Mendoza Wine Region Trips (flight + hotel)

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Where to stay in Mendoza Wine Region

Find the best Mendoza Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mendoza Wine Region
A large, multi-level auditorium with red seating and multiple balconies.

Mendoza City Center

6 out of top 10 points of interest in this area

Wineries, casinos, and spas highlight some notable features of Mendoza City Center. Make a stop by Chile Square or Plaza Italia while you're visiting, and jump aboard the metro at Mendoza Station or Belgrano Station to get around town.

Find hotels in Mendoza City Center

Top hotels in Mendoza Wine Region

Park Hyatt Mendoza

Park Hyatt Mendoza

5 out of 5
Chile 1124 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
The price is P13,965 per night from Nov 17 to Nov 18
P13,965
P13,965 total
Nov 17 - Nov 18
9.2/10 Wonderful! (1,005 reviews)
"Good hotel for visiting the wine bodegas but also having a taste of the city"

Reviewed on Nov 3, 2026

Park Hyatt Mendoza
Sheraton Mendoza Hotel

Sheraton Mendoza Hotel

4.5 out of 5
Primitivo De La Reta 989 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
The price is P8,743 per night from Dec 1 to Dec 2
P8,743
P8,743 total
Dec 1 - Dec 2
9.2/10 Wonderful! (1,000 reviews)
"Good hotel, but it's outdated and some rooms need work. Beds and pillows weren't really comfortable. You can't add the points to your Marriott account if you book through Expedia."

Reviewed on Nov 1, 2026

Sheraton Mendoza Hotel
Huentala Hotel

Huentala Hotel

4 out of 5
Primitivo De La Reta 1007 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
The price is P7,118 per night from Nov 8 to Nov 9
P7,118
P7,118 total
Nov 8 - Nov 9
8.6/10 Excellent! (994 reviews)
"Well located hotel which looks plush from the outside but tired in places."

Reviewed on Oct 28, 2026

Huentala Hotel
See all 1,042 properties in Mendoza Wine Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mendoza Wine Region attractions

A long wooden table with chairs, a wine glass, and barrels in the background.

Catena Zapata Winery

9.4/10 (73 reviews)
Taste award-winning wines and tip your glass to the Catena family at one of the world’s leading wineries, famous for its high altitude and Malbec vintages.
See properties

What to do in Mendoza Wine Region

High Mountain, Aconcagua and Inca Bridge

High Mountain, Aconcagua and Inca Bridge

P4,073
per adult
High Mountain, Aconcagua and Inca Bridge
Vistandes Winery

Wine and Olivicola Tour Wine and Oil Tastings

P2,135
per adult
Wine and Olivicola Tour Wine and Oil Tastings
From Mendoza: High Andes Aconcagua Mountain Tour

From Mendoza: High Andes Aconcagua Mountain Tour

P4,135
per adult
From Mendoza: High Andes Aconcagua Mountain Tour
See all activities in Mendoza Wine Region

Frequently asked questions

How much does a Mendoza Wine Region vacation package cost?
Starting from as low as , a vacation package is your portal to cheap travel. Build your own Mendoza Wine Region escape by picking from our huge range of hotels, airfares and rental cars.
How do I get a cheap travel package to Mendoza Wine Region?
One of the simplest ways to save money (and time) is to combine your bookings with Expedia. Hotels, flights, activities and rental cars — we've got it all. Pick and choose the combination that suits you and watch your savings grow. We know a package deal is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotels throughout the world, which lets you customize your Mendoza Wine Region vacation.
Where should I stay in Mendoza Wine Region?
For many visitors, Historic Center is the top pick. With great attractions like Independence Square, this neighborhood is a wonderful introduction to Mendoza Wine Region. Of course, staying in Mendoza City Center is also a fantastic idea. Independence Square is one awesome sight to cross off here.
What are the top hotels in Mendoza Wine Region?
If you'd like to stay in the Mendoza City Center neighborhood, some of your best options are Park Hyatt Mendoza and Villaggio Hotel. Historic Center is also a favorite Mendoza Wine Region area. We recommend Diplomatic Hotel or Sheraton Mendoza Hotel if you prefer this part of town.
How far in advance should I book my Mendoza Wine Region vacation?
Browse Expedia to compare airfares as soon as you know your travel dates. You can generally purchase a seat up to 12 months in advance. If it's too early for your preferred air carrier, or you're booking late, don't stress. Cheap tickets to Mendoza Wine Region occasionally appear just weeks before departure.
What does an Expedia Mendoza Wine Region travel package include?
It comes down to what you're after. If you're traveling solo, you might decide to bundle hotels and flights. Bringing the whole family to Mendoza Wine Region? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to build your own travel package.
What should I know before booking a Mendoza Wine Region travel package?
An Expedia travel package can be customized for your budget and is an easy way to stretch your dollars further. What you include is up to you. Rental cars, hotels and flights — decide on a combination that works with your plans.
Can I choose my airline with a Mendoza Wine Region Expedia vacation package?
Yes, and with over 550 airlines to choose from across the globe, you have loads of choice. Take a look at the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Mendoza Wine Region vacation package?
It is possible to cancel your Mendoza Wine Region booking if your travel plans have changed. Whether you'll incur a penalty or not depends on your airline, hotel or car rental company. It may be possible to change or cancel your booking free of charge if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.