A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Mytilene Vacation Rentals

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Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Mytilene vacation rentals

In-room safe, desk, WiFi (free)

1. Akti Vigla Premium

Akti Vigla Premium
Lesvos
10.0 out of 10, Exceptional, (19 reviews)
"Very clean room, excellent easy check in. Easy to find and free parking. Perfect location close to the airport. Ocean view."
United States
Gertrud
The price is P4,060
P4,591 total
includes taxes & fees
Oct 18 - Oct 19
Akti Vigla Premium
Garden

2. Loriet Hotel

Loriet Hotel
4.0 star property
Lesvos
8.4 out of 10, Very good, (91 reviews)
"Lovely mansion house and a great breakfast."
United States
Malcolm
The price is P6,595
P7,946 total
includes taxes & fees
Oct 1 - Oct 2
Loriet Hotel
Exterior

3. Elies Residences

Elies Residences
Lesvos
9.8 out of 10, Exceptional, (36 reviews)
"Beautiful quiet nice little place.Very cosy !!"
Australia
Anonymous traveler
The price is P8,885
P9,877 total
includes taxes & fees
Oct 1 - Oct 2
Elies Residences
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mytilene Hotel Reviews

Akti Vigla Premium

Akti Vigla Premium

10/10 Excellent
"Breakfast was fantastic and we loved the engineering of the patio doors. They tilt and open"
Rebecca 1-night trip
Posted 7 days ago
Akti Vigla Premium

Find out more about Mytilene

Search for holiday rentals in Mytilene on Expedia! You can easily find your home rentals, villas, holiday apartments in Mytilene using one of the methods below:

  • View our selection of featured holiday rentals in Mytilene
  • Use the map to find apartments and other holiday homes in the Mytilene neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Mytilene while they last

Look no further and take a look at our great range of rental properties in Mytilene!

Frequently asked questions

Are there vacation rentals in Mytilene?

Yes, we give you a choice of vacation rentals close to the most popular attractions in Mytilene, or you can select a more remote option if you want a relaxing place to stay. Nature enthusiasts will enjoy the seaside in Mytilene. Make sure you have time to check out the museums and monuments during your trip.

How many vacation rentals will I find in Mytilene?

Choose from 15 Expedia vacation rentals in Mytilene for a memorable vacation.

What’s there to see and do in Mytilene?

Enjoy the outdoors at Thermes Gera Hot Springs and Thermi Beach, or simply take in cultural attractions like Ecclesiastical Byzantine Museum and Theriade Library and Museum of Modern Art. While here, Port of Mytilene and Mytilini Castle are other places worth a visit.

What’s a vacation rental in Mytilene like?

A vacation rental is a private property you can stay in for a couple of days or more in Mytilene. Vacation rentals provide amenities such as kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of seclusion away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive choice for family trips.