A person wearing a straw hat and red bikini, standing on a beach with waves and a rocky cliff in the background.

Luxury Hotels in Megalochori, Santorini

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Megalochori Luxury Hotels

Tonight
Oct 4 - Oct 5
Tomorrow
Oct 5 - Oct 6
Next weekend
Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Our top choices for Megalochori luxury hotels

A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and distant islands.
An underground restaurant with stone walls and vaulted ceilings, featuring tables set for dining with candles and wine glasses.
A cozy interior with a dining area, seating, and a view to the outside.
A modern bedroom with a large window, a bed, a chair, and a TV.

1. Vedema, a Luxury Collection Resort, Santorini

Vedema, a Luxury Collection Resort, Santorini
Santorini
  • Santorini beachfront luxury with private shore access, full-service spa, and three restaurants creates an indulgent Mediterranean retreat.
P18,970
P22,599 total
includes taxes & fees
Oct 17 - Oct 18
Vedema, a Luxury Collection Resort, Santorini
A modern pool area with lounge chairs, a bar, and a staircase leading to upper levels.
A spa room with a hot tub, arched alcoves, and a view of the cityscape.
A modern outdoor seating area with a view of the sea, a pool, and a clear sky.
A modern bedroom with a large bed, a wooden accent wall, a large window with a view, and a small bedside table with a vase.

2. Enarma Suites & Spa Wellness Retreat

Enarma Suites & Spa Wellness Retreat
Santorini
  • Santorini wellness retreat pampers guests with Mediterranean dining, poolside relaxation, and indulgent spa therapies near the caldera.
P13,256
P16,111 total
includes taxes & fees
Oct 9 - Oct 10
Enarma Suites & Spa Wellness Retreat
A rooftop terrace with two hot tubs, a seating area, and a view of the sea at night.
A bedroom with a bed, a bedside table, and a view of the sea.
A spacious dining area with a chandelier, wooden chairs, a table with a vase of flowers, and large windows offering a view.
A kitchen with a wooden countertop, a sink, and a backsplash with intricate tile patterns. There are shelves above the countertop holding various items.

3. Caldera's Dolphin Suites

Caldera's Dolphin Suites
Santorini
P7,961
P9,181 total
includes taxes & fees
Oct 29 - Oct 30
Caldera's Dolphin Suites
A balcony with a view of a city at night, a bench, a table with a bottle and glass, and a lit lantern.
A room with a wooden table, a bottle of wine, and a glass of wine. There is a bowl of tomatoes on the table.
A modern living room with a sofa, a potted plant, and a fruit basket on a wooden table.
A modern outdoor seating area with a glass-top table and a glass of white wine, overlooking a cityscape and a sunset.

4. Aspronisi Luxury Villa

Aspronisi Luxury Villa
Santorini
P9,895
P11,378 total
includes taxes & fees
Oct 18 - Oct 19
Aspronisi Luxury Villa
An aerial view of a resort with multiple swimming pools, a desert landscape, and a city in the background.
An indoor pool with a circular shape, surrounded by stone walls and candles.
A modern hotel room with a large bed, a flat-screen TV, a dining area with a table and chairs, and a balcony with a view of the landscape.
A bedroom with a large bed, a view of the sea through an open door, a round mirror, and a small table with decorative items.

5. North Santorini - A Luxury Spa Hotel

North Santorini - A Luxury Spa Hotel
Santorini
P27,748
P32,568 total
includes taxes & fees
Oct 7 - Oct 8
North Santorini - A Luxury Spa Hotel
A view from a bathtub to a sunset over water, with a clear sky and distant land.
A white building with a curved staircase and a view of the sea.
A sun lounger with a view of the ocean and a boat in the distance.
A wooden four-poster bed with white curtains, positioned on a balcony overlooking a coastal landscape with mountains and the sea.

6. Celestia Grand

Celestia Grand
Santorini
P28,584
P32,743 total
includes taxes & fees
Nov 1 - Nov 2
Celestia Grand
A modern house with a swimming pool, outdoor seating, and a staircase leading to a terrace.
A modern villa with a swimming pool, outdoor seating, and a stone wall backdrop.
A modern bedroom with a large bed, a glass door leading to a bathroom, and a minimalist design.
A coastal landscape with clear blue waters, rocky cliffs, and a sandy beach.

7. Santorini Heights

Santorini Heights
Santorini
P30,382
P34,645 total
includes taxes & fees
Oct 11 - Oct 12
Santorini Heights
A resort with a pool, white buildings, and a view of the sea at sunset.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.
A sunset view from a rooftop terrace with tables and chairs, overlooking a calm sea and rocky coastline.
A modern living room with a white sofa, a round table, and two windows offering a view of the sea.

