Main Street Fort Pierce Hotels, Fort Pierce

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Our top choices for Main Street Fort Pierce hotels

A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.

1. Fairfield Inn & Suites by Marriott Fort Pierce

7.7 km from Main Street Fort Pierce

Katherine

P6,490 total

includes taxes & fees

Oct 4 - Oct 5

A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.

2. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

8.3 km from Main Street Fort Pierce

Iosif

P7,355 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a long dining table, multiple chairs, and a coffee bar with various beverages.

3. Hampton Inn & Suites Ft. Pierce

7.9 km from Main Street Fort Pierce

Angela

P6,835 total

includes taxes & fees

Oct 25 - Oct 26

A pool area with lounge chairs and a hot tub, surrounded by palm trees and a view of the ocean.

4. Hutchinson Island Hotel

3.1 km from Main Street Fort Pierce

Kathleen

P7,649 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor seating area with fire feature, stone walls, and a view into the building.

5. Home2 Suites by Hilton Ft. Pierce I-95

7.8 km from Main Street Fort Pierce

JERRY

P7,989 total

includes taxes & fees

Oct 15 - Oct 16

A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7.9 km from Main Street Fort Pierce

riad

P6,164 total

includes taxes & fees

Oct 2 - Oct 3

A hotel lobby with a reception desk, seating area, and a hallway leading to other rooms.

7. Days Inn & Suites by Wyndham Fort Pierce I-95

7.8 km from Main Street Fort Pierce

Carlton

P4,328 total

includes taxes & fees

Oct 11 - Oct 12

A hotel entrance with a welcome sign, a black mat, and two potted plants.

8. At Home Inn

8.2 km from Main Street Fort Pierce

Eric

P4,021 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with a bed, a sofa, and a small table. There are framed pictures on the wall.

9. Comfort Suites Fort Pierce I-95

7.7 km from Main Street Fort Pierce

Marina

P7,585 total

includes taxes & fees

Oct 13 - Oct 14

A hotel lobby with a reception desk, a chandelier, a clock, and a sofa.

10. Sleep Inn Fort Pierce I-95

7.9 km from Main Street Fort Pierce

Charity

P4,824 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with two beds, a television, a ceiling fan, and a view of the beach.

11. The Royal Inn Beach Hotel Hutchinson Island

3.8 km from Main Street Fort Pierce

Taylor

P7,877 total

includes taxes & fees

Oct 2 - Oct 3

A Holiday Inn Express & Suites hotel with a modern design, featuring a prominent entrance, well-maintained landscaping, and a clear view of the sky.

12. Holiday Inn Express & Suites Port St. Lucie West by IHG

17.1 km from Main Street Fort Pierce

AEON

P8,336 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story hotel with a modern design, featuring a prominent sign for 'Springhill Suites Marriott'.

13. SpringHill Suites Port St. Lucie

17.2 km from Main Street Fort Pierce

Kevin

P7,187 total

includes taxes & fees

Oct 6 - Oct 7

A modern living room with a fireplace, a dining area with bar stools, and a large TV mounted on the wall.

14. Hampton Inn & Suites Vero Beach Downtown

22.1 km from Main Street Fort Pierce

Cameron

P9,707 total

includes taxes & fees

Oct 12 - Oct 13

A clear blue swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a gazebo.

15. Best Western Port St. Lucie

14 km from Main Street Fort Pierce

Andrew

P6,304 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

16. Staybridge Suites Vero Beach by IHG

24.1 km from Main Street Fort Pierce

Christine

P8,686 total

includes taxes & fees

Oct 18 - Oct 19

A restaurant interior with a bar area, wooden flooring, and multiple seating arrangements.

17. Days Inn & Suites by Wyndham Fort Pierce Midtown

4.5 km from Main Street Fort Pierce

Cynthia

P4,287 total

includes taxes & fees

Oct 7 - Oct 8

A spacious hotel lobby with seating areas, a kitchenette, and large windows.

18. Hampton Inn & Suites Port St. Lucie, West

17.4 km from Main Street Fort Pierce

Hilton

P6,357 total

includes taxes & fees

Oct 31 - Nov 1

An outdoor patio area with a fire pit, red and black wicker furniture, and string lights.

19. Residence Inn by Marriott Port St. Lucie

17.8 km from Main Street Fort Pierce

Eduardo

P7,075 total

includes taxes & fees

Oct 18 - Oct 19

A modern bar area with wooden tables and blue chairs, featuring black pendant lights and a large abstract mural on the wall.

20. TownePlace Suites by Marriott Port St. Lucie I-95

21.9 km from Main Street Fort Pierce

Demonica

P7,502 total

includes taxes & fees

Oct 18 - Oct 19

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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.

A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, McKee Botanical Garden and Avalon State Park are some notable places to visit nearby.

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Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Harbor Branch Ocean Discovery Center and McKee Botanical Garden.

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A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

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A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

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A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

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Top Main Street Fort Pierce Hotel Reviews

voco Sandpiper All-Inclusive Resort by IHG

10/10 Excellent

"The only thing I felt that this property needed was better variety in music, more diverse music, instead of just steel drums that was driving me insane and I think they need a better variety of food also."

Tru by Hilton Port St. Lucie Tradition

10/10 Excellent

"I absolutely loved everything about the hotel. The reception was great & I was treated like royalty from beginning to the end of my stay & the manager Kaitlyn was the best ! This was the first time I stayed at a Tru, by Hilton property & I found it to be the best in its class and I will be looking to stay with Tru wherever future travels take me, as it surpassed all other hotels on all levels & areas🙌"

Frequently asked questions

What is Main Street Fort Pierce like?

Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce Farmer's Market as part of your Main Street Fort Pierce travel plans.

How many hotels can I expect to find in Main Street Fort Pierce?

Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.

If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.

What is there to do in this Fort Pierce neighborhood?

Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce Farmer's Market and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.

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Main Street Fort Pierce Hotels near Fort Pierce

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Treat yourself

Be picky

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Our top choices for Main Street Fort Pierce hotels

1. Fairfield Inn & Suites by Marriott Fort Pierce

2. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

3. Hampton Inn & Suites Ft. Pierce

4. Hutchinson Island Hotel

5. Home2 Suites by Hilton Ft. Pierce I-95

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7. Days Inn & Suites by Wyndham Fort Pierce I-95

8. At Home Inn

9. Comfort Suites Fort Pierce I-95

10. Sleep Inn Fort Pierce I-95

11. The Royal Inn Beach Hotel Hutchinson Island

12. Holiday Inn Express & Suites Port St. Lucie West by IHG

13. SpringHill Suites Port St. Lucie

14. Hampton Inn & Suites Vero Beach Downtown

15. Best Western Port St. Lucie

16. Staybridge Suites Vero Beach by IHG

17. Days Inn & Suites by Wyndham Fort Pierce Midtown

18. Hampton Inn & Suites Port St. Lucie, West

19. Residence Inn by Marriott Port St. Lucie

20. TownePlace Suites by Marriott Port St. Lucie I-95

Where to stay in Main Street Fort Pierce

Lakewood Park

Spanish Lakes Country Club Village

Spanish Lakes Fairways

Meadowood

Panther Woods

Top Main Street Fort Pierce Hotel Reviews

voco Sandpiper All-Inclusive Resort by IHG

Frequently asked questions

Explore a world of travel with Expedia