What is Midtown like?

Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveler data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 36 Midtown hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.

What are the top things to see and do in Midtown?

Sights like Red Flag, Scott Joplin House State Historic Site, and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighborhood. St. Louis Union Station, Hermann Stadium, and .ZACK Theater are just a few of the places to visit in and around Midtown. While you're out sightseeing, Fubar and The Sovereign - St. Louis are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

Midtown Hotels, St. Louis

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Our top choices for Midtown hotels

An outdoor patio area with seating, planters, and a grill.

1. Element by Marriott St. Louis Midtown

Midtown

Julie

P10,525 total

includes taxes & fees

Nov 19 - Nov 20

An outdoor patio area with seating, a fire pit, and a grill.

2. Residence Inn by Marriott St Louis Downtown

Midtown

Kirsten

P8,235 total

includes taxes & fees

Nov 23 - Nov 24

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

Pamela

P8,282 total

includes taxes & fees

Nov 22 - Nov 23

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Stephanie

P7,671 total

includes taxes & fees

Nov 25 - Nov 26

A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

5. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

A.R.

P10,889 total

includes taxes & fees

Dec 9 - Dec 10

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

6. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Samuwel

P7,699 total

includes taxes & fees

Nov 15 - Nov 16

An indoor pool area with a hot tub, seating, and a stone wall.

7. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

gina

P8,508 total

includes taxes & fees

Nov 15 - Nov 16

A modern outdoor seating area with a fire pit, surrounded by wicker furniture and a landscaped garden.

8. Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Midtown

nadia

P8,545 total

includes taxes & fees

Nov 25 - Nov 26

A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

9. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West, 1.7 km from Midtown

William

P11,602 total

includes taxes & fees

Nov 25 - Nov 26

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

10. Comfort Inn & Suites Saint Louis Lafayette Square

The Gate, 2 km from Midtown

Michelle

P8,039 total

includes taxes & fees

Dec 11 - Dec 12

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

11. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 3 km from Midtown

Ruth

P10,635 total

includes taxes & fees

Dec 6 - Dec 7

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

12. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

brandon

P10,406 total

includes taxes & fees

Nov 25 - Nov 26

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

13. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

Tracy

P8,400 total

includes taxes & fees

Nov 27 - Nov 28

An outdoor dining area with a glass table and chairs, a neon sign, and a city view.

14. Aloft by Marriott St Louis Central West End

Central West End, 2.2 km from Midtown

Brittany

P8,383 total

includes taxes & fees

Nov 25 - Nov 26

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

15. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Andrew

P7,786 total

includes taxes & fees

Nov 25 - Nov 26

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Megan

P7,890 total

includes taxes & fees

Dec 10 - Dec 11

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

17. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

Arthur

P5,475 total

includes taxes & fees

Dec 11 - Dec 12

A rooftop terrace with wicker furniture, offering a city view.

18. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Nicole

P10,598 total

includes taxes & fees

Nov 25 - Nov 26

A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

19. The Westin St. Louis

Downtown St. Louis, 2.9 km from Midtown

Stacy

P9,003 total

includes taxes & fees

Nov 25 - Nov 26

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

20. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 3.6 km from Midtown

Sara

P12,992 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels in Midtown

Property	Property class	Guest rating
Element by Marriott St. Louis Midtown	3.0 star property	8.8 Excellent 859 reviews	View
Residence Inn by Marriott St Louis Downtown	3.0 star property	7.6 Good 1,000 reviews	View
Fairfield Inn & Suites by Marriott St. Louis Downtown	3.0 star property	9.2 Wonderful 1,007 reviews	View
Drury Plaza Hotel St. Louis Union Station	3.0 star property	9.4 Exceptional 1,618 reviews	View
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton	4.0 star property	8.8 Excellent 1,175 reviews	View

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Midtown Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Nachos and drinks at happy hour. Full hot breakfast. Lovely room"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"The room was very clean; the cleaning staff was somewhat hesitant to provide me with extra towels and wash cloths upon request. The breakfast bar was very nice; however, on the weekend the omlet bar was not opened until 7:00am (omlets were cooked to specification). You could not carry food out to your room or fix a plate to take with you on the road. This was very inconveient for me as I needed to leave hotel by 6:30am to drive to St. Louis Convention Center 20 miles away, park in 9th St garage and walk to 11th St to the Convention Center for morning services at 7am. It would have been nice to have been able to take a cup of fruit with me. The hotel had lots of garage parking; however, there were no lights in the garage except a flood light by the door entrance that led into the hotel. Parking at night was uncanningly frightening because once you parked your car, if you were not close to the flood light that lit up the door entrance or didn't have a flash light, it was pitch black. Thankfully, I had a very powewrful flashlight I keep in my car which came in handy. The hotel does not provide any other dining other than breakfast."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Hi, always have a great stay at Drury Inn. It's always my first pick when coming to St Louis. The staff are always nice and very helpful. My room was clean and very spacious.I love the complimentary happy hour and appetizers. Popcorn is the best! Just wish hot chocolate was an pption at the coffee station. Onsite parking was convient. I will definitely be back again"

Midtown Hotels near St. Louis

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Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

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Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

5. 21C Museum Hotel St Louis

6. Pear Tree Inn St. Louis Near Union Station

7. Drury Plaza Hotel St. Louis Union Station

8. Courtyard by Marriott St. Louis Downtown West

9. St. Louis Union Station Hotel, Curio Collection by Hilton

10. Comfort Inn & Suites Saint Louis Lafayette Square

11. Home2 Suites by Hilton St. Louis/Forest Park

12. Live by Loews - St.Louis

13. Hyatt Regency St. Louis at The Arch

14. Aloft by Marriott St Louis Central West End

15. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

16. Embassy Suites by Hilton St. Louis Downtown

17. Tru By Hilton St. Louis Downtown

18. Drury Plaza Hotel St. Louis at the Arch

19. The Westin St. Louis

20. The Royal Sonesta Chase Park Plaza St. Louis

Compare popular hotels in Midtown

Where to stay in Midtown

Downtown St. Louis

Clayton

St. Charles Historic District

Central West End

Creve Coeur

Top Midtown Hotel Reviews

Pear Tree Inn St. Louis Airport

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