Hotels near Mississippi River

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Our top choices for Mississippi River hotels

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is P5,556
P6,308 total
includes taxes & fees
Feb 15 - Feb 16
The Eagles Nest Inn

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (359 reviews)
"Excellent stay !!! Quite "
United States
Bradley
The price is P4,649
P5,278 total
includes taxes & fees
Feb 15 - Feb 16
River's Edge Motel

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (740 reviews)
"Thanks to the staff very help and kind. Very good stay. "
United States
Terry
The price is P3,395
P3,925 total
includes taxes & fees
Feb 17 - Feb 18
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,002 reviews)
"Everything was great. Will definitely stay again."
United States
Ethan
The price is P3,765
P4,324 total
includes taxes & fees
Feb 16 - Feb 17
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (167 reviews)
"Great place to stay!"
United States
Sandy
The price is P8,256
P11,481 total
includes taxes & fees
Feb 15 - Feb 16
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
"It was a good midway stop for us on our way to Memphis."
United States
Joel
The price is P5,693
P6,595 total
includes taxes & fees
Feb 22 - Feb 23
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is P3,754
P4,428 total
includes taxes & fees
Feb 21 - Feb 22
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (517 reviews)
"The heating unit was noise, the sink was plumbed backwards but the room was clean."
United States
Gordon
The price is P3,482
P3,950 total
includes taxes & fees
Feb 15 - Feb 16
Economy Inn Wentzville

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Clean room very nice staff it’s nice"
United States
Mercedez
The price is P3,656
P4,201 total
includes taxes & fees
Feb 20 - Feb 21
Relax Inn Saint Charles

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Nice room. Matched the pictures. Exactly what we were looking for."
United States
John
The price is P9,798
P11,254 total
includes taxes & fees
Feb 18 - Feb 19
Lighthouse Inn & Suites

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.6 out of 10, Excellent, (38 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is P6,215
P7,138 total
includes taxes & fees
Feb 15 - Feb 16
Garden House Bed and Breakfast

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is P3,556
P4,088 total
includes taxes & fees
Mar 1 - Mar 2
Days Inn by Wyndham St Peters/St Charles

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (673 reviews)
"Everything was clean and staff was friendly. Just needed some updates. "
United States
Georgia
The price is P4,410
P5,239 total
includes taxes & fees
Feb 24 - Feb 25
Comfort Inn & Suites - Hannibal

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (497 reviews)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
The price is P4,079
P4,568 total
includes taxes & fees
Feb 27 - Feb 28
Baymont by Wyndham Keokuk

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,000 reviews)
"Great staff and the place is nice and clean and the breakfast is awesome."
United States
Kerry
The price is P3,403
P4,160 total
includes taxes & fees
Mar 1 - Mar 2
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,008 reviews)
"Good breakfast selections. Close to a good restaurant. "
United States
Steve
The price is P4,074
P4,719 total
includes taxes & fees
Feb 22 - Feb 23
Quality Inn & Suites Hannibal West

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (34 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is P3,917
P4,424 total
includes taxes & fees
Feb 15 - Feb 16
LAKEVIEWINN

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Overall, very nice stay"
United States
Cary
The price is P3,191
P3,664 total
includes taxes & fees
Mar 5 - Mar 6
Motel 6 Hannibal, MO

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,000 reviews)
"clean room - soft beds - friendly staff - very welcoming - lobby nice"
United States
Maxine
The price is P3,308
P3,799 total
includes taxes & fees
Feb 15 - Feb 16
Super 8 by Wyndham Hannibal

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (521 reviews)
"The staff was very helpful the rooms where nice very affordable clean and very quiet"
United States
Valerie
The price is P3,983
P4,578 total
includes taxes & fees
Mar 8 - Mar 9
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
21 reviews
View
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
359 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
740 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,002 reviews
View
Egyptian cotton sheets, premium bedding, pillowtop beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
167 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. You'll find it 76 mi (122.3 km) from Mississippi River. Other good options around the area include 21C Museum Hotel St Louis and Hilton St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.