Weather will likely play an important role when you plan your trip to Murrells Inlet, and keep in mind that cheaper options are usually available when the weather isn't as good. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 53°F. The rainiest months in Murrells Inlet are August, July, September, and June, with each month seeing an average of 8 inches of rainfall.