Mesopotamia Hotels

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Top 10 trending Mesopotamia hotels

To Spiti tis Sofias
Relax in a spacious living area with a high ceiling, comfortable seating, and a fireplace.

To Spiti tis Sofias

The price is P3,845
P4,502 total
includes taxes & fees
Aug 18 - Aug 19
To Spiti tis Sofias
Guest House Ilektra
Stroll through the serene landscape, surrounded by lush greenery and rolling hills, to this charming two-story building with a stone staircase and black shutters.

Guest House Ilektra

9.8 out of 10, Exceptional, (6)
"We were doing a project in nearby Pentalofos so we had long work days. The area is quiet and it's a wonderful departure from the business of the city. The rooms were quite comfortable and my room had everything I needed. I had a small fridge and a stove to cook up anything if I wanted. Part way through my trip I was able to coordinate laundry services. My room had a wonderful view of the sunrise, which was a great sight to wake up to. The rooms are always clean and warm, it felt like a home...
The price is P2,967
P3,504 total
includes taxes & fees
Aug 4 - Aug 5
Guest House Ilektra
Limneon Resort & Spa
Enjoy a serene meal with a view of the mountains and water from this dining area.

Limneon Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (184)
"Wonderful stay. "
The price is P5,607
P7,042 total
includes taxes & fees
Sep 1 - Sep 2
Limneon Resort & Spa
Hotel Anastassiou
Welcome to Hotel, where guests can dine or relax in the outdoor seating areas surrounded by beautifully maintained gardens.

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very Good, (66)
"Nice hotel. Nice room. Nice people!! Not walkable to town but a very short drive! And a very lovable property pup!! Thank you for your hospitality!! "
The price is P2,967
P3,504 total
includes taxes & fees
Aug 4 - Aug 5
Hotel Anastassiou
Orologopoulos Mansion
Relax in a traditional bedroom with a large bed, frosted glass windows, and a wooden nightstand.

Orologopoulos Mansion

5.0 star property
9.6 out of 10, Exceptional, (33)
"Wonderful Boutique hotel in center of old town"
Orologopoulos Mansion
Anesis Hotel
Stroll along the riverside walkway, lined with seating areas and surrounded by lush greenery.

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
The price is P3,264
P3,841 total
includes taxes & fees
Aug 4 - Aug 5
Anesis Hotel
Kyknos De Luxe Hotel
Relax in this serene hotel room with a large bed, sliding glass door to a poolside view, and comfortable seating area.

Kyknos De Luxe Hotel

10.0 out of 10, Exceptional, (42)
"Very nice clean, very polite staff and great breakfast!"
The price is P5,044
P6,065 total
includes taxes & fees
Aug 27 - Aug 28
Kyknos De Luxe Hotel
Esperos Palace Luxury & Spa Hotel
Enjoy dining in this spacious interior with a central tree-like structure, tables, and chairs.

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
"Gorgeous and spacious. Very classy and modern. I've stayed here twice and will definitely go back. "
The price is P6,201
P7,716 total
includes taxes & fees
Aug 4 - Aug 5
Esperos Palace Luxury & Spa Hotel
Chloe Hotel
Enjoy a delicious breakfast amidst lush surroundings.

Chloe Hotel

3.0 star property
10.0 out of 10, Exceptional, (84)
"We enjoyed the stay, friendly staff and nice breakfast "
The price is P5,934
P7,076 total
includes taxes & fees
Aug 4 - Aug 5
Chloe Hotel
Guesthouse Vissinokipos
Surrounded by lush greenery, this serene home features a two-story house with a balcony and a tranquil outdoor space.

Guesthouse Vissinokipos

9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
Guesthouse Vissinokipos
Calma Hotel & Spa
Relax by the resort's large pool surrounded by lush greenery and distant mountains.

Calma Hotel & Spa

4.0 star property
9.6 out of 10, Exceptional, (34)
"Great place to relax. Very kind staff all over. Nice breakfast buffet."
Calma Hotel & Spa
Arhontiko Christodoulou
Stunning mountain retreat with a central entrance and two-story facade, surrounded by snow-covered trees and a mountainous backdrop.

Arhontiko Christodoulou

2.0 star property
Arhontiko Christodoulou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesopotamia

Head to Kastoria Lake and Dragon's Lair—just two of the sights around Mesopotamia.

See all hotels in Mesopotamia

Top Mesopotamia Hotel Reviews

Limneon Resort & Spa

Limneon Resort & Spa

10/10 Excellent
"Incredibly beautiful property. The view is stunning, the pools are amazing! The rooms were nice and quiet, well sound proofed and the curtains were nice and darkened if you needed to sleep in late. Unfortunately I wasn't able to visit the spa but it looked amazing and I'm sure, like everything else it was exactly as shown and described. Highly recommend!"
April Dawn 5-night trip
Posted 5 days ago
Limneon Resort & Spa

Frequently asked questions

Where is the best place for a stay in Mesopotamia?

To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.

If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?

Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.

Where can I learn more about changing or cancelling my trip to Mesopotamia?

For more details about picking new dates or cancelling your trip to Mesopotamia, click here.

What are some hotels with pools in Mesopotamia?

Limneon Resort & Spa: Features an indoor pool, an outdoor pool, and a sauna. Calma Hotel & Spa and Loggas Hotel are a couple of other choices with an onsite pool.

What is the best accommodation for staying close to Macedonia Airport (SKG)?

Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.

What is staying in Mesopotamia like?

Travelers to Mesopotamia will find plenty to explore and enjoy. There are 44 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.

What are the top places to visit in Mesopotamia?

Places to visit in the wider area include Kastoria Lake, Dragon's Lair, and Holy Monastery of Panagias Mauriotissas. You'll also find Kastoria Aquarium and Folklore Museum of Kastoria in the area. Check out what more to see and do in Expedia's Mesopotamia guide.

What's the seasonal weather like in Mesopotamia?

The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.