Photo by Southernmost Illinois Tourism Bureau
Murphysboro Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in Murphysboro
Family friendly
Pet friendly
Check prices for these dates
Top 10 trending Murphysboro hotels
Our top choices for Murphysboro hotels

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
9.4 out of 10, Exceptional, (467)
The price is P5,940
P6,592 total
includes taxes & fees
Sep 7 - Sep 8

Super 8 by Wyndham Carbondale
Super 8 by Wyndham Carbondale
7.2 out of 10, Good, (1008)
The price is P3,705
P4,260 total
includes taxes & fees
Aug 24 - Aug 25

Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHG
8.8 out of 10, Excellent, (597)
The price is P5,540
P6,370 total
includes taxes & fees
Sep 1 - Sep 2

Home2 Suites by Hilton Carbondale
Home2 Suites by Hilton Carbondale
8.8 out of 10, Excellent, (481)
The price is P8,204
P9,433 total
includes taxes & fees
Aug 27 - Aug 28

University Inn of Carbondale
University Inn of Carbondale
6.2 out of 10, (257)

Drury Inn & Suites Marion
Drury Inn & Suites Marion
9.4 out of 10, Exceptional, (1013)
The price is P3,712
P4,454 total
includes taxes & fees
Sep 7 - Sep 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Murphysboro
Barbecue enthusiasts flock to the Apple Festival and award-winning 17th Street BBQ for Southern Illinois' most celebrated smoked meats. Outdoor adventurers can explore nearby Kinkaid Lake's fishing spots or take a short drive to Shawnee National Forest's hiking trails.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Murphysboro Hotel Reviews

Super 8 by Wyndham Carbondale
10/10 Excellent
More cheap stays in Murphysboro
More cheap stays in Murphysboro

Super 8 by Wyndham Marion
2601 Vernell Rd, Marion, IL
The price is P3,804 per night from Aug 21 to Aug 22
P3,804
P4,564 total
Aug 21 - Aug 22
includes taxes & fees
7.6/10 Good! (1,002 reviews)
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Near an Attraction
Hotel Theme
Hotels Near Murphysboro, Illinois
- Cape Girardeau Hotels
- Marion Hotels
- Carbondale Hotels
- Ozarks Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Perryville Hotels
- Sparta Hotels
- Makanda Hotels
- Carterville Hotels
- Benton Hotels
- Du Quoin Hotels
- Goreville Hotels
- Anna Hotels
- Cobden Hotels
- Creal Springs Hotels
- Alto Pass Hotels
- Pinckneyville Hotels
- Chester Hotels
- Herrin Hotels
Most Popular Hotels in Murphysboro
More ways to book
Expedia's Latest Trends
Hotels