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Hotels near Mississippi River

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Check prices for these dates

This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Mississippi River hotels

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean rooms, comfy beds, nice pool and good variety at breakfast. Couldn’t ask for much more!"
United States
Sarah
The price is P6,936
P8,070 total
includes taxes & fees
Dec 6 - Dec 7
Sleep Inn & Suites Hannibal West
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

2. Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.8 out of 10, Excellent, (1,001 reviews)
"Location was great!"
United States
Rob
The price is P6,357
P7,333 total
includes taxes & fees
Nov 19 - Nov 20
Best Western On The River
A gazebo with a table and benches, surrounded by trees and a body of water.

3. River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
8.8 out of 10, Excellent, (395 reviews)
"Nice location."
United States
Jeff
The price is P5,250
P5,961 total
includes taxes & fees
Dec 8 - Dec 9
River's Edge Motel
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

4. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,007 reviews)
"Our go to hotel for years when we visit Hannibal."
United States
Gayle
The price is P4,226
P4,917 total
includes taxes & fees
Dec 6 - Dec 7
Quality Inn & Suites Hannibal West
A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

5. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.6 out of 10, Exceptional, (205 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is P9,593
P13,254 total
includes taxes & fees
Nov 16 - Nov 17
Riverside Inn Hannibal
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

6. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
71.8 km from Mississippi River
9.2 out of 10, Wonderful, (1,008 reviews)
"As always the stay was great"
United States
Peter
The price is P5,943
P6,773 total
includes taxes & fees
Dec 1 - Dec 2
Oak Hill Inn & Suites
A modern kitchen with wooden cabinets, a granite countertop, a coffee machine, a microwave, a toaster, and a refrigerator.

7. Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
47.8 km from Mississippi River
8.6 out of 10, Excellent, (486 reviews)
"Very nice clean friendly"
United States
paul
The price is P4,869
P5,550 total
includes taxes & fees
Nov 16 - Nov 17
Heritage Hotel Quincy
A hot tub with a rocky backdrop and a mural.

8. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
46.5 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
"The hotel was rustic, clean, and a great place to stay."
United States
Kent
The price is P4,783
P5,451 total
includes taxes & fees
Nov 22 - Nov 23
Stoney Creek Inn Quincy
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

9. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Excellent place to stay"
United States
Jared
The price is P3,650
P4,211 total
includes taxes & fees
Nov 21 - Nov 22
Motel 6 Hannibal, MO
A hotel room with a bed, a sofa, a desk, and a lamp.

10. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (776 reviews)
"Front desk helpful Clean rooms Great breakfast and lady fixing our breakfast was helpful and kept plenty of food ready for all"
United States
Jerry
The price is P4,423
P5,292 total
includes taxes & fees
Nov 25 - Nov 26
Comfort Inn & Suites - Hannibal
A hotel room with two beds, a wooden headboard, a nightstand with a phone, and a wall-mounted lamp.

11. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (299 reviews)
"Pretty good place to stay at with a great price !!"
United States
Christian
The price is P3,700
P4,268 total
includes taxes & fees
Nov 19 - Nov 20
Days Inn by Wyndham Hannibal
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

12. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,000 reviews)
"Clean, safe hotel and friendly staff"
United States
Julie
The price is P3,478
P4,012 total
includes taxes & fees
Nov 30 - Dec 1
Super 8 by Wyndham Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.

13. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
46.1 km from Mississippi River
8.8 out of 10, Excellent, (699 reviews)
"The hotel was in a great location with clean rooms."
United States
Colleen
The price is P7,148
P8,147 total
includes taxes & fees
Dec 13 - Dec 14
Holiday Inn Quincy East by IHG
A hotel room with a bed, a desk with a computer, a TV, and a bathroom with a shower.

14. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (499 reviews)
"Great stay for a wedding in the area."
United States
Bryan
The price is P7,275
P8,292 total
includes taxes & fees
Dec 13 - Dec 14
Quality Inn & Suites Quincy - Downtown
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

15. Lighthouse Inn & Suites

Lighthouse Inn & Suites
3.5 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (47 reviews)
"The room was very clean. It had a hot tub in it and it was also very clean and worked properly. We enjoyed our stay there."
United States
Connie
The price is P10,629
P12,261 total
includes taxes & fees
Nov 16 - Nov 17
Lighthouse Inn & Suites
A hotel lobby with a dining area, a bar, and a fireplace.

16. Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy
3.0 star property
46 km from Mississippi River
8.6 out of 10, Excellent, (366 reviews)
"Room was clean and staff was nice."
United States
Jeremy
The price is P7,437
P8,477 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites Quincy
A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

17. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
95.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"All the people were very nice and talkative. The happy hour food was good and so were the cocktails. The hotel was clean and comfortable."
United States
Michael
The price is P6,924
P7,959 total
includes taxes & fees
Nov 29 - Nov 30
Drury Inn & Suites St. Louis St. Peters
A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

18. Garden House Bed and Breakfast

Garden House Bed and Breakfast
3.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (57 reviews)
"Beautiful Queen Ann B&B, was reasonably priced and within walking distance to the river and down town Hannibal attractions."
United States
Debbie
The price is P6,712
P7,743 total
includes taxes & fees
Nov 22 - Nov 23
Garden House Bed and Breakfast
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

19. DoubleTree by Hilton Quincy

DoubleTree by Hilton Quincy
3.5 star property
47.9 km from Mississippi River
8.4 out of 10, Very good, (788 reviews)
"Rooms were very clean and the staff was amazing and very accommodating for all of our family. There were 10 different families and they made sure we were all in the same floor."
United States
Ronda
The price is P6,950
P7,922 total
includes taxes & fees
Dec 1 - Dec 2
DoubleTree by Hilton Quincy
A hotel room with a bed, a desk, a chair, a television, and a window with curtains.

20. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
2.5 star property
47.9 km from Mississippi River
7.6 out of 10, Good, (1,000 reviews)
"Nice place. Convenient location."
United States
Robert
The price is P4,815
P5,489 total
includes taxes & fees
Nov 18 - Nov 19
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.
Sleep Inn & Suites Hannibal West
2.5 star property
9.6
Exceptional
1,000 reviews
View
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
Best Western On The River
2.5 star property
8.8
Excellent
1,001 reviews
View
A gazebo with a table and benches, surrounded by trees and a body of water.
River's Edge Motel
2.0 star property
8.8
Excellent
395 reviews
View
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
Quality Inn & Suites Hannibal West
2.5 star property
8.0
Very good
1,007 reviews
View
A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.
Riverside Inn Hannibal
2.5 star property
9.6
Exceptional
205 reviews
View

Top Mississippi River Hotel Reviews

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

10/10 Excellent
"It was a perfect hotel for staying at the Airport with transportation to and from St. Louis International Hotel. The front desk staff were very helpful and friendly, especially the lady at the front desk on Tuesday morning. The workout room was pretty weak. But it did allow me to get a small workout completed while on this trip."
Charles 1-night trip
Posted less than an hour ago
Wingate by Wyndham St. Louis Airport

Other attractions near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this trendy area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.