Hotels near Mercy Hospital Jefferson

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mercy Hospital Jefferson hotels

Free buffet breakfast
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
2.1 km from Mercy Hospital Jefferson
9.4 out of 10, Exceptional, (703)
"Clean, spotless, great room, front desk staff was excellent! Parking great!"
United States
Rick
The price is P7,696
P8,800 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Lobby
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
2.1 km from Mercy Hospital Jefferson
8.0 out of 10, Very Good, (893)
"Breakfast was great! Location right off interstate was perfect. The property is a little old."
United States
Mindy
The price is P5,443
P6,224 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby sitting area
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
2.3 km from Mercy Hospital Jefferson
7.8 out of 10, Good, (911)
"Vary clean"
United States
George
The price is P4,444
P5,193 total
includes taxes & fees
Dec 29 - Dec 30
Comfort Inn Festus - St Louis South
Meeting facility
Baymont by Wyndham Festus

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
1.8 km from Mercy Hospital Jefferson
6.8 out of 10, (924)
"Room was clean and comfortable for an overnight stay"
United States
Jack
The price is P4,759
P5,441 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Baymont by Wyndham Festus
Gift shop
Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
14.3 km from Mercy Hospital Jefferson
9.0 out of 10, Wonderful, (154)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is P7,556
P8,386 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Corner George Inn Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mercy Hospital Jefferson Hotel Reviews

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent
"Room was clean, air worked good, staff was super nice."
Jessica 2-night trip
Posted 6 days ago
Wingate by Wyndham St. Louis/Fenton Route 66

Hotels near other Mercy Hospital Jefferson attractions

Tranquil autumn landscape along the Osage River and Lake Ozarks in Missouri, United States

Sunset Park

After visiting Sunset Park, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants.
See properties
Flowering Red Bud tree, with purple buds, sidewalk, and historic black iron fence at Lafayette Park in St. Louis, Missouri.

West City Park

After visiting West City Park, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants.
See properties

Frequently asked questions

What's the area like around Mercy Hospital Jefferson?
Mercy Hospital Jefferson is located in Crystal City. You'll find 11 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay near Mercy Hospital Jefferson?
La Quinta Inn & Suites by Wyndham Festus - St. Louis South is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 1.3 mi (2.1 km) from Mercy Hospital Jefferson. Other good choices within 5 miles include Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG and Comfort Inn Festus - St Louis South.
How many hotels will I be able to find close to Mercy Hospital Jefferson?
Expedia has 11 hotels and other accommodations a few miles from Mercy Hospital Jefferson.
If I need to cancel the hotel reservation for my stay near Mercy Hospital Jefferson, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best options available near Mercy Hospital Jefferson.