Main Street Hyannis

A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.
Street signs for Waterfront, Fishing/Tour Boats, and Street.
A street with ice cream shops and a skate shop.
A red brick building with a white arched entrance, a large clock, and a window with an air conditioning unit.
A directional sign with 'Waterfront' and 'Fishing/Tour Boats' pointing to the left.


Things to do

Stay near popular Main Street Hyannis attractions


Top Hotel Deals

Bayside Resort Hotel

Bayside Resort Hotel

3 out of 5
225 Route 28 West Yarmouth MA
Bayside Resort Hotel
Hyannis Harbor Hotel

Hyannis Harbor Hotel

3.5 out of 5
213 Ocean St Hyannis MA
Hyannis Harbor Hotel
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
1225 Iyannough Rd Hyannis MA
Margaritaville Resort Cape Cod
Hyannis Travel Inn

Hyannis Travel Inn

2.5 out of 5
18 North St Hyannis MA
Hyannis Travel Inn
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

4 out of 5
135 Route 28 West Yarmouth MA
Uncommoner Hotel by Reverie Boutique Collection
Cape Sands Inn

Cape Sands Inn

2.5 out of 5
149 Main St - RT 28 West Yarmouth MA
Cape Sands Inn
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

2.5 out of 5
540 Old Colony Rd Hyannis MA
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Cape Cod Inn

Cape Cod Inn

2 out of 5
447 Main St Hyannis MA
Cape Cod Inn
Ocean Street Inn on Hyannis Harbor

Ocean Street Inn on Hyannis Harbor

2 out of 5
131 Ocean St Hyannis MA
Ocean Street Inn on Hyannis Harbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.