Opelousas Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 16 - Jan 18
In two months
Feb 27 - Mar 1
In three months
Mar 27 - Mar 29
In four months
Apr 24 - Apr 26

Our top choices for Opelousas vacation rentals

Individually decorated, individually furnished, laptop workspace
Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
4.0 star property
Rayne
9.6 out of 10, Exceptional, (94)
"Tons of charm, quiet, secluded AND close to main roads, great views, great meals and the property managers were very friendly and happy. This was a great experience and I hope to go back in the future."
United States
Darren
The price is P8,753
P9,913 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Maison D'Memoire Bed & Breakfast Cottages
Exterior
Evangeline A in Lafayette

Evangeline A in Lafayette

Evangeline A in Lafayette
2.0 star property
McComb-Veazey
10.0 out of 10, Exceptional, (1)
"Such a cute little gem, right outside of downtown Lafayette. The house was lovely inside and out. The recent renovations and layout of the house makes it feel so much bigger than it is. The vaulted ceilings, and beautiful attention to details in the interior design made this a new place to stay when we visit! "
United States
William
The price is P5,324
P8,224 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Evangeline A in Lafayette
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Opelousas Hotel Reviews

Microtel Inn & Suites by Wyndham Scott/Lafayette

Microtel Inn & Suites by Wyndham Scott/Lafayette

10/10 Excellent
"Room was very clean n staff were very helpful"
Cheval 1-night trip
Posted 6 days ago
Microtel Inn & Suites by Wyndham Scott/Lafayette

Find out more about Opelousas

Search for holiday rentals in Opelousas on Expedia! You can easily find your home rentals, villas, holiday apartments in Opelousas using one of the methods below:

  • View our selection of featured holiday rentals in Opelousas
  • Use the map to find apartments and other holiday homes in the Opelousas neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Opelousas while they last

Look no further and take a look at our great range of rental properties in Opelousas!

Frequently asked questions

Can I find vacation rentals in Opelousas?

Yes, we give you a choice of vacation rentals in Opelousas close to Louisiana Orphan Train Museum, or you can select a more remote option if you're looking for extra privacy while you relax. Opelousas is known for its casinos and cafes. Make sure you have time to check out the art and churches during your trip.

How many vacation rentals are there in Opelousas?

Choose from 3 Expedia vacation rentals in Opelousas for a memorable vacation.

What’s there to see and do in Opelousas?

Cultural attractions include Louisiana Orphan Train Museum and Fireman's Museum, whereas South Park is one spot to enjoy nature. Evangeline Downs Racetrack & Casino and Opelousas Historic District are other places to visit while you're in town.

What are vacation rentals like in Opelousas?

Vacation rentals are privately owned accommodations you can reserve for several days or more in Opelousas. Vacation rentals feature amenities such as kitchens and laundry facilities to help you enjoy your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for a small group gathering.