Hotels near Mississippi River

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (361 reviews)
"Staff was really nice and helpful."
United States
rhonda
The price is P4,844
P5,500 total
includes taxes & fees
Apr 8 - Apr 9
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is P5,807
P6,593 total
includes taxes & fees
Apr 3 - Apr 4
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.2 out of 10, (750 reviews)
"staff was very helpful,motel was clean even though being older and in need of update,which is in progress,breakfast was very good .had a minor issue with room,but was taken care of quickly,did not use pool.motel is what I expected ."
United States
Richard
The price is P3,815
P4,412 total
includes taxes & fees
Apr 12 - Apr 13
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,012 reviews)
"Great hotel. Close to downtown. Walked to restaurant for dinner. "
United States
Bernadine R
The price is P6,116
P7,024 total
includes taxes & fees
Apr 19 - Apr 20
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (170 reviews)
"Great place to stay!"
United States
Sandy
The price is P9,779
P13,324 total
includes taxes & fees
Apr 2 - Apr 3
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"Would highly recommend to anyone needed an excellent hotel"
United States
Elizabeth
The price is P7,442
P8,622 total
includes taxes & fees
Apr 5 - Apr 6
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Good stay. "
United States
Ted
The price is P4,130
P4,871 total
includes taxes & fees
Apr 19 - Apr 20
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is P10,347
P13,969 total
includes taxes & fees
Apr 2 - Apr 3
Lighthouse Inn & Suites

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (523 reviews)
"I had to pass numerous tweakers on the way to this sight. The pictures provided are NOT of this hotel. When I checked in, I was instructed to go downstairs.... to room 313. I never even went in the room. After I got dinner, I started looking at reviews of the hotel that were not on expedia.... and discovered it had a 1.6 star review. The FIRST comment I read was about room 313.... How the air conditioner filter was nasty, the bedding wasn't changed and the overall nastiness of the place. It's...
United States
Kaylee
The price is P4,239
P4,809 total
includes taxes & fees
Apr 1 - Apr 2
Economy Inn Wentzville

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very Good, (40 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is P5,837
P6,704 total
includes taxes & fees
Apr 19 - Apr 20
Garden House Bed and Breakfast

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (682 reviews)
"The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location. "
United States
Kayleigh
The price is P5,348
P6,325 total
includes taxes & fees
Apr 19 - Apr 20
Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,006 reviews)
"Great stay. Very comfortable beds!"
United States
Kari
The price is P5,098
P5,906 total
includes taxes & fees
Apr 5 - Apr 6
Quality Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is P4,057
P4,659 total
includes taxes & fees
Apr 8 - Apr 9
Motel 6 Hannibal, MO

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (229 reviews)
"Clean room. Comfortable bed. The staff were friendly. Convenient on/off location."
United States
Helen
The price is P3,860
P4,434 total
includes taxes & fees
Apr 8 - Apr 9
Days Inn by Wyndham Hannibal

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (501 reviews)
"Ok stay"
United States
Timothy
The price is P3,979
P4,456 total
includes taxes & fees
Apr 5 - Apr 6
Baymont by Wyndham Keokuk

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (40 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is P4,099
P4,630 total
includes taxes & fees
Apr 5 - Apr 6
LAKEVIEWINN

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,000 reviews)
"Clean rooms, easy check in, friendly staff, awesome location "
United States
Rhonda
The price is P3,815
P4,382 total
includes taxes & fees
Apr 26 - Apr 27
Super 8 by Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,005 reviews)
"Enjoy our stay very nice clean neat breakfast fresh and staff helpful and pleasant "
United States
Tatiana
The price is P4,181
P5,111 total
includes taxes & fees
Apr 5 - Apr 6
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (161 reviews)
"Pet friendly, clean room, great staff and delicious breakfast "
United States
Melissa
The price is P3,452
P3,992 total
includes taxes & fees
Apr 1 - Apr 2
Howard Johnson BY Wyndham Hannibal

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (526 reviews)
"Listing was completely false there is no pool that will ever be operational supposed to be a suite that sleeps 4 but hide a bed had no bedding and when I asked for some all they would give me was 2 very old thin blankets no sheet no pillow both the other beds were stained and dirty there was no toilet paper windows were boarded up on building and was just not what they represented online "
United States
Levi
The price is P4,733
P5,440 total
includes taxes & fees
Apr 6 - Apr 7
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
361 reviews
View
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
22 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.2
750 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,012 reviews
View
Egyptian cotton sheets, premium bedding, pillowtop beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
170 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Near Union Station and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.