Fashion is at the core of this neighborhood south of Times Square, where bustling streets and soaring buildings reflect the big city’s go-getter spirit.

The Garment District is a center for global fashion, where countless hopefuls have toiled to establish themselves in the business of creativity. At first glance, the 20 blocks that make up the district, from Sixth Avenue and 34th Street to Ninth Avenue and 42nd Street, appear to be lined with unremarkable buildings. Look more closely to see hints of the high-octane industry housed here, from designers’ studios to fabric stores and showrooms.

Ask at the Fashion Center Information Kiosk for a free map of the Garment District. Set out down Seventh, also known as Fashion Avenue. Look for the 28 brass plaques of the Fashion Walk of Fame, which highlights influential American designers throughout the ages. Plan ahead and hire a licensed tour guide to walk you through a century of fashion.

Explore the Museum at the Fashion Institute of Technology to delve into the area’s history, as well as other fashion-related topics of interest. As you wander, appreciate the bright murals and public sculptures dotted throughout the Garment District Plazas. Art fans will also enjoy a quick stop at Space for Public Art, a venue for small, free exhibits.

Visitors to the Garment District often have one thing in mind: shopping. Many of the area’s showrooms and wholesale warehouses are open only by appointment. A guided tour can help with access and wayfinding. Urban Oasis offers tours that prioritize shopping, as well as educational tours tracing how garments are designed and produced.

You don’t need a guide to indulge, however. Channel your inner designer while feeling velvet, suede and silk at the iconic Mood Fabrics or head to Macy’s Herald Square for a classic department store experience.

If you begin to tire, pick up a snack from a street vendor and take advantage of the public seating in the plaza at Herald Square, where street musicians often play delightful melodies.