Hotels near Mission Hope Cancer Center

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Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Mission Hope Cancer Center hotels

Reception
Hotel Avanti

Hotel Avanti

Hotel Avanti
2.5 star property
2.3 km from Mission Hope Cancer Center
9.0 out of 10, Wonderful, (282)
"The rooms were surprisingly nice. "
United States
mario
The price is P4,897
P5,510 total
includes taxes & fees
Dec 28 - Dec 29
Hotel Avanti
Restaurant
Best Western Plus Big America

Best Western Plus Big America

Best Western Plus Big America
2.5 star property
2.8 km from Mission Hope Cancer Center
8.8 out of 10, Excellent, (1001)
"Room was fabulous as was the staff."
United States
Laura
The price is P6,402
P7,202 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Big America
Restaurant
Historic Santa Maria Inn

Historic Santa Maria Inn

Historic Santa Maria Inn
3.5 star property
2.2 km from Mission Hope Cancer Center
8.4 out of 10, Very Good, (1860)
"Nice place to stay "
United States
octaviano
The price is P4,601
P5,176 total
includes taxes & fees
Dec 28 - Dec 29
Historic Santa Maria Inn
Reception
ECONOMY INN

ECONOMY INN

ECONOMY INN
2.5 star property
2.1 km from Mission Hope Cancer Center
8.0 out of 10, Very Good, (74)
"Decent hotel for the price"
United States
ydalid
The price is P3,066
P3,449 total
includes taxes & fees
Dec 30 - Dec 31
ECONOMY INN
Desk, free WiFi
Villa Motel

Villa Motel

Villa Motel
2.0 star property
2.4 km from Mission Hope Cancer Center
8.0 out of 10, Very Good, (174)
"Staff was very friendly "
United States
erika
The price is P3,818
P4,295 total
includes taxes & fees
Dec 26 - Dec 27
Villa Motel
Premium bedding, in-room safe, blackout drapes, iron/ironing board
Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria
2.0 star property
2.9 km from Mission Hope Cancer Center
7.8 out of 10, Good, (1001)
"Great establishment and surrounding neighborhood. "
United States
Julio
The price is P5,791
P6,515 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Travelodge by Wyndham Santa Maria
Outdoor pool
Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria
2.0 star property
0.8 km from Mission Hope Cancer Center
6.8 out of 10, (1000)
"Room was clean staff was nice. "
United States
Kimberly Dawn
The price is P4,193
P4,718 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Santa Maria
View from property
Buckboard Motel

Buckboard Motel

Buckboard Motel
2.5 star property
3 km from Mission Hope Cancer Center
6.8 out of 10, (71)
"Excellent place to rest excellent price "
United States
Carlos
The price is P3,671
P4,129 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Buckboard Motel
Lobby
Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South
2.0 star property
0.5 km from Mission Hope Cancer Center
5.8 out of 10, (511)
"Room was nice and the owner and staff were helpful and kind."
United States
Jason
The price is P4,492
P5,054 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Motel 6 Santa Maria, CA - South
Reception
Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria
2.5 star property
3.7 km from Mission Hope Cancer Center
9.4 out of 10, Exceptional, (1000)
"Breakfast very good, Parkin field safe ,the room very clean"
United States
Hugo
The price is P6,970
P7,855 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Santa Maria
Front of property - evening/night
Wine Stone Inn

Wine Stone Inn

Wine Stone Inn
5.0 star property
10.2 km from Mission Hope Cancer Center
9.8 out of 10, Exceptional, (600)
"Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. "
United States
shannon
The price is P9,249
P11,006 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wine Stone Inn
Property amenity
Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (726)
"Clean room and great staff and service! "
United States
Ruby
The price is P6,578
P7,413 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fairfield Inn & Suites by Marriott Santa Maria
Restaurant
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria
3.0 star property
3.5 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (40)
"Room was great and the staff were extremely courteous and helpful! Can't wait to stay there again."
United States
John
The price is P5,924
P6,676 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Homewood Suites by Hilton Santa Maria
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1000)
"Clean room . Great stay"
United States
Derek
The price is P5,580
P6,277 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Candlewood Suites Santa Maria by IHG
Check-in/check-out kiosk
Solaire Inn & Suites

Solaire Inn & Suites

Solaire Inn & Suites
2.5 star property
3.6 km from Mission Hope Cancer Center
8.2 out of 10, Very Good, (1000)
"Clean Staff very helpful "
United States
Sally
The price is P3,700
P4,163 total
includes taxes & fees
Dec 28 - Dec 29
Solaire Inn & Suites
Pet-friendly amenities
Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North
2.0 star property
3.4 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1009)
"Great staff and the room was clean"
Canada
Adam
The price is P2,899
P3,271 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Motel 6 Santa Maria, CA - North
Outdoor pool
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

Radisson Hotel Santa Maria
3.5 star property
6.8 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1331)
"Staff was great . They were very welcoming made the stay comfortable "
United States
Luis
The price is P5,791
P6,515 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Radisson Hotel Santa Maria
Desk, free WiFi, bed sheets, wheelchair access
Colonial Motel

Colonial Motel

Colonial Motel
2.0 star property
3.4 km from Mission Hope Cancer Center
6.4 out of 10, (164)
"I recomendar this place "
United States
Everarda
The price is P4,385
P4,933 total
includes taxes & fees
Dec 29 - Dec 30
Colonial Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Hope Cancer Center Hotel Reviews

Historic Santa Maria Inn

Historic Santa Maria Inn

10/10 Excellent
"clean and quickly fixed the toilet."
Jung-A 1-night trip
Posted 3 days ago
Historic Santa Maria Inn

Hotels near other Mission Hope Cancer Center attractions

Pacific Conservatory Theatre

You can get tickets for a performance at Pacific Conservatory Theatre during your stay in Santa Maria. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Simas Park

After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, check out the 6 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveler data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Another good option is Hampton Inn & Suites Santa Maria, located 2.3 mi (3.7 km) away.
How many hotels are there near Mission Hope Cancer Center?
Expedia has 6 hotels and other accommodations within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Mission Hope Cancer Center.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum, or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Santa Maria Valley Discovery Museum, Rancho Bowl, and Santa Maria Fairpark are fun stops for the whole family while you're in town.