Main Street Fort Pierce Hotels near Fort Pierce

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Dec 29 - Dec 30
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Dec 30 - Dec 31
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Jan 2 - Jan 4
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Jan 9 - Jan 11

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Our top choices for Main Street Fort Pierce hotels

Marina
The Old Apartment

The Old Apartment

The Old Apartment
4.0 star property
Main Street Fort Pierce
The Old Apartment
Exterior
At Home Inn

At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very Good, (1011)
"Staff was very friendly and informative."
United States
Mary
The price is P3,782
P4,236 total
includes taxes & fees
Dec 30 - Dec 31
At Home Inn
Reception
Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition
2.5 star property
23.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (762)
" I’ve stayed twice and it’s been an excellent experience. Clean facilities and great staff. "
United States
Daniel
The price is P5,507
P6,168 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru by Hilton Port St. Lucie Tradition
Desk, free WiFi, bed sheets
Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
25.6 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (608)
"Love staying here. The staff are wonderful, the rooms are clean and the breakfast is decent with lots of options. "
United States
Heather
The price is P7,659
P8,540 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Home2 Suites by Hilton Stuart
Outdoor pool, pool umbrellas, sun loungers
The Caribbean Court Boutique Hotel

The Caribbean Court Boutique Hotel

The Caribbean Court Boutique Hotel
3.0 star property
20.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (862)
"Quiet, extremely clean, super helpful staff, nice pool, and very comfortable bed. Convenient to have restaurant on property. Great place for a couples getaway. "
United States
Jeffrey
The price is P7,440
P8,333 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Caribbean Court Boutique Hotel
Exterior
Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
26.1 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1004)
"Staff warm and friendly and helpful with local spots to visit! "
United States
CHRISTY
The price is P7,659
P8,540 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Stuart-North
Terrace/patio
Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (168)
"Convenient location and good breakfast "
United States
Bruce
The price is P7,167
P8,027 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Home2 Suites by Hilton Ft. Pierce I-95
Property amenity
Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
2.5 star property
7.7 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1006)
"everything was clean and the breakfast was great"
United States
Jim
The price is P5,698
P6,382 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fairfield Inn & Suites by Marriott Fort Pierce
Sundeck
Prestige Hotel Vero Beach

Prestige Hotel Vero Beach

Prestige Hotel Vero Beach
2.0 star property
20.5 km from Main Street Fort Pierce
8.4 out of 10, Very Good, (1000)
"Great place"
United States
Rosa
The price is P7,578
P8,488 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Prestige Hotel Vero Beach
Breakfast, lunch, dinner served; American cuisine, beach views
Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach
3.5 star property
23.2 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1098)
"LOVE the oceanfront room. The roar of the ocean is wonderful!"
United States
Sylvia F.
The price is P8,460
P9,475 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Ocean Breeze Inn Vero Beach
Outdoor pool, pool umbrellas, sun loungers
Costa d'Este Beach Resort and Spa

Costa d'Este Beach Resort and Spa

Costa d'Este Beach Resort and Spa
4.0 star property
23 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1002)
"Great vibe and location"
United States
Stephanie
The price is P14,522
P19,028 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Costa d'Este Beach Resort and Spa
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (810)
"The front desk was super friendly and very accommodating. Super fast check in and room was perfect. Thank you "
United States
shelley
The price is P7,461
P8,356 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
BBQ/picnic area
Seahorse Beach Bungalows

Seahorse Beach Bungalows

Seahorse Beach Bungalows
2.0 star property
4.8 km from Main Street Fort Pierce
8.0 out of 10, Very Good, (78)
"Location is prime. Walking distance to the beach. The room has everything you need for a good stay. My husband and I are returning for sure!"
United States
Cibele
The price is P3,525
P5,416 total
includes taxes & fees
Dec 30 - Dec 31
Seahorse Beach Bungalows
On the beach, sun loungers, beach umbrellas, beach towels
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
25.2 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1002)
"I would definitely visit again."
United States
Cassandra
The price is P13,990
P18,231 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hutchinson Shores Resort & Spa
Outdoor spa tub
Hutchinson Island Hotel

Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.4 out of 10, Very Good, (1352)
"The room was Excellent staff was very friendly I love the fishing dock the local restaurants service and food was great I'll be visiting there again soon "
United States
Darryl
Hutchinson Island Hotel
Outdoor pool, sun loungers
Hampton Inn Vero Beach

Hampton Inn Vero Beach

Hampton Inn Vero Beach
2.5 star property
28.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1003)
"Great place to stay! Sabrina at check-in was amazing! I would definitely recommend staying here. "
United States
Troy
The price is P6,311
P7,068 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Vero Beach
Bar (on property)
The Lucie

The Lucie

The Lucie
3.0 star property
23.6 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1003)
"Great stay, excellent staff. "
United States
Steve
The price is P10,116
P13,633 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Lucie
Outdoor pool, sun loungers
Best Western Downtown Stuart

Best Western Downtown Stuart

Best Western Downtown Stuart
3.0 star property
29.8 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1005)
"Staff were courteous, room was clean, breakfast was good."
United States
CRAIG
The price is P7,607
P8,519 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Downtown Stuart
BBQ/picnic area
Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie
3.0 star property
17.8 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1005)
"Great stay! Very friendly staff "
United States
Giovanni
The price is P7,461
P8,356 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Residence Inn by Marriott Port St. Lucie
Free daily on-the-go breakfast
Hotel Flamingo Inn & Suites Vero Beach I-95

Hotel Flamingo Inn & Suites Vero Beach I-95

Hotel Flamingo Inn & Suites Vero Beach I-95
2.5 star property
28.6 km from Main Street Fort Pierce
7.6 out of 10, Good, (1004)
"Clean room convenient decent breakfast "
United States
Andrew
The price is P3,965
P4,441 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Flamingo Inn & Suites Vero Beach I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.

Lakewood Park

While Lakewood Park isn't home to many top sights, Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and McKee Botanical Garden.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Lakewood Park Regional Park / Pool.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Indrio Road Park / Schoolhouse.

Top Main Street Fort Pierce Hotel Reviews

The Lucie

The Lucie

10/10 Excellent
"The room was great, the view of sunrise was fantastic, and everyone had a smile!"
Jim 2-night trip
Posted 7 hours ago
The Lucie

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Downtown Fort Pierce and Sunrise Theater as part of your Main Street Fort Pierce travel plans.
How many hotels can I expect to find in Main Street Fort Pierce?
Book one of Expedia's 5 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.
What is there to do in this Fort Pierce neighborhood?
For cultural attractions in Main Street Fort Pierce, head to Sunrise Theater, Art Mundo, and Official Highwaymen Art Gallery. Downtown Fort Pierce and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Fort Pierce Farmer's Market, Manatee Education and Observation Center, and House of Seven Gables. A.E. Backus Museum and Marina at Fort Pierce are also worth a visit when you're out sightseeing in Fort Pierce.

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