Photo by Southernmost Illinois Tourism Bureau
Murphysboro Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in Murphysboro
Family friendly
Check prices for these dates
Top 10 trending Murphysboro hotels

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
9.4 out of 10, Exceptional, (466)
The price is P5,936
P6,588 total
includes taxes & fees
Sep 7 - Sep 8

Super 8 by Wyndham Carbondale
Super 8 by Wyndham Carbondale
7.2 out of 10, Good, (1004)
The price is P3,710
P4,266 total
includes taxes & fees
Aug 18 - Aug 19

Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHG
8.8 out of 10, Excellent, (594)
The price is P5,536
P6,366 total
includes taxes & fees
Aug 24 - Aug 25

Home2 Suites by Hilton Carbondale
Home2 Suites by Hilton Carbondale
8.8 out of 10, Excellent, (479)
The price is P8,199
P9,427 total
includes taxes & fees
Aug 24 - Aug 25

Drury Inn & Suites Marion
Drury Inn & Suites Marion
9.4 out of 10, Exceptional, (1005)
The price is P3,709
P4,451 total
includes taxes & fees
Sep 7 - Sep 8

Baymont by Wyndham Marion
Baymont by Wyndham Marion
8.2 out of 10, Very Good, (1034)
The price is P4,777
P5,732 total
includes taxes & fees
Aug 24 - Aug 25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Murphysboro
Barbecue enthusiasts flock to the Apple Festival and award-winning 17th Street BBQ for Southern Illinois' most celebrated smoked meats. Outdoor adventurers can explore nearby Kinkaid Lake's fishing spots or take a short drive to Shawnee National Forest's hiking trails.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Murphysboro Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
10/10 Excellent
More cheap stays in Murphysboro
More cheap stays in Murphysboro

Super 8 by Wyndham Marion
2601 Vernell Rd, Marion, IL
The price is P3,801 per night from Aug 18 to Aug 19
P3,801
P4,561 total
Aug 18 - Aug 19
includes taxes & fees
7.6/10 Good! (1,000 reviews)
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Near an Attraction
Hotel Theme
Hotels Near Murphysboro, Illinois
- Cape Girardeau Hotels
- Marion Hotels
- Carbondale Hotels
- Ozarks Hotels
- Southern Illinois Hotels
- Perryville Hotels
- Jackson Hotels
- Sparta Hotels
- Makanda Hotels
- Carterville Hotels
- Benton Hotels
- Du Quoin Hotels
- Cobden Hotels
- Anna Hotels
- Goreville Hotels
- Creal Springs Hotels
- Alto Pass Hotels
- Pinckneyville Hotels
- Chester Hotels
- West Frankfort Hotels
Most Popular Hotels in Murphysboro
More ways to book
Expedia's Latest Trends
Hotels