8. Grace Hotel, Auberge Collection

Grace Hotel, Auberge Collection
Santorini
  • Seaside luxury meets winery charm at this Santorini hotel offering spa treatments and ocean views.
P37,489
P45,742 total
includes taxes & fees
Oct 26 - Oct 27
Grace Hotel, Auberge Collection
An infinity pool with a view of the sea and distant islands.
A balcony with a table, a chair, and a white umbrella overlooking a coastal view with a boat on the water and buildings on the cliff.
A room with a view of a mountainous coastline, a potted orchid, a book on the table, and two chairs.
A room with a wooden floor, white walls, and a view of the sea through open doors. There is a white chair, a small round table with apples, and a potted plant.

9. Katikies Santorini – Pelagos House - The Leading Hotels of the World

Katikies Santorini – Pelagos House - The Leading Hotels of the World
Santorini
  • Cliffside serenity meets island elegance at this Santorini retreat with 3 sparkling pools and spa indulgences.
P28,718
P33,670 total
includes taxes & fees
Oct 25 - Oct 26
Katikies Santorini – Pelagos House - The Leading Hotels of the World
An infinity pool with clear blue water and white lounge chairs, overlooking a calm sea and distant islands.
A bedroom with a large bed, a view of the sea, and a bathroom with a shower.
An open doorway leading to a balcony with a view of the sea and a distant island.
A modern living room with a large sliding glass door leading to a balcony with a sea view.

10. Canaves Oia Suites - Small Luxury Hotels of the World

Canaves Oia Suites - Small Luxury Hotels of the World
Santorini
  • Seaside luxury with ocean views, a full-service spa, and attentive service at this Santorini retreat just steps from Caldera shores.
P39,628
P46,059 total
includes taxes & fees
Oct 31 - Nov 1
Canaves Oia Suites - Small Luxury Hotels of the World
View all properties

Top Megalochori Hotel Reviews

Caldera Premium Villas - Adults Only

Caldera Premium Villas - Adults Only

10/10 Excellent
"Beautiful views, great rooms. Amazing breakfast and a lovely women serving us!"
Danielle 2-night trip
Posted 21 hours ago
Caldera Premium Villas - Adults Only
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

10/10 Excellent
"We absolutely loved this place!! The staff was so amazing and attentive!! The “Maria’s” knew exactly how we liked our coffee, breakfast and drinks!! So kind and attentive! The front desk people (Katarina, can’t remember the nice man’s name) were so helpful with everything!! I lost my luggage and they helped so much to get it back. The rooms were very clean and plenty of room. Staff came in everyday and made bed etc. The pool area is beautiful and quick walk to the beach! Also quick walk into town. I would go back in a heartbeat!! Loved it all! Liz and Scott"
Elizabeth 5-night trip
Posted 3 days ago
Santo Pure Oia Suites & Villas
White Pearl Villas

White Pearl Villas

10/10 Excellent
"Amazing that it’s AMAZING"
Jonathan 5-night trip
Posted 5 days ago
White Pearl Villas
Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only

10/10 Excellent
"El hotel en general está en buenas condiciones, limpio y el personal siempre amable y atento para ayudar resolviendo dudas, la habitación excelente vista un súper plus saliendo teníamos la piscina. También súper cercano a tiendas de souvenirs y algunas opciones de buenos restaurantes con excelentes vistas !"
Eva 2-night trip
Posted 9 days ago
Ira Hotel & Spa - Adults Only
Volcano View Hotel Santorini

Volcano View Hotel Santorini

10/10 Excellent
"Beautiful property with spectacular Caldera views. A number of restaurants nearby. Great staff."
Mark 2-night trip
Posted 9 days ago
Volcano View Hotel Santorini

Frequently asked questions

Are you looking for a luxury hotel for your Megalochori vacation?
Fly into Santorini National Airport (JTR) Airport and then pamper yourself by staying at one of 5 Megalochori luxury hotels. Megalochori has some interesting things to see and do including Santorini Caldera and Gavalas Vineyard, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in Megalochori?
May Seven Santorini is a luxury guesthouse with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Vedema, a Luxury Collection Resort, Santorini and Enarma Suites & Spa Wellness Retreat are two other upscale options for your vacation.
How many luxury hotels will I find in Megalochori?
Lie in the lap of luxury during your getaway to Megalochori in one of Expedia's 5 luxury hotels.
When can I expect good weather in Megalochori?
Planning for the weather is a good way to make your trip to Megalochori relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 76°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Megalochori is 13 inches.
What's there to see and do in Megalochori?
Enjoy all that Megalochori has to offer and visit Santorini Caldera, Gavalas Vineyard, and Boutari Winery. If you have a bit of extra time while you're in the area, you might want to check out Athinios Port and Venetsanos Winery.